Q94BN2 · SPSY_ARATH

Function

Catalytic activity

Pathway

Amine and polyamine biosynthesis; spermine biosynthesis; spermine from spermidine: step 1/1.

Features

Showing features for binding site, active site.

135950100150200250300350
TypeIDPosition(s)Description
Binding site99S-adenosyl 3-(methylsulfanyl)propylamine (UniProtKB | ChEBI)
Binding site129spermidine (UniProtKB | ChEBI)
Binding site130S-adenosyl 3-(methylsulfanyl)propylamine (UniProtKB | ChEBI)
Binding site154spermidine (UniProtKB | ChEBI)
Binding site174S-adenosyl 3-(methylsulfanyl)propylamine (UniProtKB | ChEBI)
Binding site205-206S-adenosyl 3-(methylsulfanyl)propylamine (UniProtKB | ChEBI)
Active site224Proton acceptor
Binding site292putrescine (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcytosol
Molecular Functionspermidine synthase activity
Molecular Functionspermine synthase activity
Biological Processspermidine biosynthetic process
Biological Processspermine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Spermine synthase
  • EC number
  • Short names
    SPMSY
  • Alternative names
    • Spermidine aminopropyltransferase

Gene names

    • Name
      SPMS
    • Synonyms
      SPDS3
    • ORF names
      MFH8.5
    • Ordered locus names
      At5g53120

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q94BN2
  • Secondary accessions
    • B9DFL7
    • Q8LBG3
    • Q944S0
    • Q9FGM4

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003976731-359Spermine synthase

Proteomic databases

Expression

Tissue specificity

Expressed predominantly in stem internodes, flower buds and roots.

Induction

Up-regulated by abscisic acid and salt stress.

Gene expression databases

Interaction

Subunit

Heterodimer. Component of a multiprotein complex. Interacts with SPDSYN1 and SPDSYN2.

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntact
BINARY Q94BN2SPDSYN1 Q9ZUB34EBI-1770109, EBI-1770123
BINARY Q94BN2SPDSYN2 O486614EBI-1770109, EBI-1770100

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain53-304PABS

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q94BN2-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    359
  • Mass (Da)
    39,239
  • Last updated
    2001-12-01 v1
  • Checksum
    5251D28EBB98865D
MEGDVGIGLVCQNTMDGKASNGNGLEKTVPSCCLKAMACVPEDDAKCHSTVVSGWFSEPHPRSGKKGGKAVYFNNPMWPGEAHSLKVEKVLFKDKSDFQEVLVFESATYGKVLVLDGIVQLTEKDECAYQEMIAHLPLCSISSPKNVLVVGGGDGGVLREISRHSSVEVIDICEIDKMVIDVSKKFFPELAVGFDDPRVQLHIGDAAEFLRKSPEGKYDAIIVDSSDPVGPALALVEKPFFETLARALKPGGVLCNMAESMWLHTHLIEDMISICRQTFKSVHYAWSSVPTYPSGVIGFVLCSTEGPAVDFKNPINPIEKLDGAMTHKRELKFYNSDMHRAAFALPTFLRREVASLLAS

Computationally mapped potential isoform sequences

There are 2 potential isoforms mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1R7T3F8A0A1R7T3F8_ARATHSPDS3376
F4KJ05F4KJ05_ARATHSPDS3386

Sequence caution

The sequence AAM64782.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.
The sequence BAB08415.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict40in Ref. 4; BAH19534
Sequence conflict204in Ref. 5; AAM64782
Sequence conflict224in Ref. 3; AAL11565

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB025622
EMBL· GenBank· DDBJ
BAB08415.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002688
EMBL· GenBank· DDBJ
AED96305.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED96306.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED96307.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED96308.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002688
EMBL· GenBank· DDBJ
AED96309.1
EMBL· GenBank· DDBJ
Genomic DNA
AF424571
EMBL· GenBank· DDBJ
AAL11565.1
EMBL· GenBank· DDBJ
mRNA
AY040013
EMBL· GenBank· DDBJ
AAK64170.1
EMBL· GenBank· DDBJ
mRNA
AY079367
EMBL· GenBank· DDBJ
AAL85098.1
EMBL· GenBank· DDBJ
mRNA
BT000742
EMBL· GenBank· DDBJ
AAN31883.1
EMBL· GenBank· DDBJ
mRNA
AK316822
EMBL· GenBank· DDBJ
BAH19534.1
EMBL· GenBank· DDBJ
mRNA
AY087226
EMBL· GenBank· DDBJ
AAM64782.1
EMBL· GenBank· DDBJ
mRNA Different initiation

Genome annotation databases

Similar Proteins

Disclaimer

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