Q99299 · AIM44_YEAST
- ProteinAltered inheritance of mitochondria protein 44
- GeneAIM44
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids758 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
Miscellaneous
Present with 238 molecules/cell in log phase SD medium.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | cell division site | |
Cellular Component | cellular bud neck | |
Cellular Component | cellular bud neck septin collar | |
Cellular Component | cellular bud neck split septin rings | |
Cellular Component | cellular bud tip | |
Cellular Component | nuclear inner membrane | |
Cellular Component | plasma membrane | |
Biological Process | maintenance of protein location | |
Biological Process | positive regulation of mitotic actomyosin contractile ring contraction | |
Biological Process | protein localization to cell division site after cytokinesis | |
Biological Process | regulation of protein localization to cell division site | |
Biological Process | secondary cell septum biogenesis |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAltered inheritance of mitochondria protein 44
Gene names
Organism names
- Strains
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Saccharomycotina > Saccharomycetes > Saccharomycetales > Saccharomycetaceae > Saccharomyces
Accessions
- Primary accessionQ99299
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Phenotypes & Variants
Disruption phenotype
Increases frequency of mitochondrial genome loss.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 51 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000203491 | 1-758 | Altered inheritance of mitochondria protein 44 | |||
Sequence: MIIRAPIRTKTKSFRGDQMDFKFPSNESLPRGTLEEYHLNNHHLLNDVFAAENGVSRDEDGNSQTLSDYTSTSNTNTNSGYSSNGYYSFANISDNTTSSPRIVINQNETARLTSSDSNKSDFFASHDFPGNDSLHYSSSNVVKNQLHSMEAIPEGNITGSISTAFQTIPTADNVSYDIAPSSASSLLPRKSTSKSAILPSTQEAKPMTKLNMEKDIKTIELNNSVVPKPKKKLNRVPTIRRVESSRFSNSRYSSSVSSKSSSSRCSLKRSKAIRCKGGLLYYFTSLGIKIKKKLRKLRLVLRRRLFSYNVQKVPSATNSKTTKSKANINNKSKKRGTNLVNKNSNSTPRQKKSQRYVSNLQRSISSKSLVPVLAPQKKTKPLTVDTKFKANHPQSEDSKVGSNTPRSPLVSYTPSLRRTNSSIRRAASILTASATMTPANNKNSFISVPDNVSHAVTRNSSMYSRSRLVRSKPSTALNAIARQPSIVVENKVIPLSMNRYSIKEEDEYVIDTSSMRELSPVNSVCSSDYDRESSESYSNYADAMETTEVDNKDRVECNNEIQNVDANNEETSNEESYNLMKHYLSTVIAQRIMLRVQIARIQNYKSNVVYMNKSAETNSTIYEDLVDSLLTEYEADGSSSQIFDGVTVRADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEEKRKEGEGRNLAKEVDELAELSPMRKQSDLSITLRSPFAMLNPAYSNSIISLPTGVVKRSLTLPVGMKI | ||||||
Modified residue | 25 | Phosphoserine | ||||
Sequence: S |
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Induction
Expression is controlled by SWI5.
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q99299 | CDC42 P19073 | 4 | EBI-29423, EBI-4274 | |
BINARY | Q99299 | NAP1 P25293 | 5 | EBI-29423, EBI-11850 | |
BINARY | Q99299 | NBA1 Q08229 | 6 | EBI-29423, EBI-36841 | |
BINARY | Q99299 | NIS1 P53939 | 5 | EBI-29423, EBI-28760 | |
BINARY | Q99299 | RHO1 P06780 | 3 | EBI-29423, EBI-15121 |
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for region, compositional bias, coiled coil.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 55-77 | Disordered | ||||
Sequence: VSRDEDGNSQTLSDYTSTSNTNT | ||||||
Compositional bias | 57-77 | Polar residues | ||||
Sequence: RDEDGNSQTLSDYTSTSNTNT | ||||||
Compositional bias | 314-372 | Polar residues | ||||
Sequence: PSATNSKTTKSKANINNKSKKRGTNLVNKNSNSTPRQKKSQRYVSNLQRSISSKSLVPV | ||||||
Region | 314-414 | Disordered | ||||
Sequence: PSATNSKTTKSKANINNKSKKRGTNLVNKNSNSTPRQKKSQRYVSNLQRSISSKSLVPVLAPQKKTKPLTVDTKFKANHPQSEDSKVGSNTPRSPLVSYTP | ||||||
Compositional bias | 395-414 | Polar residues | ||||
Sequence: SEDSKVGSNTPRSPLVSYTP | ||||||
Region | 636-702 | Disordered | ||||
Sequence: DGSSSQIFDGVTVRADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEEKRKEGEGRNLAK | ||||||
Coiled coil | 648-711 | |||||
Sequence: VRADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEEKRKEGEGRNLAKEVDELAELS | ||||||
Compositional bias | 649-690 | Acidic residues | ||||
Sequence: RADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEE |
Sequence similarities
Belongs to the AIM44 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length758
- Mass (Da)84,846
- Last updated1996-11-01 v1
- Checksum3B4FA92B91C87F2B
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 57-77 | Polar residues | ||||
Sequence: RDEDGNSQTLSDYTSTSNTNT | ||||||
Compositional bias | 314-372 | Polar residues | ||||
Sequence: PSATNSKTTKSKANINNKSKKRGTNLVNKNSNSTPRQKKSQRYVSNLQRSISSKSLVPV | ||||||
Compositional bias | 395-414 | Polar residues | ||||
Sequence: SEDSKVGSNTPRSPLVSYTP | ||||||
Compositional bias | 649-690 | Acidic residues | ||||
Sequence: RADEEEEEDEDDEDDEEEEEENDDEEDEEDEEDDEDDEEEEE |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X96770 EMBL· GenBank· DDBJ | CAA65563.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
Z73514 EMBL· GenBank· DDBJ | CAA97863.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
BK006949 EMBL· GenBank· DDBJ | DAA11276.1 EMBL· GenBank· DDBJ | Genomic DNA |