Q95529 · Q95529_PANTR

Function

function

Involved in the presentation of foreign antigens to the immune system.

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell surface
Cellular Componentearly endosome membrane
Cellular ComponentER to Golgi transport vesicle membrane
Cellular Componentlumenal side of endoplasmic reticulum membrane
Cellular ComponentMHC class I protein complex
Cellular Componentphagocytic vesicle membrane
Cellular Componentrecycling endosome membrane
Biological Processantigen processing and presentation of peptide antigen via MHC class I
Biological Processimmune response

Keywords

  • Biological process

Names & Taxonomy

Protein names

  • Submitted names
    • Class I histocompatibility antigen

Gene names

    • Name
      HLA-B

Organism names

  • Taxonomic identifier
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Primates > Haplorrhini > Catarrhini > Hominidae > Pan

Accessions

  • Primary accession
    Q95529

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane300-324Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain.

TypeIDPosition(s)Description
Signal1-16
ChainPRO_500432151817-355

Keywords

Interaction

Subunit

Heterodimer of an alpha chain and a beta chain (beta-2-microglobulin).

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain201-287Ig-like
Region329-355Disordered
Compositional bias332-355Polar residues

Sequence similarities

Belongs to the MHC class I family.

Keywords

Family and domain databases

Sequence

  • Sequence status
    Fragment
  • Length
    355
  • Mass (Da)
    39,772
  • Last updated
    1997-02-01 v1
  • Checksum
    F474A2C3EEDC398A
VLLLLSAALALTETWAGSHSMRYFYTSVSRPGRGEPRFITVGYVDDTQFVRFDSDAASPRMEPRAPWIEQEGPEYWDRETRNMKASAQTDRENLRIALRYYNQSEAGSHIIQRMYGCDMGPDGRLLRGYYQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAARAAEQRRAYLEGTCVEWLRRYLENGKETLQRADPPKTHVTHHPISDHEATLRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPEGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWEPSSQSTIPIVGIVAGLAVLVVTVAVVAVVAAVLCRRKSSGGKGGSYSQAASSDSAQGSDVSLTA

Features

Showing features for non-terminal residue, compositional bias.

TypeIDPosition(s)Description
Non-terminal residue1
Compositional bias332-355Polar residues

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
U05580
EMBL· GenBank· DDBJ
AAA50183.1
EMBL· GenBank· DDBJ
mRNA

Similar Proteins

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