Q97TZ6 · COBS_SACS2
- ProteinAdenosylcobinamide-GDP ribazoletransferase
- GenecobS
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids253 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.
Catalytic activity
- alpha-ribazole + adenosylcob(III)inamide-GDP = adenosylcob(III)alamin + GMP + H+
Cofactor
Pathway
Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | adenosylcobinamide-GDP ribazoletransferase activity | |
Molecular Function | cobalamin 5'-phosphate synthase activity | |
Biological Process | cobalamin biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAdenosylcobinamide-GDP ribazoletransferase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageArchaea > Thermoproteota > Thermoprotei > Sulfolobales > Sulfolobaceae > Saccharolobus
Accessions
- Primary accessionQ97TZ6
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 33-53 | Helical | ||||
Sequence: ISPIIVGISLGLIESVAYLIL | ||||||
Transmembrane | 106-126 | Helical | ||||
Sequence: VGSGGIGLLLVYLSIQIVALL | ||||||
Transmembrane | 132-152 | Helical | ||||
Sequence: LYTIFYLISSNVLSMSLSLYI | ||||||
Transmembrane | 178-198 | Helical | ||||
Sequence: ILLLELIPFISLYNVIVFIIF |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000146921 | 1-253 | Adenosylcobinamide-GDP ribazoletransferase | |||
Sequence: MHLKEILAQFSFFTAIPVKSSASLEEIAESSYISPIIVGISLGLIESVAYLILYRILGELTGIVLLGIIELLRGFNHLDGLLDLGDALMIRGNREKKIKALKDVEVGSGGIGLLLVYLSIQIVALLKLDFSLYTIFYLISSNVLSMSLSLYILSTISPIPESNLGRIFHDKLKGKSTILLLELIPFISLYNVIVFIIFYMIMYKICGSLGGSSGDIAGASITLSFPLFLITDEITNLNYSLLSILCYLFSHLH |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length253
- Mass (Da)27,831
- Last updated2001-10-01 v1
- ChecksumD69B03290DE5C68A
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006641 EMBL· GenBank· DDBJ | AAK43328.1 EMBL· GenBank· DDBJ | Genomic DNA |