Q949U1 · C79F1_ARATH

Function

function

Catalyzes the conversion of the short chain elongated methionines di-, tri-, and tetrahomomethionine to their respective aldoximes 5-methylthiopentanaldoxime, 6-methylthiohexanaldoxime, and 7-methylheptanaldoxime.

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
34 μMdihomomethionine
37 μMtrihomomethionine
194 μMtetrahomomethionine
216 μMpentahomomethionine
74 μMhexahomomethionine

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentendoplasmic reticulum membrane
Cellular Componentnucleus
Molecular FunctionCYP79F1 dihomomethionine monooxygenase activity
Molecular FunctionCYP79F1 trihomomethionine monooxygenase activity
Molecular Functionheme binding
Molecular Functioniron ion binding
Molecular Functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
Biological Processglucosinolate biosynthetic process
Biological Processresponse to insect

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dihomomethionine N-hydroxylase
  • EC number
  • Alternative names
    • Cytochrome P450 79F1
    • Protein BUSHY 1
    • Protein SUPERSHOOT 1
    • Trihomomethionine N-hydroxylase

Gene names

    • Name
      CYP79F1
    • Synonyms
      BUS1, SPS1
    • ORF names
      F3O9.21
    • Ordered locus names
      At1g16410

Organism names

  • Taxonomic identifier
  • Strains
    • cv. Columbia
    • cv. Ag-0
    • cv. An-1
    • cv. Br-0
    • cv. C24
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q949U1
  • Secondary accessions
    • A5YZH1
    • A5YZH3
    • A5YZH4
    • A5YZH6
    • A5YZH9

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane8-28Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Plants have a bushy phenotype with crinkled leaves and retarded vascularization.

Features

Showing features for natural variant.

TypeIDPosition(s)Description
Natural variant43in strain: cv. Ag-0, cv. Br-0, cv. C24, cv. Ct-1, cv. Edi-0, cv. Kas-1, cv. Kin-0, cv. Landsberg erecta, cv. Ll-0, cv. Lz-0, cv. Ms-0, cv. Mt-0, cv. Nd-1, cv. Nok-3, cv. Oy-0, cv. Sorbo, cv. Van-0, cv. Wa-1 and cv. Wassilewskija
Natural variant83in strain: cv. Se-0
Natural variant120in strain: cv. Br-0 and cv. Mt-0
Natural variant154in strain: cv. Ag-0, cv. Cvi-1, cv. Edi-0, cv. Ll-0 and cv. Nok-3
Natural variant158in strain: cv. Ag-0, cv. Br-0, cv. Cvi-1, cv. Edi-0, cv. Ll-0, cv. Lz-0, cv. Mt-0, cv. Nok-3 and cv. Van-0
Natural variant159in strain: cv. Nd-1
Natural variant161in strain: cv. Lz-0 and cv. Van-0
Natural variant192in strain: cv. Kin-0
Natural variant222in strain: cv. Ll-0

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 46 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003158431-538Dihomomethionine N-hydroxylase

Proteomic databases

Expression

Tissue specificity

Highly expressed in cotyledons, leaves, stems and siliques. Detected in flowers and lateral roots, but not in the main root. Expressed only in the vascular bundles in apical plant parts.

Induction

By methyl jasmonate.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q949U1-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    538
  • Mass (Da)
    61,695
  • Last updated
    2001-12-01 v1
  • Checksum
    4001A1179BBE5ADD
MMSFTTSLPYPFHILLVFILSMASITLLGRILSRPTKTKDRSCQLPPGPPGWPILGNLPELFMTRPRSKYFRLAMKELKTDIACFNFAGIRAITINSDEIAREAFRERDADLADRPQLFIMETIGDNYKSMGISPYGEQFMKMKRVITTEIMSVKTLKMLEAARTIEADNLIAYVHSMYQRSETVDVRELSRVYGYAVTMRMLFGRRHVTKENVFSDDGRLGNAEKHHLEVIFNTLNCLPSFSPADYVERWLRGWNVDGQEKRVTENCNIVRSYNNPIIDERVQLWREEGGKAAVEDWLDTFITLKDQNGKYLVTPDEIKAQCVEFCIAAIDNPANNMEWTLGEMLKNPEILRKALKELDEVVGRDRLVQESDIPNLNYLKACCRETFRIHPSAHYVPSHLARQDTTLGGYFIPKGSHIHVCRPGLGRNPKIWKDPLVYKPERHLQGDGITKEVTLVETEMRFVSFSTGRRGCIGVKVGTIMMVMLLARFLQGFNWKLHQDFGPLSLEEDDASLLMAKPLHLSVEPRLAPNLYPKFRP

Q949U1-2

Sequence caution

The sequence AAD34693.1 differs from that shown. Reason: Erroneous initiation Truncated N-terminus.

Features

Showing features for alternative sequence.

TypeIDPosition(s)Description
Alternative sequenceVSP_030739417-423in isoform 2
Alternative sequenceVSP_030740424-538in isoform 2

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC006341
EMBL· GenBank· DDBJ
AAD34693.1
EMBL· GenBank· DDBJ
Genomic DNA Different initiation
CP002684
EMBL· GenBank· DDBJ
AEE29447.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002684
EMBL· GenBank· DDBJ
AEE29448.1
EMBL· GenBank· DDBJ
Genomic DNA
AY035021
EMBL· GenBank· DDBJ
AAK59526.1
EMBL· GenBank· DDBJ
mRNA
AY050890
EMBL· GenBank· DDBJ
AAK92827.1
EMBL· GenBank· DDBJ
mRNA
AY114074
EMBL· GenBank· DDBJ
AAM45122.1
EMBL· GenBank· DDBJ
mRNA
EF598753
EMBL· GenBank· DDBJ
ABR09166.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598754
EMBL· GenBank· DDBJ
ABR09167.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598755
EMBL· GenBank· DDBJ
ABR09168.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598756
EMBL· GenBank· DDBJ
ABR09169.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598757
EMBL· GenBank· DDBJ
ABR09170.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598758
EMBL· GenBank· DDBJ
ABR09171.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598759
EMBL· GenBank· DDBJ
ABR09172.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598760
EMBL· GenBank· DDBJ
ABR09173.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598761
EMBL· GenBank· DDBJ
ABR09174.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598762
EMBL· GenBank· DDBJ
ABR09175.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598763
EMBL· GenBank· DDBJ
ABR09176.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598764
EMBL· GenBank· DDBJ
ABR09177.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598765
EMBL· GenBank· DDBJ
ABR09178.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598766
EMBL· GenBank· DDBJ
ABR09179.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598767
EMBL· GenBank· DDBJ
ABR09180.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598768
EMBL· GenBank· DDBJ
ABR09181.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598769
EMBL· GenBank· DDBJ
ABR09182.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598770
EMBL· GenBank· DDBJ
ABR09183.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598771
EMBL· GenBank· DDBJ
ABR09184.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598772
EMBL· GenBank· DDBJ
ABR09185.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598773
EMBL· GenBank· DDBJ
ABR09186.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598774
EMBL· GenBank· DDBJ
ABR09187.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598775
EMBL· GenBank· DDBJ
ABR09188.1
EMBL· GenBank· DDBJ
Genomic DNA
EF598776
EMBL· GenBank· DDBJ
ABR09189.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

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