Q99LH9 · 3BP5L_MOUSE
- ProteinSH3 domain-binding protein 5-like
- GeneSh3bp5l
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids392 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score2/5
Function
function
Functions as a guanine nucleotide exchange factor (GEF) for RAB11A.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Molecular Function | guanyl-nucleotide exchange factor activity | |
Biological Process | intracellular signal transduction |
Keywords
- Molecular function
Names & Taxonomy
Protein names
- Recommended nameSH3 domain-binding protein 5-like
- Short namesSH3BP-5-like
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ99LH9
- Secondary accessions
Proteomes
Organism-specific databases
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000317509 | 1-392 | SH3 domain-binding protein 5-like | |||
Sequence: MADLKKAAGGRETPQGELRSEVVEDEGPRSPVAEEPGGSGSNSSETKLSPREEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMADKNRLDPTWQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGLPPHPLGPRRSSPVGAEAGPEGIEDGDSGIEGAEGGGLEEGSSLGPGPGPDTDTLSLLSLRTVASDLQKCDSVEHLRGLSDHASLDGQELGAQSRGRRGSDIGVRGGRHQRSVSL | ||||||
Modified residue | 13 | Phosphothreonine | ||||
Sequence: T | ||||||
Modified residue | 30 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 49 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 342 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 349 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 357 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 361 | Phosphoserine | ||||
Sequence: S | ||||||
Modified residue | 377 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for compositional bias, region, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-31 | Basic and acidic residues | ||||
Sequence: MADLKKAAGGRETPQGELRSEVVEDEGPRSP | ||||||
Region | 1-57 | Disordered | ||||
Sequence: MADLKKAAGGRETPQGELRSEVVEDEGPRSPVAEEPGGSGSNSSETKLSPREEEELD | ||||||
Coiled coil | 59-140 | |||||
Sequence: RIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIEKARPYYEARRLAKEAQQETQKAALRYERA | ||||||
Coiled coil | 169-272 | |||||
Sequence: WQEMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKAQFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIH | ||||||
Region | 275-332 | Disordered | ||||
Sequence: RRGLPPHPLGPRRSSPVGAEAGPEGIEDGDSGIEGAEGGGLEEGSSLGPGPGPDTDTL | ||||||
Region | 364-392 | Disordered | ||||
Sequence: GQELGAQSRGRRGSDIGVRGGRHQRSVSL |
Sequence similarities
Belongs to the SH3BP5 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length392
- Mass (Da)43,374
- Last updated2001-06-01 v1
- ChecksumE80AEED11306392C
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1-31 | Basic and acidic residues | ||||
Sequence: MADLKKAAGGRETPQGELRSEVVEDEGPRSP | ||||||
Sequence conflict | 148 | in Ref. 1; BAC39606 | ||||
Sequence: R → P | ||||||
Sequence conflict | 181 | in Ref. 1; BAC39606 | ||||
Sequence: N → K | ||||||
Sequence conflict | 304 | in Ref. 1; BAE26141 | ||||
Sequence: D → N |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AK086088 EMBL· GenBank· DDBJ | BAC39606.1 EMBL· GenBank· DDBJ | mRNA | ||
AK144928 EMBL· GenBank· DDBJ | BAE26141.1 EMBL· GenBank· DDBJ | mRNA | ||
AK156171 EMBL· GenBank· DDBJ | BAE33611.1 EMBL· GenBank· DDBJ | mRNA | ||
AK172333 EMBL· GenBank· DDBJ | BAE42951.1 EMBL· GenBank· DDBJ | mRNA | ||
AL845463 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
BC003251 EMBL· GenBank· DDBJ | AAH03251.1 EMBL· GenBank· DDBJ | mRNA | ||
BC094418 EMBL· GenBank· DDBJ | AAH94418.1 EMBL· GenBank· DDBJ | mRNA | ||
BC013661 EMBL· GenBank· DDBJ | AAH13661.1 EMBL· GenBank· DDBJ | mRNA |