Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals.Ricotta D., Conner S.D., Schmid S.L., von Figura K., Honing S.View abstractCited forFUNCTION, PHOSPHORYLATION AT THR-156CategoriesFunction, PTM / ProcessingSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Cell Biol. 156:791-795 (2002)Cited in3Mapped to19
Adaptor protein complexes as the key regulators of protein sorting in the post-Golgi network.Nakatsu F., Ohno H.View abstractCited forFUNCTION OF THE AP-2 COMPLEX IN CLATHRIN-MEDIATED ENDOCYTOSISCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCCell Struct. Funct. 28:419-429 (2003)Cited in14
Clathrin-mediated endocytosis in AP-2-depleted cells.Motley A., Bright N.A., Seaman M.N.J., Robinson M.S.View abstractCited forFUNCTION IN CLATHRIN-MEDIATED ENDOCYTOSISCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Cell Biol. 162:909-918 (2003)Cited in1Mapped to11
Endocytosis of the viral chemokine receptor US28 does not require beta- arrestins but is dependent on the clathrin-mediated pathway.Fraile-Ramos A., Kohout T.A., Waldhoer M., Marsh M.View abstractCited forFUNCTION IN CLATHRIN-MEDIATED ENDOCYTOSISCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCTraffic 4:243-253 (2003)Cited in1
Adaptors for clathrin coats: structure and function.Owen D.J., Collins B.M., Evans P.R.View abstractCited forFUNCTION OF THE AP-2 COMPLEX IN CLATHRIN-MEDIATED ENDOCYTOSISCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAnnu. Rev. Cell Dev. Biol. 20:153-191 (2004)Cited in14Mapped to15
Analysis of clathrin-mediated endocytosis of epidermal growth factor receptor by RNA interference.Huang F., Khvorova A., Marshall W., Sorkin A.View abstractCited forFUNCTION IN CLATHRIN-MEDIATED ENDOCYTOSISCategoriesFunctionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Biol. Chem. 279:16657-16661 (2004)Cited in2Mapped to20
Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization.Paing M.M., Johnston C.A., Siderovski D.P., Trejo J.View abstractCited forFUNCTION IN RECEPTOR INTERNALIZATION, INTERACTION WITH F2RCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCMol. Cell. Biol. 26:3231-3242 (2006)Cited in1Mapped to9
The adaptor complex AP-2 regulates post-endocytic trafficking through the non-clathrin Arf6-dependent endocytic pathway.Lau A.W., Chou M.M.View abstractCited forFUNCTION OF THE AP-2 COMPLEX IN NON-CLATHRIN-DEPENDENT ENDOCYTOSISCategoriesFunction, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Cell Sci. 121:4008-4017 (2008)Cited in5Mapped to3
Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.Marcello E., Saraceno C., Musardo S., Vara H., de la Fuente A.G., Pelucchi S., Di Marino D., Borroni B., Tramontano A.[...], Di Luca M.View abstractCited forFUNCTION, INTERACTION WITH ADAM10, TISSUE SPECIFICITYCategoriesFunction, Expression, InteractionSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCJ. Clin. Invest. 123:2523-2538 (2013)Cited in13Mapped to44
A Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy.EuroEPINOMICS-RES Consortium, GRIN ConsortiumHelbig I., Lopez-Hernandez T., Shor O., Galer P., Ganesan S., Pendziwiat M., Rademacher A., Ellis C.A., Huempfer N.[...], Weber Y.G.View abstractCited forVARIANT MRD60 TRP-170, CHARACTERIZATION OF VARIANT MRD60 TRP-170, FUNCTION, SUBCELLULAR LOCATION, INVOLVEMENT IN MRD60CategoriesFunction, Sequences, Disease & Variants, Subcellular LocationSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCAm. J. Hum. Genet. 104:1060-1072 (2019)Cited in1Mapped to7
A structural explanation for the recognition of tyrosine-based endocytotic signals.Owen D.J., Evans P.R.View abstractAnnotationPathwayCategoriesStructure, FunctionSourcePDB: 1H6E, Reactome: R-HSA-182227PubMedEurope PMCScience 282:1327-1332 (1998)Cited in11Mapped to22
Crystal structure of the amphiphysin-2 SH3 domain and its role in the prevention of dynamin ring formation.Owen D.J., Wigge P., Vallis Y., Moore J.D.A., Evans P.R., McMahon H.T.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585, Reactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCEMBO J. 17:5273-5285 (1998)Cited in1Mapped to99+
Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.Chen H., Fre S., Slepnev V.I., Capua M.R., Takei K., Butler M.H., Di Fiore P.P., De Camilli P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585PubMedEurope PMCNature 394:793-797 (1998)Cited in2Mapped to33
The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway.Kamiguchi H., Long K.E., Pendergast M., Schaefer A.W., Rapoport I., Kirchhausen T., Lemmon V.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585PubMedEurope PMCJ Neurosci 18:5311-5321 (1998)Mapped to12
Dynamin undergoes a GTP-dependent conformational change causing vesiculation.Sweitzer S.M., Hinshaw J.E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585, Reactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCCell 93:1021-1029 (1998)Mapped to99+
Synaptojanin 1: localization on coated endocytic intermediates in nerve terminals and interaction of its 170 kDa isoform with Eps15.Haffner C., Takei K., Chen H., Ringstad N., Hudson A., Butler M.H., Salcini A.E., Di Fiore P.P., De Camilli P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585, Reactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCFEBS Lett. 419:175-180 (1997)Cited in2Mapped to99+
A novel role for Rab5-GDI in ligand sequestration into clathrin-coated pits.McLauchlan H., Newell J., Morrice N., Osborne A., West M., Smythe E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCCurr Biol 8:34-45 (1998)Mapped to99+
Decreased endosomal delivery of major histocompatibility complex class II- invariant chain complexes in dynamin-deficient cells.Wang K., Peterson P.A., Karlsson L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585, Reactome: R-HSA-6784828PubMedEurope PMCJ Biol Chem 272:17055-17060 (1997)Mapped to23
Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain.Goodman O.B. Jr., Krupnick J.G., Gurevich V.V., Benovic J.L., Keen J.H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-8856805PubMedEurope PMCJ Biol Chem 272:15017-15022 (1997)Mapped to33
Auxilin-induced interaction of the molecular chaperone Hsc70 with clathrin baskets.Barouch W., Prasad K., Greene L., Eisenberg E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCBiochemistry 36:4303-4308 (1997)Mapped to99+
Synaptic vesicle endocytosis impaired by disruption of dynamin-SH3 domain interactions.Shupliakov O., Low P., Grabs D., Gad H., Chen H., David C., Takei K., De Camilli P., Brodin L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585, Reactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCScience 276:259-263 (1997)Mapped to99+
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2- adrenergic receptor.Goodman O.B. Jr., Krupnick J.G., Santini F., Gurevich V.V., Penn R.B., Gagnon A.W., Keen J.H., Benovic J.L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-8856805PubMedEurope PMCNature 383:447-450 (1996)Mapped to33
Involvement of p90rsk in neurite outgrowth mediated by the cell adhesion molecule L1.Wong E.V., Schaefer A.W., Landreth G., Lemmon V.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585PubMedEurope PMCJ Biol Chem 271:18217-18223 (1996)Mapped to16
A role of amphiphysin in synaptic vesicle endocytosis suggested by its binding to dynamin in nerve terminals.David C., McPherson P.S., Mundigl O., de Camilli P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-167585, Reactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCProc Natl Acad Sci U S A 93:331-335 (1996)Mapped to99+
Role of auxilin in uncoating clathrin-coated vesicles.Ungewickell E., Ungewickell H., Holstein S.E., Lindner R., Prasad K., Barouch W., Martin B., Greene L.E., Eisenberg E.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-182227, Reactome: R-HSA-8856805PubMedEurope PMCNature 378:632-635 (1995)Cited in3Mapped to99+