These four variants were tested for association with mood disorder diagnosis or antidepressant response in a family study of depression but no significant associations were observed; Observational study of gene-disease association gene-environment interaction and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Hes6 overexpression using a retroviral vector led to a decrease in Hes1 levels an increase in beta-cell transcription factors and partial restoration of insulin expression
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