Q9AYT7 · MTNA_HORVU
- ProteinMethylthioribose-1-phosphate isomerase
- GeneIDI2
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids367 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
function
Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).
Catalytic activity
- S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate
Pathway
Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.
Features
Showing features for site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 170 | Transition state stabilizer | ||||
Sequence: C | ||||||
Active site | 250 | Proton donor | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Cellular Component | nucleus | |
Molecular Function | S-methyl-5-thioribose-1-phosphate isomerase activity | |
Biological Process | L-methionine salvage from methylthioadenosine | |
Biological Process | L-methionine salvage from S-adenosylmethionine |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameMethylthioribose-1-phosphate isomerase
- EC number
- Short namesM1Pi ; MTR-1-P isomerase
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Pooideae > Triticodae > Triticeae > Hordeinae > Hordeum
Accessions
- Primary accessionQ9AYT7
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000401990 | 1-367 | Methylthioribose-1-phosphate isomerase | |||
Sequence: MGESSALQSILYGRGALRLLDQRKLPLEEVYVDVKDSADGWNAIRDMVVRGAPAIAIAAALSLAVEVNDHNFIGTPAEAASFVSKKLEYLVSSRPTAVNLSDAATKLQNLVSTTAETAKDAKSIFQVFIEAAETMLVDDVADNKAIGLHGAEFLQRQLGSSKNISVLTHCNTGSLATAGYGTALGVIRALHSGGVLEKAFCTETRPFNQGSRLTAFELVHDKIPATLIADSAAAALMNNGQVQAVIVGADRIAANGDTANKIGTYNLSIAAKHHGVQFYVAAPVTSIDLSLPSGKQIVIEERSPKELLNSEGGLGKQVAASGISVWNPAFDVTPADLITAIITEKGVITKSDPDGTFDIKSFIECAK |
Expression
Structure
Family & Domains
Sequence similarities
Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
Family and domain databases
Sequence
- Sequence statusComplete
- Length367
- Mass (Da)38,575
- Last updated2001-06-01 v1
- Checksum7A28005A3273B8D2