Q949P1 · ABAH1_ARATH
- ProteinAbscisic acid 8'-hydroxylase 1
- GeneCYP707A1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids467 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Involved in the oxidative degradation of abscisic acid. Plays an important role in determining abscisic acid levels in dry seeds and in the control of postgermination growth.
Catalytic activity
- 2-cis-+-abscisate + O2 + reduced [NADPH--hemoprotein reductase] = +-8'-hydroxyabscisate + H+ + H2O + oxidized [NADPH--hemoprotein reductase]
Cofactor
Pathway
Plant hormone degradation; abscisic acid degradation.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Molecular Function | (+)-abscisic acid 8'-hydroxylase activity | |
Molecular Function | heme binding | |
Molecular Function | iron ion binding | |
Biological Process | abscisic acid catabolic process | |
Biological Process | abscisic acid metabolic process | |
Biological Process | sterol metabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameAbscisic acid 8'-hydroxylase 1
- EC number
- Short namesABA 8'-hydroxylase 1
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ949P1
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 5-24 | Helical | ||||
Sequence: ALFLTLFAGSLFLYFLRCLI |
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Plants show a reduced germination.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 38 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000288639 | 1-467 | Abscisic acid 8'-hydroxylase 1 | |||
Sequence: MDISALFLTLFAGSLFLYFLRCLISQRRFGSSKLPLPPGTMGWPYVGETFQLYSQDPNVFFQSKQKRYGSVFKTHVLGCPCVMISSPEAAKFVLVTKSHLFKPTFPASKERMLGKQAIFFHQGDYHAKLRKLVLRAFMPESIRNMVPDIESIAQDSLRSWEGTMINTYQEMKTYTFNVALLSIFGKDEVLYREDLKRCYYILEKGYNSMPVNLPGTLFHKSMKARKELSQILARILSERRQNGSSHNDLLGSFMGDKEELTDEQIADNIIGVIFAARDTTASVMSWILKYLAENPNVLEAVTEEQMAIRKDKEEGESLTWGDTKKMPLTSRVIQETLRVASILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHSADIFSNPGKFDPSRFEVAPKPNTFMPFGNGTHSCPGNELAKLEMSIMIHHLTTKYSWSIVGASDGIQYGPFALPQNGLPIVLARKPEIEV |
Proteomic databases
Expression
Tissue specificity
Mainly expressed in flowers, siliques, roots and stems. Lower expression in rosette leaves and dry seeds. Expressed in vascular tissues of embryo during the seed development.
Induction
By abscisic acid treatment, salt or osmotic stresses, and by dehydration and rehydration. Expression regulated by phytochrome B.
Developmental stage
Expressed predominantly during mid-maturation of seed and down-regulated during late maturation. Up-regulated 12 hours after seed imbibition.
Gene expression databases
Structure
Sequence
- Sequence statusComplete
This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.
Q949P1-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length467
- Mass (Da)53,037
- Last updated2001-12-01 v1
- Checksum2F4230446536D955
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A8MRX5 | A8MRX5_ARATH | CYP707A1 | 484 |
Sequence caution
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB122149 EMBL· GenBank· DDBJ | BAD16629.1 EMBL· GenBank· DDBJ | mRNA | ||
AL021687 EMBL· GenBank· DDBJ | CAA16713.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AL161550 EMBL· GenBank· DDBJ | CAB78925.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002687 EMBL· GenBank· DDBJ | AEE84162.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY050980 EMBL· GenBank· DDBJ | AAK93657.1 EMBL· GenBank· DDBJ | mRNA | ||
AY091446 EMBL· GenBank· DDBJ | AAM14385.1 EMBL· GenBank· DDBJ | mRNA |