Q96X46 · ENO_PENCI
- ProteinEnolase
- GeneenoA
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids438 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
Catalytic activity
- (2R)-2-phosphoglycerate = phosphoenolpyruvate + H2O
Cofactor
Note: Mg2+ is required for catalysis and for stabilizing the dimer.
Pathway
Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 159 | substrate | |||
Binding site | 168 | substrate | |||
Active site | 211 | Proton donor | |||
Binding site | 246 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 297 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 297 | substrate | |||
Binding site | 322 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 322 | substrate | |||
Active site | 347 | Proton acceptor | |||
Binding site | 374-377 | substrate | |||
Binding site | 398 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | phosphopyruvate hydratase complex | |
Molecular Function | magnesium ion binding | |
Molecular Function | phosphopyruvate hydratase activity | |
Biological Process | glycolytic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameEnolase
- EC number
- Alternative names
- Allergen namePen c 22
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Fungi > Dikarya > Ascomycota > Pezizomycotina > Eurotiomycetes > Eurotiomycetidae > Eurotiales > Aspergillaceae > Penicillium
Accessions
- Primary accessionQ96X46
Subcellular Location
Phenotypes & Variants
Allergenic properties
Causes an allergic reaction in human. Binds to IgE.
Keywords
- Disease
Protein family/group databases
PTM/Processing
Features
Showing features for initiator methionine, chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Initiator methionine | 1 | Removed | |||
Chain | PRO_0000134056 | 2-438 | Enolase | ||
Interaction
Subunit
Homodimer.
Structure
Sequence
- Sequence statusComplete
- Length438
- Mass (Da)47,275
- Last updated2007-01-23 v3
- Checksum48EA499055C9DE84
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF254643 EMBL· GenBank· DDBJ | AAK51201.1 EMBL· GenBank· DDBJ | mRNA |