Q980A7 · CBIX_SACS2
- ProteinSirohydrochlorin cobaltochelatase
- GenecbiX
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids128 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the insertion of Co2+ into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis.
Catalytic activity
- Co-sirohydrochlorin + 2 H+ = sirohydrochlorin + Co2+
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; cob(II)yrinate a,c-diamide from sirohydrochlorin (anaerobic route): step 1/10.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 9 | Proton acceptor | |||
Binding site | 9 | Co2+ (UniProtKB | ChEBI) | |||
Binding site | 43 | substrate | |||
Binding site | 68-73 | substrate | |||
Binding site | 73 | Co2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | cobalt ion binding | |
Molecular Function | sirohydrochlorin cobaltochelatase activity | |
Biological Process | anaerobic cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameSirohydrochlorin cobaltochelatase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Saccharolobus
Accessions
- Primary accessionQ980A7
Proteomes
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000150362 | 1-128 | Sirohydrochlorin cobaltochelatase | ||
Proteomic databases
Interaction
Structure
Family & Domains
Sequence similarities
Belongs to the CbiX family. CbiXS subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length128
- Mass (Da)14,606
- Last updated2001-10-01 v1
- ChecksumAEB6788BFA35775C
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006641 EMBL· GenBank· DDBJ | AAK40738.1 EMBL· GenBank· DDBJ | Genomic DNA |