Q99060 · Q99060_TRAVE
- ProteinPeroxidase
- GenePGVII
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids364 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Cofactor
Protein has several cofactor binding sites:
Note: Binds 2 calcium ions per subunit.
Note: Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.
Features
Showing features for site, active site, binding site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Site | 69 | Transition state stabilizer | ||||
Sequence: R | ||||||
Active site | 73 | Proton acceptor | ||||
Sequence: H | ||||||
Binding site | 74 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 92 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 94 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 96 | Ca2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: S | ||||||
Binding site | 202 | Fe (UniProtKB | ChEBI) of heme b (UniProtKB | ChEBI); axial binding residue | ||||
Sequence: H | ||||||
Binding site | 203 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 220 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 222 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: T | ||||||
Binding site | 227 | Ca2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | heme binding | |
Molecular Function | metal ion binding | |
Molecular Function | peroxidase activity | |
Biological Process | cellular response to oxidative stress | |
Biological Process | hydrogen peroxide catabolic process | |
Biological Process | lignin catabolic process | |
Biological Process | response to reactive oxygen species |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended namePeroxidase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Basidiomycota > Agaricomycotina > Agaricomycetes > Polyporales > Polyporaceae > Trametes
Accessions
- Primary accessionQ99060
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-21 | |||||
Sequence: MAFKLLASFVSLLAALQVANG | ||||||
Chain | PRO_5010896868 | 22-364 | Peroxidase | |||
Sequence: AATKKVTCASGQVTSNAACCALFPVIDDIQANMFDGGECNEDVHESLRLTFHDAIGISRKANKAGVFGGGGADGSIAIFADIETNFHANNGVDEIIDTQAPIIARHNLTTADFIQFAGAIGVSNCPGAPRLDVFLGRKDATQPAPDLTVPEPFDDVTKILARFDDAGKFSSDEVVALLVSHTIAAADHVDPTIPGTPFDSTPELFDTQFFIETQLQGTLFPGNGSNQGEVMSPLRGEIRLQSDFLLARDSRTACEWQSFVNNQYKLQSAFKAAFRKMTILGSKEHNLIDCSDVVPTPPAPASKAHLPAGLTRQDVQQACNKKAFPTLPTDPGPVTSVAPVPPS | ||||||
Disulfide bond | 29↔41 | |||||
Sequence: CASGQVTSNAACC | ||||||
Disulfide bond | 40↔311 | |||||
Sequence: CCALFPVIDDIQANMFDGGECNEDVHESLRLTFHDAIGISRKANKAGVFGGGGADGSIAIFADIETNFHANNGVDEIIDTQAPIIARHNLTTADFIQFAGAIGVSNCPGAPRLDVFLGRKDATQPAPDLTVPEPFDDVTKILARFDDAGKFSSDEVVALLVSHTIAAADHVDPTIPGTPFDSTPELFDTQFFIETQLQGTLFPGNGSNQGEVMSPLRGEIRLQSDFLLARDSRTACEWQSFVNNQYKLQSAFKAAFRKMTILGSKEHNLIDC | ||||||
Disulfide bond | 60↔146 | |||||
Sequence: CNEDVHESLRLTFHDAIGISRKANKAGVFGGGGADGSIAIFADIETNFHANNGVDEIIDTQAPIIARHNLTTADFIQFAGAIGVSNC | ||||||
Disulfide bond | 275↔340 | |||||
Sequence: CEWQSFVNNQYKLQSAFKAAFRKMTILGSKEHNLIDCSDVVPTPPAPASKAHLPAGLTRQDVQQAC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 68-344 | Plant heme peroxidase family profile | ||||
Sequence: LRLTFHDAIGISRKANKAGVFGGGGADGSIAIFADIETNFHANNGVDEIIDTQAPIIARHNLTTADFIQFAGAIGVSNCPGAPRLDVFLGRKDATQPAPDLTVPEPFDDVTKILARFDDAGKFSSDEVVALLVSHTIAAADHVDPTIPGTPFDSTPELFDTQFFIETQLQGTLFPGNGSNQGEVMSPLRGEIRLQSDFLLARDSRTACEWQSFVNNQYKLQSAFKAAFRKMTILGSKEHNLIDCSDVVPTPPAPASKAHLPAGLTRQDVQQACNKKA | ||||||
Region | 343-364 | Disordered | ||||
Sequence: KAFPTLPTDPGPVTSVAPVPPS |
Sequence similarities
Belongs to the peroxidase family. Ligninase subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length364
- Mass (Da)38,597
- Last updated1996-11-01 v1
- Checksum8022FE78D678545A