Q98300 · A28_MCV1

Function

function

Envelope protein required for virus entry into host cell and for cell-cell fusion (syncytium formation).

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Cellular Componentviral envelope
Cellular Componentvirion membrane
Biological Processmembrane fusion involved in viral entry into host cell
Biological Processsymbiont entry into host cell

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Envelope protein A28 homolog
  • Alternative names
    • Protein MC134

Gene names

    • Ordered locus names
      MC134L

Organism names

Accessions

  • Primary accession
    Q98300

Proteomes

Subcellular Location

Virion membrane
; Single-pass type II membrane protein
Note: Component of the intracellular mature virion (IMV) membrane.

Features

Showing features for transmembrane, topological domain.

TypeIDPosition(s)Description
Transmembrane1-21Helical; Signal-anchor for type II membrane protein
Topological domain22-140Virion surface

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00000992931-141Envelope protein A28 homolog

Post-translational modification

Contains two intramolecular disulfide bonds. They are created by the viral disulfide bond formation pathway, a poxvirus-specific pathway that operates on the cytoplasmic side of the MV membranes (By similarity).

Keywords

Expression

Keywords

Structure

3D structure databases

Family & Domains

Sequence similarities

Belongs to the poxviridae A28 protein family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    141
  • Mass (Da)
    15,354
  • Last updated
    1997-02-01 v1
  • Checksum
    0BD4DD3A5A20FCEB
MDPLSVFFLVVAAAAVCTLLLQAYAVYENFDSILEFNDAHASLEYSKSLGGSYIDKHVFDPNDGVADVTQKWRCALYGKVYVSASAFGFYAQPDGSKRTFSTRDDCVDFTFGTADTSRVVNPCTDPNGAQAEDCAFLKSVL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U60315
EMBL· GenBank· DDBJ
AAC55262.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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