Q93VK8 · GLV1_ARATH

Function

function

GLV1p

Signaling peptide (root growth factor) that regulates the pattern of root growth and lateral root development by modulating the length and the number of cortical cells in the root apical meristem (RAM), and the anticlinal asymmetric cell divisions in lateral root initiation cells (PubMed:22307643, PubMed:23370719).
Also involved in the regulation of hypocotyl bending and root gravitropism in a PIN2-traffic dependent manner, thus influencing the formation of auxin gradients (PubMed:22421050).
Maintains the postembryonic root stem cell niche (PubMed:20798316).

Miscellaneous

'Golven' means irregular waves in Dutch.

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentendoplasmic reticulum
Cellular Componentextracellular space
Molecular Functiongrowth factor activity
Molecular Functionhormone activity
Biological Processcell differentiation
Biological Processlateral root development
Biological Processpositive gravitropism
Biological Processpositive regulation of cell population proliferation
Biological Processregulation of asymmetric cell division
Biological Processregulation of auxin polar transport
Biological Processregulation of lateral root development
Biological Processregulation of protein localization
Biological Processregulation of root development
Biological Processregulation of root meristem growth
Biological Processregulation of root morphogenesis
Biological Processresponse to auxin
Biological Processroot system development

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Protein GOLVEN 1
  • Alternative names
    • CLAVATA3/ESR (CLE)-related protein CLEL6
      (CLE-Like protein 6
      )
    • Root meristem growth factor 6
      (AtRGF6
      )
  • Cleaved into 1 chains

Gene names

    • Name
      GLV1
    • Synonyms
      CLEL6
      , RGF6
    • ORF names
      FCAALL
    • Ordered locus names
      At4g16515

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q93VK8

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Endoplasmic reticulum
Note: The precursor is detected in the endoplasmic reticulum probably during its processing.

GLV1p

Secreted

Keywords

Phenotypes & Variants

Disruption phenotype

Reduced hypocotyl bending and dose-dependent altered root gravitropism associated with an altered PIN2 traffic that impairs the formation of auxin gradients, thus leading to an irregular waves root shape.

Variants

We now provide the "Disease & Variants" viewer in its own tab.

The viewer provides 5 variants from UniProt as well as other sources including ClinVar and dbSNP.

Go to variant viewer

PTM/Processing

Features

Showing features for signal, propeptide, peptide, modified residue.

TypeIDPosition(s)Description
Signal1-29
PropeptidePRO_000040144930-70
PeptidePRO_000040145071-83GLV1p
Modified residue72Sulfotyrosine
Modified residue80Hydroxyproline
PropeptidePRO_000040145184-86

Keywords

Proteomic databases

Expression

Tissue specificity

Expressed in stems, hypocotyls, cotyledons, leaves, flowers, shoot apex, siliques, stamens and petals.

Induction

Rapidly induced by auxin.

Developmental stage

Absent from the primary root (PubMed:23370719).
Expressed irregularly throughout the cotyledon and accumulates at the base of the organ (PubMed:23370719).
In leaves, present at a high level in the basal part, close to the main veins, irregularly in the lamina joining these veins, and in separate segments of the leaf margin (PubMed:23370719).
Observed in the stem, the rachis of the inflorescence, and the lower portion of the flower pedicel, especially at its upper side (PubMed:23370719).
In flowers, detected throughout its development at the base of the sepals, in the petals, the filament of the stamens and the gynoecium, and later in siliques (PubMed:23370719).
During seedling gravitropic response, restricted to the epidermis and cortex and enhanced at the lower side of the reoriented hypocotyl (PubMed:22421050).

Gene expression databases

Interaction

Subunit

GLV1p

Binds to LRR receptor-like serine/threonine-protein kinases to trigger their dimerization with SERK proteins and subsequent signaling.

Protein-protein interaction databases

Family & Domains

Sequence similarities

Belongs to the RGF family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    86
  • Mass (Da)
    9,541
  • Last updated
    2001-12-01 v1
  • Checksum
    A37697E69DE9B7F3
MSCSLRSGLVIVFCFILLLLSSNVGCASAARRLRSHKHHHHKVASLDVFNGGERRRALGGVETGEEVVVMDYPQPHRKPPIHNEKS

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A1P8B471A0A1P8B471_ARATHRGF6147

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL161544
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002687
EMBL· GenBank· DDBJ
AEE83763.1
EMBL· GenBank· DDBJ
Genomic DNA
AF380632
EMBL· GenBank· DDBJ
AAK55713.1
EMBL· GenBank· DDBJ
mRNA
AY054128
EMBL· GenBank· DDBJ
AAL06789.1
EMBL· GenBank· DDBJ
mRNA
AY088419
EMBL· GenBank· DDBJ
AAM65956.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. Our staff consists of biologists and biochemists that are not trained to give medical advice.
We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.
FeedbackHelp