Q9ABR0 · PSSY_CAUVC
- ProteinUDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase
- GenepssY
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids267 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Is likely the initiating enzyme for holdfast polysaccharide synthesis. Catalyzes the transfer of the glucose-1-phosphate moiety from UDP-Glc onto the carrier lipid undecaprenyl phosphate (C55-P), forming a phosphoanhydride bond yielding to glucosyl-pyrophosphoryl-undecaprenol (Glc-PP-C55). Also possesses a weak galactose-1-P transferase activity.
Miscellaneous
Complements colanic acid (CA) synthesis in the E.coli mutant lacking wcaJ. Can also partially complement the O-antigen defect in the S.typhimurium wbaP deletion strain (PubMed:22408159).
Catalytic activity
- di-trans,octa-cis-undecaprenyl phosphate + UDP-alpha-D-glucose = alpha-D-glucosyl di-trans,octa-cis-undecaprenyl diphosphate + UMP
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | glycosyltransferase activity | |
Molecular Function | undecaprenyl-phosphate glucose phosphotransferase activity | |
Biological Process | colanic acid biosynthetic process | |
Biological Process | polysaccharide biosynthetic process |
Keywords
- Molecular function
- Biological process
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameUDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase
- EC number
- Short namesUDP-Glc:Und-P Glc-1-P transferase
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Caulobacterales > Caulobacteraceae > Caulobacter
Accessions
- Primary accessionQ9ABR0
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 83-103 | Helical | ||||
Sequence: VAAALLTALFAPLLLLAALAI |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000422393 | 1-267 | UDP-glucose:undecaprenyl-phosphate glucose-1-phosphate transferase | |||
Sequence: MKEQGLPAVNIIACASPLLCTTTSSDCVSVWACELEQPLSDALGKLKDHPVDLGPSTQLLTLRPGGPLPRVAVDLRKRVLDVVAAALLTALFAPLLLLAALAIKLESPGPALFRQTRGGLGGAPFQILKLRTMHCREDGPDVAQAQRGDDRVTRVGRILRAASIDELPQLLNVLRGDMSLVGPRPHATAHDDYYSARIPEYAARYQARPGLTGLAQVRGLRGGTETVELMRQRIAADIDYIQTWSLWRDLKIVLRTVPSLLTTDNAY |
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length267
- Mass (Da)29,010
- Last updated2001-06-01 v1
- ChecksumBFFD221591C24988
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE005673 EMBL· GenBank· DDBJ | AAK22153.1 EMBL· GenBank· DDBJ | Genomic DNA |