Q94AX5 · PAM71_ARATH

Function

function

Mn2+/H+ exchanger, which transport Mn2+from the chloroplast stroma into the acidic thylakoid lumen (PubMed:27020959).
Might be a chloroplast-localized Ca2+/H+ antiporter (PubMed:27302341).
Regulates Ca2+, Mn2+ and pH homeostasis (PubMed:27302341).
Required for chloroplast development (PubMed:27302341).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentchloroplast membrane
Cellular Componentchloroplast thylakoid
Cellular Componentchloroplast thylakoid membrane
Molecular Functioncalcium ion transmembrane transporter activity
Molecular Functionmagnesium ion transmembrane transporter activity
Molecular Functionmanganese ion transmembrane transporter activity
Biological Processcalcium ion transmembrane transport
Biological Processcalcium ion transport
Biological Processcalcium-mediated signaling
Biological Processphotosystem II oxygen evolving complex assembly

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Protein PAM71, chloroplastic
  • Alternative names
    • CA(2+)/H(+) ANTIPORTER 1
    • GDT1-like protein 1
    • PHOTOSYNTHESIS AFFECTED MUTANT71

Gene names

    • Name
      PAM71
    • Synonyms
      CCHA1
    • ORF names
      F22C12.9
    • Ordered locus names
      At1g64150

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q94AX5
  • Secondary accessions
    • Q9SH65

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain74-113Stromal
Transmembrane114-134Helical
Topological domain135-161Lumenal, thylakoid
Transmembrane162-182Helical
Topological domain183-188Stromal
Transmembrane189-209Helical
Topological domain210-228Lumenal, thylakoid
Transmembrane229-249Helical
Topological domain250-275Stromal
Transmembrane276-296Helical
Topological domain297-315Lumenal, thylakoid
Transmembrane316-336Helical
Topological domain337-348Stromal
Transmembrane349-369Helical
Topological domain370Lumenal, thylakoid

Keywords

Phenotypes & Variants

Disruption phenotype

Defects in photosynthesis and reduced growth rate (PubMed:27020959, PubMed:27302341).
Pale yellow leaves with reduced PSII activity (PubMed:27302341).
Altered Ca2+ and Mn2+ partitioning in chloroplasts and reduced Mn2+ binding to PSII (PubMed:27020959).

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 54 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for transit peptide, chain.

TypeIDPosition(s)Description
Transit peptide1-73Chloroplast
ChainPRO_000039876474-370Protein PAM71, chloroplastic

Proteomic databases

Expression

Gene expression databases

Interaction

Subunit

Homodimer.

Protein-protein interaction databases

Family & Domains

Features

Showing features for region, compositional bias.

TypeIDPosition(s)Description
Region1-38Disordered
Compositional bias19-38Polar residues

Sequence similarities

Belongs to the GDT1 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    370
  • Mass (Da)
    39,074
  • Last updated
    2010-10-05 v2
  • Checksum
    5D3FF0E824889BE7
MLSLNLSESLRIPFQNPRPPKSDFSSTSSSPSSSSRRCVSAYPIPIGFSVRNQYFSRCLTQLRRNESQQLGFRCFQRNDAACYLEKAESEEHDRNLDVLVESSIAHSRREIQRVLMFLAVSGSVALLGTDPAFAASSIPNVTQSLVTSFGDLGDISSGFASAFLLIFFSELGDKTFFIAALLAARNSAATVFVGTFGALGIMTIISVVLGRTFHYVDEVLPFRFGGTDLPIDDIAAVCLLVYFGVSTLLDAVSDEGKADEEQKEAELAVSELSGNGAGIVAAANTIISTFALVFVAEWGDKSFFSTIALAAASSPLGVIAGALAGHGAATLLAVLGGSLLGNFLSEKAIAYVGGVLFLVFAAVTVAEIVT

Sequence caution

The sequence AAF24562.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for compositional bias, sequence conflict.

TypeIDPosition(s)Description
Compositional bias19-38Polar residues
Sequence conflict54in Ref. 3; AAN28814/AAK73997

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC007764
EMBL· GenBank· DDBJ
AAF24562.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002684
EMBL· GenBank· DDBJ
AEE34202.1
EMBL· GenBank· DDBJ
Genomic DNA
AY045639
EMBL· GenBank· DDBJ
AAK73997.1
EMBL· GenBank· DDBJ
mRNA
AY143875
EMBL· GenBank· DDBJ
AAN28814.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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