Q93WK5 · APRR7_ARATH
- ProteinTwo-component response regulator-like APRR7
- GeneAPRR7
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids727 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Transcriptional repressor of CCA1 and LHY, and positive regulator of LWD1 and LWD2 expression. Represses the expression of other clock proteins and master regulators of plant growth, development and response to abiotic stress. Involved in the positive and negative feedback loops of the circadian clock. Controls photoperiodic flowering response and temperature compensation. Expression of several members of the ARR-like family is controlled by circadian rhythm. APRR9, APRR7, and APRR5 coordinately act on the upstream region of the target genes to repress their expression from noon until midnight. The particular coordinated sequential expression of APRR9, APRR7, APRR5, APRR3 and APPR1 result to circadian waves that may be at the basis of the endogenous circadian clock.
Miscellaneous
Regulated at the level of mRNA maturation and alternative splicing by SKIP (PubMed:22942380).
The expression of APRR9, APRR7, and APRR5 requires the presence of LWD1 and/or LWD2, indicating the existence of a positive feedback loop within the circadian clock (PubMed:21357491).
The expression of APRR9, APRR7, and APRR5 requires the presence of LWD1 and/or LWD2, indicating the existence of a positive feedback loop within the circadian clock (PubMed:21357491).
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | mitochondrion | |
Cellular Component | nucleus | |
Molecular Function | DNA binding | |
Biological Process | circadian rhythm | |
Biological Process | cytokinin-activated signaling pathway | |
Biological Process | negative regulation of DNA-templated transcription | |
Biological Process | phosphorelay signal transduction system | |
Biological Process | red or far-red light signaling pathway | |
Biological Process | regulation of DNA-templated transcription |
Keywords
- Biological process
Names & Taxonomy
Protein names
- Recommended nameTwo-component response regulator-like APRR7
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ93WK5
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
Insensitive to the effect of sucrose on the circadian period.
Variants
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The viewer provides 52 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000081439 | 1-727 | Two-component response regulator-like APRR7 | |||
Sequence: MNANEEGEGSRYPITDRKTGETKFDRVESRTEKHSEEEKTNGITMDVRNGSSGGLQIPLSQQTAATVCWERFLHVRTIRVLLVENDDCTRYIVTALLRNCSYEVVEASNGIQAWKVLEDLNNHIDIVLTEVIMPYLSGIGLLCKILNHKSRRNIPVIMMSSHDSMGLVFKCLSKGAVDFLVKPIRKNELKILWQHVWRRCQSSSGSGSESGTHQTQKSVKSKSIKKSDQDSGSSDENENGSIGLNASDGSSDGSGAQSSWTKKAVDVDDSPRAVSLWDRVDSTCAQVVHSNPEFPSNQLVAPPAEKETQEHDDKFEDVTMGRDLEISIRRNCDLALEPKDEPLSKTTGIMRQDNSFEKSSSKWKMKVGKGPLDLSSESPSSKQMHEDGGSSFKAMSSHLQDNREPEAPNTHLKTLDTNEASVKISEELMHVEHSSKRHRGTKDDGTLVRDDRNVLRRSEGSAFSRYNPASNANKISGGNLGSTSLQDNNSQDLIKKTEAAYDCHSNMNESLPHNHRSHVGSNNFDMSSTTENNAFTKPGAPKVSSAGSSSVKHSSFQPLPCDHHNNHASYNLVHVAERKKLPPQCGSSNVYNETIEGNNNTVNYSVNGSVSGSGHGSNGPYGSSNGMNAGGMNMGSDNGAGKNGNGDGSGSGSGSGSGNLADENKISQREAALTKFRQKRKERCFRKKVRYQSRKKLAEQRPRVRGQFVRKTAAATDDNDIKNIEDS |
Post-translational modification
Phosphorylated. Phosphorylation varies throughout the diurnal cycle.
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Induction
Up-regulated by heat-shock and light at dawn, and down-regulated by the sugars produced by photosynthesis.
Gene expression databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | Intact | |
---|---|---|---|---|---|
BINARY | Q93WK5 | PYL8 Q9FGM1 | 3 | EBI-25528701, EBI-2429535 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-47 | Disordered | ||||
Sequence: MNANEEGEGSRYPITDRKTGETKFDRVESRTEKHSEEEKTNGITMDV | ||||||
Compositional bias | 10-43 | Basic and acidic residues | ||||
Sequence: SRYPITDRKTGETKFDRVESRTEKHSEEEKTNGI | ||||||
Domain | 79-197 | Response regulatory | ||||
Sequence: RVLLVENDDCTRYIVTALLRNCSYEVVEASNGIQAWKVLEDLNNHIDIVLTEVIMPYLSGIGLLCKILNHKSRRNIPVIMMSSHDSMGLVFKCLSKGAVDFLVKPIRKNELKILWQHVW | ||||||
Compositional bias | 203-218 | Polar residues | ||||
Sequence: SSGSGSESGTHQTQKS | ||||||
Region | 203-265 | Disordered | ||||
Sequence: SSGSGSESGTHQTQKSVKSKSIKKSDQDSGSSDENENGSIGLNASDGSSDGSGAQSSWTKKAV | ||||||
Compositional bias | 234-264 | Polar residues | ||||
Sequence: SDENENGSIGLNASDGSSDGSGAQSSWTKKA | ||||||
Region | 291-312 | Disordered | ||||
Sequence: NPEFPSNQLVAPPAEKETQEHD | ||||||
Region | 339-416 | Disordered | ||||
Sequence: KDEPLSKTTGIMRQDNSFEKSSSKWKMKVGKGPLDLSSESPSSKQMHEDGGSSFKAMSSHLQDNREPEAPNTHLKTLD | ||||||
Region | 464-487 | Disordered | ||||
Sequence: SRYNPASNANKISGGNLGSTSLQD | ||||||
Region | 509-560 | Disordered | ||||
Sequence: ESLPHNHRSHVGSNNFDMSSTTENNAFTKPGAPKVSSAGSSSVKHSSFQPLP | ||||||
Compositional bias | 606-664 | Polar residues | ||||
Sequence: VNGSVSGSGHGSNGPYGSSNGMNAGGMNMGSDNGAGKNGNGDGSGSGSGSGSGNLADEN | ||||||
Region | 606-670 | Disordered | ||||
Sequence: VNGSVSGSGHGSNGPYGSSNGMNAGGMNMGSDNGAGKNGNGDGSGSGSGSGSGNLADENKISQRE | ||||||
Domain | 669-711 | CCT | ||||
Sequence: REAALTKFRQKRKERCFRKKVRYQSRKKLAEQRPRVRGQFVRK |
Sequence similarities
Belongs to the ARR-like family.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length727
- Mass (Da)79,663
- Last updated2001-12-01 v1
- Checksum13057E6AE6E50C00
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8BCB0 | A0A1P8BCB0_ARATH | PRR7 | 583 |
Sequence caution
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 10-43 | Basic and acidic residues | ||||
Sequence: SRYPITDRKTGETKFDRVESRTEKHSEEEKTNGI | ||||||
Compositional bias | 203-218 | Polar residues | ||||
Sequence: SSGSGSESGTHQTQKS | ||||||
Compositional bias | 234-264 | Polar residues | ||||
Sequence: SDENENGSIGLNASDGSSDGSGAQSSWTKKA | ||||||
Compositional bias | 606-664 | Polar residues | ||||
Sequence: VNGSVSGSGHGSNGPYGSSNGMNAGGMNMGSDNGAGKNGNGDGSGSGSGSGSGNLADEN |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB046954 EMBL· GenBank· DDBJ | BAB13742.1 EMBL· GenBank· DDBJ | mRNA | ||
AL162973 EMBL· GenBank· DDBJ | CAB86035.1 EMBL· GenBank· DDBJ | Genomic DNA | Sequence problems. | |
CP002688 EMBL· GenBank· DDBJ | AED90520.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY039943 EMBL· GenBank· DDBJ | AAK64047.1 EMBL· GenBank· DDBJ | mRNA | ||
AY142560 EMBL· GenBank· DDBJ | AAN13129.1 EMBL· GenBank· DDBJ | mRNA |