Q940A2 · P2C31_ARATH
- ProteinProtein kinase and PP2C-like domain-containing protein
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids658 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score4/5
Function
Catalytic activity
- ATP + L-seryl-[protein] = ADP + H+ + O-phospho-L-seryl-[protein]
Cofactor
Mn2+ (UniProtKB | Rhea| CHEBI:29035 )
Note: Binds 2 magnesium or manganese ions per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 36-44 | ATP (UniProtKB | ChEBI) | ||||
Sequence: IAKGSESVV | ||||||
Binding site | 57 | ATP (UniProtKB | ChEBI) | ||||
Sequence: K | ||||||
Active site | 149 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 428 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 428 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 429 | Mn2+ 1 (UniProtKB | ChEBI) | ||||
Sequence: G | ||||||
Binding site | 599 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 639 | Mn2+ 2 (UniProtKB | ChEBI) | ||||
Sequence: D |
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | myosin phosphatase activity | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Biological Process | L-ascorbic acid metabolic process |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameProtein kinase and PP2C-like domain-containing protein
Including 2 domains:
- Recommended nameProbable serine/threonine protein kinase At2g40860
- EC number
- Recommended nameProbable protein phosphatase 2C 31
- EC number
- Short namesAtPP2C31
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ940A2
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000367959 | 1-658 | Protein kinase and PP2C-like domain-containing protein | |||
Sequence: MVMEIVKPNTCIRGCCTSESIPLHLPSSSFTLLSPIAKGSESVVYEAILDGRRVAAKKPILSTSDDLDKFHRNLQLSCNLNHPGVAKLLAAHAKPPNYMFFFDFYESGTLAEKLHVEEWSPSIDQVLLITLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVNLQNWRSSGKPTGGFHKKNMVGTLIYMAPEILRKDMYTEKADIYSFGILINELLTGVVPYTDRRAEAQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPKSLLSLIQNCWESDPSKRPSSDNVVLELESIWEQVRGKQQGHLLEKTSNSQSDTDGADIIKNSGDYRDTVNWFSQGECLSKKSSVSTVFDVKLWSSSTDEPSRYVPVISCGSFATCGRRESMEDTHFIIPHMCNEESIHLFAIFDGHRGAAAAEFSAQVLPGLVQSLCSTSAGEALSQAFVRTDLAFRQELDSHRQSKRVSQKDWHPGCTAIASLLVENKLFVANVGDSRAILCRAGHPFALSKAHLATCIDERNRVIGEGGRIEWLVDTWRVAPAGLQVTRSIGDDDLKPAVTAEPEISETILSADDEFLVMASDGLWDVMNDEEVIGIIRDTVKEPSMCSKRLATEAAARGSGDNITVIVVFLRPVSTAERIY |
Proteomic databases
PTM databases
Expression
Gene expression databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 30-314 | Protein kinase | ||||
Sequence: FTLLSPIAKGSESVVYEAILDGRRVAAKKPILSTSDDLDKFHRNLQLSCNLNHPGVAKLLAAHAKPPNYMFFFDFYESGTLAEKLHVEEWSPSIDQVLLITLHLAKALQYLHNNGIVHRDVKPANVLLDEKFFPYLADFGLAEYKKNLREVNLQNWRSSGKPTGGFHKKNMVGTLIYMAPEILRKDMYTEKADIYSFGILINELLTGVVPYTDRRAEAQAHTVLEMNYTEQQLTVAIVSSGLRPALAEIGLHLPKSLLSLIQNCWESDPSKRPSSDNVVLELESI | ||||||
Domain | 392-648 | PPM-type phosphatase | ||||
Sequence: SCGSFATCGRRESMEDTHFIIPHMCNEESIHLFAIFDGHRGAAAAEFSAQVLPGLVQSLCSTSAGEALSQAFVRTDLAFRQELDSHRQSKRVSQKDWHPGCTAIASLLVENKLFVANVGDSRAILCRAGHPFALSKAHLATCIDERNRVIGEGGRIEWLVDTWRVAPAGLQVTRSIGDDDLKPAVTAEPEISETILSADDEFLVMASDGLWDVMNDEEVIGIIRDTVKEPSMCSKRLATEAAARGSGDNITVIVVFL |
Sequence similarities
In the N-terminal section; belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
In the C-terminal section; belongs to the PP2C family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length658
- Mass (Da)72,853
- Last updated2001-12-01 v1
- Checksum66041EE6EAEFEE14
Computationally mapped potential isoform sequences
There are 3 potential isoforms mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8B331 | A0A1P8B331_ARATH | At2g40860 | 560 | ||
A0A1P8B342 | A0A1P8B342_ARATH | At2g40860 | 611 | ||
A0A1P8B344 | A0A1P8B344_ARATH | At2g40860 | 636 |
Sequence caution
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AC002409 EMBL· GenBank· DDBJ | AAB86446.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
AC002409 EMBL· GenBank· DDBJ | AAB86447.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002685 EMBL· GenBank· DDBJ | AEC09891.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY056151 EMBL· GenBank· DDBJ | AAL07230.1 EMBL· GenBank· DDBJ | mRNA | ||
AY133729 EMBL· GenBank· DDBJ | AAM91663.1 EMBL· GenBank· DDBJ | mRNA |