The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.Kenmochi N., Suzuki T., Uechi T., Magoori M., Kuniba M., Higa S., Watanabe K., Tanaka T.View abstractCited forNUCLEOTIDE SEQUENCECategoriesSequencesSourceUniProtKB unreviewed (TrEMBL)PubMedEurope PMCGenomics 77:65-70 (2001)Cited in2711
The role of lysine acetylation in the function of mitochondrial ribosomal protein L12.Paluch K.V., Platz K.R., Rudisel E.J., Erdmann R.R., Laurin T.R., Dittenhafer-Reed K.E.View abstractAnnotationThe role of lysine acetylation in the function of mitochondrial ribosomal protein L12.SourceGeneRif: 6182PubMedEurope PMCProteins 92:583-592 (2024)Mapped to4
The m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12.Sun Y., Liu Y., Wang P., Chang L., Huang J.View abstractAnnotationThe m6A Reader YTHDC2 Suppresses Lung Adenocarcinoma Tumorigenesis by Destabilizing MRPL12.SourceGeneRif: 6182PubMedEurope PMCMol Biotechnol 66:1051-1061 (2024)Mapped to6
Mitochondrial ribosomal protein L12 potentiates hepatocellular carcinoma by regulating mitochondrial biogenesis and metabolic reprogramming.Ji X., Yang Z., Li C., Zhu S., Zhang Y., Xue F., Sun S., Fu T., Ding C.[...], Wan Q.View abstractAnnotationMitochondrial ribosomal protein L12 potentiates hepatocellular carcinoma by regulating mitochondrial biogenesis and metabolic reprogramming.SourceGeneRif: 6182PubMedEurope PMCMetabolism 152:155761-155761 (2024)Mapped to4
CUL3 induces mitochondrial dysfunction via MRPL12 ubiquitination in renal tubular epithelial cells.Ji X., Yang X., Gu X., Chu L., Sun S., Sun J., Song P., Mu Q., Wang Y.[...], Wan Q.View abstractAnnotationCUL3 induces mitochondrial dysfunction via MRPL12 ubiquitination in renal tubular epithelial cells.SourceGeneRif: 6182PubMedEurope PMCFEBS J 290:5340-5352 (2023)Mapped to8
MRPL12 Acts as A Novel Prognostic Biomarker Involved in Immune Cell Infiltration and Tumor Progression of Lung Adenocarcinoma.Hu Y., Liu Y., Ma C., Ai K.View abstractAnnotationMRPL12 Acts as A Novel Prognostic Biomarker Involved in Immune Cell Infiltration and Tumor Progression of Lung Adenocarcinoma.CategoriesFunctionSourceGeneRif: 6182PubMedEurope PMCInt J Mol Sci 24:2762-2762 (2023)Mapped to4
Transcription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.Gu X., Liu Y., Wang N., Zhen J., Zhang B., Hou S., Cui Z., Wan Q., Feng H.View abstractAnnotationTranscription of MRPL12 regulated by Nrf2 contributes to the mitochondrial dysfunction in diabetic kidney disease.CategoriesFunction, Subcellular LocationSourceGeneRif: 6182PubMedEurope PMCFree Radic Biol Med 164:329-340 (2021)Mapped to11
Mitochondrial Ribosomal Protein L12 Is Required for POLRMT Stability and Exists as Two Forms Generated by Alternative Proteolysis during Import.Nouws J., Goswami A.V., Bestwick M., McCann B.J., Surovtseva Y.V., Shadel G.S.View abstractAnnotationknock-down of MRPL12 by RNA interference results in instability of POLRMT.CategoriesFunctionSourceGeneRif: 6182PubMedEurope PMCJ Biol Chem 291:989-997 (2016)Mapped to9
Mutations in mitochondrial ribosomal protein MRPL12 leads to growth retardation, neurological deterioration and mitochondrial translation deficiency.Serre V., Rozanska A., Beinat M., Chretien D., Boddaert N., Munnich A., Roetig A., Chrzanowska-Lightowlers Z.M.View abstractAnnotationThis mutation resulted in a decreased steady-state level of MRPL12 protein.CategoriesSequencesSourceGeneRif: 6182PubMedEurope PMCBiochim. Biophys. Acta 1832:1304-1312 (2013)Cited in1Mapped to3
Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.Hendrickson S.L., Lautenberger J.A., Chinn L.W., Malasky M., Sezgin E., Kingsley L.A., Goedert J.J., Kirk G.D., Gomperts E.D.[...], O'Brien S.J.View abstractAnnotationObservational study of gene-disease association. (HuGE Navigator)CategoriesFunctionSourceGeneRif: 6182PubMedEurope PMCPLoS One 5:e12862-e12862 (2010)Mapped to99+
Human mitochondrial ribosomal protein MRPL12 interacts directly with mitochondrial RNA polymerase to modulate mitochondrial gene expression.Wang Z., Cotney J., Shadel G.S.View abstractAnnotationthe MRPL12 interaction with POLRMT is likely part of a novel regulatory mechanism that coordinates mitochondrial transcription with translationCategoriesInteractionSourceGeneRif: 6182PubMedEurope PMCJ Biol Chem 282:12610-12618 (2007)Mapped to8