Q980L7 · ATGT_SACS2

Function

function

Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs.

Catalytic activity

Cofactor

Zn2+ (UniProtKB | Rhea| CHEBI:29105 )

Note: Binds 1 zinc ion per subunit.

Pathway

tRNA modification; archaeosine-tRNA biosynthesis.

Features

Showing features for active site, binding site.

Type
IDPosition(s)Description
Active site86Nucleophile
Binding site121substrate
Binding site278Zn2+ (UniProtKB | ChEBI)
Binding site280Zn2+ (UniProtKB | ChEBI)
Binding site283Zn2+ (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentcytoplasm
Molecular Functionpentosyltransferase activity
Molecular Functionzinc ion binding
Biological Processqueuosine biosynthetic process
Biological ProcesstRNA wobble guanine modification

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    tRNA-guanine(15) transglycosylase
  • EC number
  • Alternative names
    • 7-cyano-7-deazaguanine tRNA-ribosyltransferase
    • Archaeal tRNA-guanine transglycosylase

Gene names

    • Name
      tgtA
    • Ordered locus names
      SSO0274

Organism names

Accessions

  • Primary accession
    Q980L7

Proteomes

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002478851-503tRNA-guanine15 transglycosylase

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the archaeosine tRNA-ribosyltransferase family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    503
  • Mass (Da)
    58,318
  • Last updated
    2001-10-01 v1
  • Checksum
    B933A240FB554BCE
MTVFEVKYEDLAGRIGTLRTRSGTLETPAFFPVINVLKKDEISIDEIRNIGFKNFITNSYILYKNNYIKDDIHKELRSEEMIIMTDSGAYQILEYGEIGITNLQIVNYQLKIKPDIGVILDLPTGNINDYDNAKKTVYETLKRAEEASEIIVKNQDNNIIWVYPIQGGRYLDLVKTSAEGLSKFEHIYNMAALGSPTVLLEKYMYDTVIDMIYTAKSNIKRGIPFHLFGGGLPHIIPFAVALGVDSFDSASYIIYARDNRYITRTRVYKLEDLEYFPCSCPICSKYTPKDLLEMNEKERTKALAIHNLYTILEEFKATKQAIKEGRLFEYLQEKAYSHPAVYSAFKRLMKYKDYLEKFDPRIRGDPKGLFLFDGNSLHRPEIIRHSRFLERYIQKKDKISIYCYDKAISDTAYDFKEKIREKIADRNESDVFIAVPFFGLIPLEISDSYPLSQFEIPNEIDEDVIDDMKTKIISFLRRNNYQKVELINCEKLGLHIDSISTSS

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AE006641
EMBL· GenBank· DDBJ
AAK40613.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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