Q94AX5 · PAM71_ARATH
- ProteinProtein PAM71, chloroplastic
- GenePAM71
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids370 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Mn2+/H+ exchanger, which transport Mn2+from the chloroplast stroma into the acidic thylakoid lumen (PubMed:27020959).
Might be a chloroplast-localized Ca2+/H+ antiporter (PubMed:27302341).
Regulates Ca2+, Mn2+ and pH homeostasis (PubMed:27302341).
Required for chloroplast development (PubMed:27302341).
Might be a chloroplast-localized Ca2+/H+ antiporter (PubMed:27302341).
Regulates Ca2+, Mn2+ and pH homeostasis (PubMed:27302341).
Required for chloroplast development (PubMed:27302341).
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | chloroplast membrane | |
Cellular Component | chloroplast thylakoid | |
Cellular Component | chloroplast thylakoid membrane | |
Molecular Function | calcium ion transmembrane transporter activity | |
Molecular Function | magnesium ion transmembrane transporter activity | |
Molecular Function | manganese ion transmembrane transporter activity | |
Biological Process | calcium ion transmembrane transport | |
Biological Process | calcium ion transport | |
Biological Process | calcium-mediated signaling | |
Biological Process | photosystem II oxygen evolving complex assembly |
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameProtein PAM71, chloroplastic
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ94AX5
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Plastid, chloroplast membrane ; Multi-pass membrane protein
Features
Showing features for topological domain, transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Topological domain | 74-113 | Stromal | ||||
Sequence: CFQRNDAACYLEKAESEEHDRNLDVLVESSIAHSRREIQR | ||||||
Transmembrane | 114-134 | Helical | ||||
Sequence: VLMFLAVSGSVALLGTDPAFA | ||||||
Topological domain | 135-161 | Lumenal, thylakoid | ||||
Sequence: ASSIPNVTQSLVTSFGDLGDISSGFAS | ||||||
Transmembrane | 162-182 | Helical | ||||
Sequence: AFLLIFFSELGDKTFFIAALL | ||||||
Topological domain | 183-188 | Stromal | ||||
Sequence: AARNSA | ||||||
Transmembrane | 189-209 | Helical | ||||
Sequence: ATVFVGTFGALGIMTIISVVL | ||||||
Topological domain | 210-228 | Lumenal, thylakoid | ||||
Sequence: GRTFHYVDEVLPFRFGGTD | ||||||
Transmembrane | 229-249 | Helical | ||||
Sequence: LPIDDIAAVCLLVYFGVSTLL | ||||||
Topological domain | 250-275 | Stromal | ||||
Sequence: DAVSDEGKADEEQKEAELAVSELSGN | ||||||
Transmembrane | 276-296 | Helical | ||||
Sequence: GAGIVAAANTIISTFALVFVA | ||||||
Topological domain | 297-315 | Lumenal, thylakoid | ||||
Sequence: EWGDKSFFSTIALAAASSP | ||||||
Transmembrane | 316-336 | Helical | ||||
Sequence: LGVIAGALAGHGAATLLAVLG | ||||||
Topological domain | 337-348 | Stromal | ||||
Sequence: GSLLGNFLSEKA | ||||||
Transmembrane | 349-369 | Helical | ||||
Sequence: IAYVGGVLFLVFAAVTVAEIV | ||||||
Topological domain | 370 | Lumenal, thylakoid | ||||
Sequence: T |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Defects in photosynthesis and reduced growth rate (PubMed:27020959, PubMed:27302341).
Pale yellow leaves with reduced PSII activity (PubMed:27302341).
Altered Ca2+ and Mn2+ partitioning in chloroplasts and reduced Mn2+ binding to PSII (PubMed:27020959).
Pale yellow leaves with reduced PSII activity (PubMed:27302341).
Altered Ca2+ and Mn2+ partitioning in chloroplasts and reduced Mn2+ binding to PSII (PubMed:27020959).
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 54 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-73 | Chloroplast | ||||
Sequence: MLSLNLSESLRIPFQNPRPPKSDFSSTSSSPSSSSRRCVSAYPIPIGFSVRNQYFSRCLTQLRRNESQQLGFR | ||||||
Chain | PRO_0000398764 | 74-370 | Protein PAM71, chloroplastic | |||
Sequence: CFQRNDAACYLEKAESEEHDRNLDVLVESSIAHSRREIQRVLMFLAVSGSVALLGTDPAFAASSIPNVTQSLVTSFGDLGDISSGFASAFLLIFFSELGDKTFFIAALLAARNSAATVFVGTFGALGIMTIISVVLGRTFHYVDEVLPFRFGGTDLPIDDIAAVCLLVYFGVSTLLDAVSDEGKADEEQKEAELAVSELSGNGAGIVAAANTIISTFALVFVAEWGDKSFFSTIALAAASSPLGVIAGALAGHGAATLLAVLGGSLLGNFLSEKAIAYVGGVLFLVFAAVTVAEIVT |
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-38 | Disordered | ||||
Sequence: MLSLNLSESLRIPFQNPRPPKSDFSSTSSSPSSSSRRC | ||||||
Compositional bias | 19-38 | Polar residues | ||||
Sequence: PPKSDFSSTSSSPSSSSRRC |
Sequence similarities
Belongs to the GDT1 family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length370
- Mass (Da)39,074
- Last updated2010-10-05 v2
- Checksum5D3FF0E824889BE7
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 19-38 | Polar residues | ||||
Sequence: PPKSDFSSTSSSPSSSSRRC | ||||||
Sequence conflict | 54 | in Ref. 3; AAN28814/AAK73997 | ||||
Sequence: Y → S |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC007764 EMBL· GenBank· DDBJ | AAF24562.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002684 EMBL· GenBank· DDBJ | AEE34202.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY045639 EMBL· GenBank· DDBJ | AAK73997.1 EMBL· GenBank· DDBJ | mRNA | ||
AY143875 EMBL· GenBank· DDBJ | AAN28814.1 EMBL· GenBank· DDBJ | mRNA |