Q949P1 · ABAH1_ARATH

Function

function

Involved in the oxidative degradation of abscisic acid. Plays an important role in determining abscisic acid levels in dry seeds and in the control of postgermination growth.

Catalytic activity

Cofactor

heme (UniProtKB | Rhea| CHEBI:30413 )

Pathway

Plant hormone degradation; abscisic acid degradation.

Features

Showing features for binding site.

146750100150200250300350400450
TypeIDPosition(s)Description
Binding site411Fe (UniProtKB | ChEBI) of heme (UniProtKB | ChEBI); axial binding residue

GO annotations

AspectTerm
Cellular Componentmembrane
Molecular Function(+)-abscisic acid 8'-hydroxylase activity
Molecular Functionheme binding
Molecular Functioniron ion binding
Biological Processabscisic acid catabolic process
Biological Processabscisic acid metabolic process
Biological Processsterol metabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Abscisic acid 8'-hydroxylase 1
  • EC number
  • Short names
    ABA 8'-hydroxylase 1
  • Alternative names
    • Cytochrome P450 707A1

Gene names

    • Name
      CYP707A1
    • ORF names
      T18B16.200
    • Ordered locus names
      At4g19230

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q949P1
  • Secondary accessions
    • O65624

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Membrane
; Single-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane5-24Helical

Keywords

Phenotypes & Variants

Disruption phenotype

Plants show a reduced germination.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 38 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00002886391-467Abscisic acid 8'-hydroxylase 1

Proteomic databases

Expression

Tissue specificity

Mainly expressed in flowers, siliques, roots and stems. Lower expression in rosette leaves and dry seeds. Expressed in vascular tissues of embryo during the seed development.

Induction

By abscisic acid treatment, salt or osmotic stresses, and by dehydration and rehydration. Expression regulated by phytochrome B.

Developmental stage

Expressed predominantly during mid-maturation of seed and down-regulated during late maturation. Up-regulated 12 hours after seed imbibition.

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the cytochrome P450 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete

This entry describes 1 isoforms produced by Alternative splicing. A number of isoforms are produced. According to EST sequences.

Q949P1-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    467
  • Mass (Da)
    53,037
  • Last updated
    2001-12-01 v1
  • Checksum
    2F4230446536D955
MDISALFLTLFAGSLFLYFLRCLISQRRFGSSKLPLPPGTMGWPYVGETFQLYSQDPNVFFQSKQKRYGSVFKTHVLGCPCVMISSPEAAKFVLVTKSHLFKPTFPASKERMLGKQAIFFHQGDYHAKLRKLVLRAFMPESIRNMVPDIESIAQDSLRSWEGTMINTYQEMKTYTFNVALLSIFGKDEVLYREDLKRCYYILEKGYNSMPVNLPGTLFHKSMKARKELSQILARILSERRQNGSSHNDLLGSFMGDKEELTDEQIADNIIGVIFAARDTTASVMSWILKYLAENPNVLEAVTEEQMAIRKDKEEGESLTWGDTKKMPLTSRVIQETLRVASILSFTFREAVEDVEYEGYLIPKGWKVLPLFRNIHHSADIFSNPGKFDPSRFEVAPKPNTFMPFGNGTHSCPGNELAKLEMSIMIHHLTTKYSWSIVGASDGIQYGPFALPQNGLPIVLARKPEIEV

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A8MRX5A8MRX5_ARATHCYP707A1484

Sequence caution

The sequence CAA16713.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence CAB78925.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AB122149
EMBL· GenBank· DDBJ
BAD16629.1
EMBL· GenBank· DDBJ
mRNA
AL021687
EMBL· GenBank· DDBJ
CAA16713.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161550
EMBL· GenBank· DDBJ
CAB78925.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE84162.1
EMBL· GenBank· DDBJ
Genomic DNA
AY050980
EMBL· GenBank· DDBJ
AAK93657.1
EMBL· GenBank· DDBJ
mRNA
AY091446
EMBL· GenBank· DDBJ
AAM14385.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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