We have reconstituted the complete extracellular region of the RET signaling complex together with Neurturin (NRTN) and GFRalpha2 and determined its structure at 5.7-A resolution by cryo-EM. The proteins form an assembly through RET-GFRalpha2 and RET-NRTN interfaces.
Categories
Family & Domains, Interaction, Structure, Structure
In the cochlea NTN immunostaining was found in the supporting cells of organ of Corti including Deiters' cells Hensen cells as well as Claudius' cells. In the spiral ganglia NTN was seen in both the cell bodies and the nerve fibers of neurons.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.