Q94IH5 · Q94IH5_MAIZE
- ProteinVacuolar cation/proton exchanger
- GeneZCAX2
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids410 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score2/5
Function
function
Vacuolar cation/proton exchanger (CAX). Translocates Ca2+ and other metal ions into vacuoles using the proton gradient formed by H+-ATPase and H+-pyrophosphatase.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | vacuolar membrane | |
Molecular Function | calcium:proton antiporter activity |
Keywords
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameVacuolar cation/proton exchanger
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > PACMAD clade > Panicoideae > Andropogonodae > Andropogoneae > Tripsacinae > Zea
Accessions
- Primary accessionQ94IH5
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 39-61 | Helical | ||||
Sequence: IVIFTSKLNLLMPFGPASIILHF | ||||||
Transmembrane | 68-86 | Helical | ||||
Sequence: LIFLFSMLGVTPLAERLGY | ||||||
Transmembrane | 98-120 | Helical | ||||
Sequence: TVGGLLNATFGNATEMIIAVYAL | ||||||
Transmembrane | 132-155 | Helical | ||||
Sequence: LLGSILSNMLLVMGCAFFAGGVVH | ||||||
Transmembrane | 167-190 | Helical | ||||
Sequence: AVVNSGLLLMAVMGLMFPAVLHFT | ||||||
Transmembrane | 202-221 | Helical | ||||
Sequence: ALSRFSSCIMLVAYASYLYF | ||||||
Transmembrane | 257-276 | Helical | ||||
Sequence: AVTWLAVLTLWVSFLSEYLV | ||||||
Transmembrane | 288-315 | Helical | ||||
Sequence: LPVAFISVILLPIVGNAAEHASAIMFAM | ||||||
Transmembrane | 321-346 | Helical | ||||
Sequence: ITLGVAIGSSTQISMFVIPFCVVIGW | ||||||
Transmembrane | 358-376 | Helical | ||||
Sequence: LFETATLFITVLVVAFMLQ | ||||||
Transmembrane | 382-403 | Helical | ||||
Sequence: YLKGLMLILCYLIVAASFFVHV |
Keywords
- Cellular component
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-24 | Disordered | ||||
Sequence: MGGFKVNSPQVPNGVSRPTVSSSW | ||||||
Compositional bias | 9-24 | Polar residues | ||||
Sequence: PQVPNGVSRPTVSSSW | ||||||
Domain | 68-223 | Sodium/calcium exchanger membrane region | ||||
Sequence: LIFLFSMLGVTPLAERLGYATEQLAIYTGPTVGGLLNATFGNATEMIIAVYALKNGMIRVVQQSLLGSILSNMLLVMGCAFFAGGVVHRNKDQIFSKATAVVNSGLLLMAVMGLMFPAVLHFTHSEVRQGASEVALSRFSSCIMLVAYASYLYFQL | ||||||
Domain | 258-399 | Sodium/calcium exchanger membrane region | ||||
Sequence: VTWLAVLTLWVSFLSEYLVNTIEGASDSLNLPVAFISVILLPIVGNAAEHASAIMFAMKDKLDITLGVAIGSSTQISMFVIPFCVVIGWMMGQRMDLNFQLFETATLFITVLVVAFMLQDGTANYLKGLMLILCYLIVAASF |
Sequence similarities
Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. Cation/proton exchanger (CAX) subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Length410
- Mass (Da)44,477
- Last updated2001-12-01 v1
- ChecksumEAB14FCEB3338D25
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 9-24 | Polar residues | ||||
Sequence: PQVPNGVSRPTVSSSW |