Complete sequencing and characterization of 21,243 full-length human cDNAs.Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H.[...], Sugano S.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)TissueTeratocarcinomaCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNat. Genet. 36:40-45 (2004)Cited in99+99+
The DNA sequence and biological annotation of human chromosome 1.Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A., Scott C.E., Howe K.L., Woodfine K.[...], Bentley D.R.View abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]CategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCNature 441:315-321 (2006)Cited in99+99+
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).The MGC Project TeamView abstractCited forNUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT ASP-76TissueLiverCategoriesSequencesSourceUniProtKB reviewed (Swiss-Prot)PubMedEurope PMCGenome Res. 14:2121-2127 (2004)Cited in99+99+
Transcriptional repression by RING finger protein TIF1 beta that interacts with the KRAB repressor domain of KOX1.Moosmann P.R., Georgiev O., le Douarin B., Bourquin J.-P., Schaffner W.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCNucleic Acids Res. 24:4859-4867 (1996)Cited in1Mapped to60
KAP-1, a novel corepressor for the highly conserved KRAB repression domain.Friedman J.R., Fredericks W.J., Jensen D.E., Speicher D.W., Huang X.-P., Neilson E.G., Rauscher F.J. IIIView abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCGenes Dev. 10:2067-2078 (1996)Cited in1Mapped to99+
Kruppel-associated boxes are potent transcriptional repression domains.Margolin J.F., Friedman J.R., Meyer W.K., Vissing H., Thiesen H.J., Rauscher F.J.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCProc Natl Acad Sci U S A 91:4509-4513 (1994)Mapped to99+
Genetic features and genomic targets of human KRAB-zinc finger proteins.de Tribolet-Hardy J., Thorball C.W., Forey R., Planet E., Duc J., Coudray A., Khubieh B., Offner S., Pulver C.[...], Trono D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCGenome Res 33:1409-1423 (2023)Mapped to58
Potential role of KRAB-ZFP binding and transcriptional states on DNA methylation of retroelements in human male germ cells.Fukuda K., Makino Y., Kaneko S., Shimura C., Okada Y., Ichiyanagi K., Shinkai Y.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCElife 11:e76822-e76822 (2022)Mapped to58
Mosaic cis-regulatory evolution drives transcriptional partitioning of HERVH endogenous retrovirus in the human embryo.Carter T.A., Singh M., Dumbovic G., Chobirko J.D., Rinn J.L., Feschotte C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCElife 11:e76257-e76257 (2022)Mapped to58
KAP1 is an antiparallel dimer with a functional asymmetry.Fonti G., Marcaida M.J., Bryan L.C., Trager S., Kalantzi A.S., Helleboid P.J., Demurtas D., Tully M.D., Grudinin S.[...], Dal Peraro M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCLife Sci Alliance 2:e201900349-e201900349 (2019)Mapped to61
Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing.Stoll G.A., Oda S.I., Chong Z.S., Yu M., McLaughlin S.H., Modis Y.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCProc Natl Acad Sci U S A 116:15042-15051 (2019)Mapped to62
A Dissection of Oligomerization by the TRIM28 Tripartite Motif and the Interaction with Members of the Krab-ZFP Family.Sun Y., Keown J.R., Black M.M., Raclot C., Demarais N., Trono D., Turelli P., Goldstone D.C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCJ Mol Biol 431:2511-2527 (2019)Mapped to60
Hominoid-Specific Transposable Elements and KZFPs Facilitate Human Embryonic Genome Activation and Control Transcription in Naive Human ESCs.Pontis J., Planet E., Offner S., Turelli P., Duc J., Coudray A., Theunissen T.W., Jaenisch R., Trono D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCCell Stem Cell 24:724-735.e5 (2019)Mapped to58
KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks.Imbeault M., Helleboid P.Y., Trono D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCNature 543:550-554 (2017)Mapped to59
Multiparameter functional diversity of human C2H2 zinc finger proteins.Schmitges F.W., Radovani E., Najafabadi H.S., Barazandeh M., Campitelli L.F., Yin Y., Jolma A., Zhong G., Guo H.[...], Hughes T.R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCGenome Res 26:1742-1752 (2016)Mapped to59
Characterization of the Enzymatic Activity of SETDB1 and Its 1:1 Complex with ATF7IP.Basavapathruni A., Gureasko J., Porter Scott M., Hermans W., Godbole A., Leland P.A., Boriack-Sjodin P.A., Wigle T.J., Copeland R.A., Riera T.V.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCBiochemistry 55:1645-1651 (2016)Mapped to67
Systematic identification of factors for provirus silencing in embryonic stem cells.Yang B.X., El Farran C.A., Guo H.C., Yu T., Fang H.T., Wang H.F., Schlesinger S., Seah Y.F., Goh G.Y.[...], Loh Y.H.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCCell 163:230-245 (2015)Mapped to61
C2H2 zinc finger proteins greatly expand the human regulatory lexicon.Najafabadi H.S., Mnaimneh S., Schmitges F.W., Garton M., Lam K.N., Yang A., Albu M., Weirauch M.T., Radovani E.[...], Hughes T.R.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCNat Biotechnol 33:555-562 (2015)Mapped to58
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons.Jacobs F.M., Greenberg D., Nguyen N., Haeussler M., Ewing A.D., Katzman S., Paten B., Salama S.R., Haussler D.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCNature 516:242-245 (2014)Cited in2Mapped to61
Zinc finger-DNA recognition: crystal structure of a Zif268-DNA complex at 2.1 A.Pavletich N.P., Pabo C.O.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCScience 252:809-817 (1991)Cited in1Mapped to58
Embryonic stem cells use ZFP809 to silence retroviral DNAs.Wolf D., Goff S.P.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCNature 458:1201-1204 (2009)Cited in1Mapped to66
PHD domain-mediated E3 ligase activity directs intramolecular sumoylation of an adjacent bromodomain required for gene silencing.Ivanov A.V., Peng H., Yurchenko V., Yap K.L., Negorev D.G., Schultz D.C., Psulkowski E., Fredericks W.J., White D.E.[...], Rauscher F.J. IIIView abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCMol. Cell 28:823-837 (2007)Cited in1Mapped to74
Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain.Mascle X.H., Germain-Desprez D., Huynh P., Estephan P., Aubry M.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCJ Biol Chem 282:10190-10202 (2007)Mapped to64
The KAP1 corepressor functions to coordinate the assembly of de novo HP1- demarcated microenvironments of heterochromatin required for KRAB zinc finger protein-mediated transcriptional repression.Sripathy S.P., Stevens J., Schultz D.C.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCMol Cell Biol 26:8623-8638 (2006)Mapped to63
A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors.Huntley S., Baggott D.M., Hamilton A.T., Tran-Gyamfi M., Yang S., Kim J., Gordon L., Branscomb E., Stubbs L.View abstractAnnotationPathwayCategoriesFunctionSourceReactome: R-HSA-2248869PubMedEurope PMCGenome Res 16:669-677 (2006)Mapped to99+