Q980Q7 · NDK_SACS2

Function

function

Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site11ATP (UniProtKB | ChEBI)
Binding site59ATP (UniProtKB | ChEBI)
Binding site87ATP (UniProtKB | ChEBI)
Binding site93ATP (UniProtKB | ChEBI)
Binding site104ATP (UniProtKB | ChEBI)
Binding site114ATP (UniProtKB | ChEBI)
Active site117Pros-phosphohistidine intermediate

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionnucleoside diphosphate kinase activity
Biological ProcessCTP biosynthetic process
Biological ProcessGTP biosynthetic process
Biological Processphosphorylation
Biological ProcessUTP biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Nucleoside diphosphate kinase
  • EC number
  • Short names
    NDK
    ; NDP kinase
  • Alternative names
    • Nucleoside-2-P kinase

Gene names

    • Name
      ndk
    • Ordered locus names
      SSO0230

Organism names

Accessions

  • Primary accession
    Q980Q7

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001371021-138Nucleoside diphosphate kinase

Keywords

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the NDK family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    138
  • Mass (Da)
    15,554
  • Last updated
    2001-09-26 v1
  • Checksum
    390714D857913B24
MVAQRTFVMIKPDGVKRGLIGEIISRFEKRGLKIVSLKMVKMSRDTAEKLYEEHKGKSFFEELVNYVTSGPVVCMVIEGDDVVQVIRRMIGNTDPKEAPPGTIRGDYALSKSENVIHASDSIEKAQREMSLFFDKSDL

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE006641
EMBL· GenBank· DDBJ
AAK40571.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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