Q980L7 · ATGT_SACS2
- ProteintRNA-guanine(15) transglycosylase
- GenetgtA
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids503 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.
Catalytic activity
- guanosine15 in tRNA + 7-cyano-7-deazaguanine = 7-cyano-7-carbaguanosine15 in tRNA + guanine
Cofactor
Note: Binds 1 zinc ion per subunit.
Pathway
tRNA modification; archaeosine-tRNA biosynthesis.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 86 | Nucleophile | |||
Binding site | 121 | substrate | |||
Binding site | 278 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 280 | Zn2+ (UniProtKB | ChEBI) | |||
Binding site | 283 | Zn2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | pentosyltransferase activity | |
Molecular Function | zinc ion binding | |
Biological Process | queuosine biosynthetic process | |
Biological Process | tRNA wobble guanine modification |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nametRNA-guanine(15) transglycosylase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Saccharolobus
Accessions
- Primary accessionQ980L7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000247885 | 1-503 | tRNA-guanine15 transglycosylase | ||
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length503
- Mass (Da)58,318
- Last updated2001-10-01 v1
- ChecksumB933A240FB554BCE
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006641 EMBL· GenBank· DDBJ | AAK40613.1 EMBL· GenBank· DDBJ | Genomic DNA |