Q95Q34 · RIOK2_CAEEL

  • Protein
    Serine/threonine-protein kinase RIO2
  • Gene
    riok-2
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    5/5

Function

function

Required for larval development.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site123ATP (UniProtKB | ChEBI)
Active site228Proton acceptor

GO annotations

AspectTerm
Cellular Componentcytosol
Cellular Componentnucleus
Cellular Componentpreribosome, small subunit precursor
Molecular FunctionATP binding
Molecular Functionmetal ion binding
Molecular Functionprotein kinase activity
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processmaturation of SSU-rRNA
Biological Processnematode larval development

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Serine/threonine-protein kinase RIO2
  • EC number

Gene names

    • Name
      riok-2
    • ORF names
      Y105E8B.3

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q95Q34

Proteomes

Organism-specific databases

Phenotypes & Variants

Disruption phenotype

RNAi-mediated knockdown causes early larval arrest. In adults, results in no obvious phenotype.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00004346061-529Serine/threonine-protein kinase RIO2

Proteomic databases

Expression

Tissue specificity

Expressed in pharynx (metacorpus and posterior bulbus). Expression is restricted to adult stage.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain97-273Protein kinase
Region331-366Disordered
Compositional bias336-363Acidic residues
Compositional bias411-430Basic and acidic residues
Region411-452Disordered
Compositional bias431-450Acidic residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    529
  • Mass (Da)
    60,485
  • Last updated
    2003-06-01 v2
  • Checksum
    0671C8143EFB8D21
MGRMNVSMMRYLEGDHFRVLIAVEMGMKNHEVVPLALVSAIAGIHRGGVARTLNDLCKHSLVAFERSKKFDGYRLTIRGYDYLALRALCSREVVGSVGNQIGIGKESDVYVGGDPELNDLCLKFHRLGRTSFRKIKEKRDYHKKRKSASWLYLSRLAAAKEFAFLKALQERGFPVPKAVDVCRHLVVMQLVVGQTLCNVTHVEDAGALYDRLMALIVKMARHGVIHGDFNEFNLIMLEDERIVMIDFPQMVSIDHPNAEYYFDRDVTCVRTFFKRKFDYESEDWPKFDEVERKGNMDVLLEASGFTKKMALDLNKAYDEGDFLAHCEQELRNRQEEDLGEDEDDSDDSKSMEDIQEEPEDLEKDHEELQAQENTVKQQKIVLSQTTRFTDWLSDATNQLEAVDLDALKSEEGYKDIELPPEDFKRPADSENDDENDEDEEEGEEEDADGHVAVEEQVAKVVKKKRVPSGARSVASSAATFTAEDVKRRLALDRKRNKEKIRLKVKGKQSAVGRNRKDNKDVIAEYAGWI

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias336-363Acidic residues
Compositional bias411-430Basic and acidic residues
Compositional bias431-450Acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BX284601
EMBL· GenBank· DDBJ
CAC70109.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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