Q948Z0 · TPSD6_ABIGR
- ProteinCamphene synthase, chloroplastic
- Geneag6
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids618 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Involved in defensive oleoresin formation in conifers in response to insect attack or other injury. Involved in monoterpene (C10) olefins biosynthesis.
Miscellaneous
The conserved 59-Arg-Arg-60 motif may play a role in the isomerization step of the terpenoid cyclization reaction sequence.
Catalytic activity
- (2E)-geranyl diphosphate = (1S,4R)-camphene + diphosphate
Cofactor
Protein has several cofactor binding sites:
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Binds 3 Mg2+ or Mn2+ ions per subunit.
Pathway
Terpene metabolism; oleoresin biosynthesis.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | chloroplast | |
Molecular Function | camphene synthase activity | |
Molecular Function | magnesium ion binding | |
Molecular Function | terpene synthase activity | |
Biological Process | diterpenoid biosynthetic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCamphene synthase, chloroplastic
- EC number
- Alternative names
Gene names
Organism names
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Pinopsida > Pinidae > Conifers I > Pinales > Pinaceae > Abies
Accessions
- Primary accessionQ948Z0
Subcellular Location
PTM/Processing
Features
Showing features for transit peptide, chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transit peptide | 1-51 | Chloroplast | ||||
Sequence: MALLSITPLVSRSCLSSSHEIKALRRTIPTLGICRPGKSVAHSINMCLTSV | ||||||
Chain | PRO_0000033629 | 52-618 | Camphene synthase, chloroplastic | |||
Sequence: ASTDSVQRRVGNYHSNLWDDDFIQSLISTPYGAPDYRERADRLIGEVKDIMFNFKSLEDGGNDLLQRLLLVDDVERLGIDRHFKKEIKTALDYVNSYWNEKGIGCGRESVVTDLNSTALGLRTLRLHGYTVSSDVLNVFKDKNGQFSSTANIQIEGEIRGVLNLFRASLVAFPGEKVMDEAETFSTKYLREALQKIPASSILSLEIRDVLEYGWHTNLPRLEARNYMDVFGQHTKNKNAAEKLLELAKLEFNIFHSLQERELKHVSRWWKDSGSPEMTFCRHRHVEYYALASCIAFEPQHSGFRLGFTKMSHLITVLDDMYDVFGTVDELELFTATIKRWDPSAMECLPEYMKGVYMMVYHTVNEMARVAEKAQGRDTLNYARQAWEACFDSYMQEAKWIATGYLPTFEEYLENGKVSSAHRPCALQPILTLDIPFPDHILKEVDFPSKLNDLICIILRLRGDTRCYKADRARGEEASSISCYMKDNPGLTEEDALNHINFMIRDAIRELNWELLKPDNSVPITSKKHAFDISRVWHHGYRYRDGYSFANVETKSLVMRTVIEPVPL |
Structure
Family & Domains
Features
Showing features for motif.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Motif | 369-373 | DDXXD motif | ||||
Sequence: DDMYD |
Domain
The Asp-Asp-Xaa-Xaa-Asp/Glu (DDXXD/E) motif is important for the catalytic activity, presumably through binding to Mg2+.
Sequence similarities
Belongs to the terpene synthase family. Tpsd subfamily.
Keywords
- Domain
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length618
- Mass (Da)70,750
- Last updated2001-12-01 v1
- ChecksumB07B5185CE5C4CE1
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
U87910 EMBL· GenBank· DDBJ | AAB70707.1 EMBL· GenBank· DDBJ | mRNA |