Q9A6V2 · FLUC_CAUVC

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site76Na+ (UniProtKB | ChEBI); structural
Binding site79Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC

Gene names

    • Name
      fluC
    • Synonyms
      crcB
    • Ordered locus names
      CC_1981

Organism names

Accessions

  • Primary accession
    Q9A6V2

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane4-24Helical
Transmembrane36-56Helical
Transmembrane72-92Helical
Transmembrane101-121Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001100831-127Fluoride-specific ion channel FluC

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    127
  • Mass (Da)
    13,230
  • Last updated
    2001-06-01 v1
  • Checksum
    F0BFD318B382590A
MNKLLLVAAGGAVGSVARYLVGVGAMRVMGPGWPYGTFTVNVVGGFLMGCLASWLAHRGNTSSETWRVMLGVGVLGGFTTFSSFSLETALMIQKRAYGQAFTYSAASVLLAIAALFAGLLVARKVFA

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE005673
EMBL· GenBank· DDBJ
AAK23956.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
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