Q93VK8 · GLV1_ARATH
- ProteinProtein GOLVEN 1
- GeneGLV1
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
GLV1p
Signaling peptide (root growth factor) that regulates the pattern of root growth and lateral root development by modulating the length and the number of cortical cells in the root apical meristem (RAM), and the anticlinal asymmetric cell divisions in lateral root initiation cells (PubMed:22307643, PubMed:23370719).
Also involved in the regulation of hypocotyl bending and root gravitropism in a PIN2-traffic dependent manner, thus influencing the formation of auxin gradients (PubMed:22421050).
Maintains the postembryonic root stem cell niche (PubMed:20798316).
Also involved in the regulation of hypocotyl bending and root gravitropism in a PIN2-traffic dependent manner, thus influencing the formation of auxin gradients (PubMed:22421050).
Maintains the postembryonic root stem cell niche (PubMed:20798316).
Miscellaneous
'Golven' means irregular waves in Dutch.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | endoplasmic reticulum | |
Cellular Component | extracellular space | |
Molecular Function | growth factor activity | |
Molecular Function | hormone activity | |
Biological Process | cell differentiation | |
Biological Process | lateral root development | |
Biological Process | positive gravitropism | |
Biological Process | positive regulation of cell population proliferation | |
Biological Process | regulation of asymmetric cell division | |
Biological Process | regulation of auxin polar transport | |
Biological Process | regulation of lateral root development | |
Biological Process | regulation of protein localization | |
Biological Process | regulation of root development | |
Biological Process | regulation of root meristem growth | |
Biological Process | regulation of root morphogenesis | |
Biological Process | response to auxin | |
Biological Process | root system development |
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameProtein GOLVEN 1
- Alternative names
- Cleaved into 1 chains
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ93VK8
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Note: The precursor is detected in the endoplasmic reticulum probably during its processing.
GLV1p
Keywords
- Cellular component
Phenotypes & Variants
Disruption phenotype
Reduced hypocotyl bending and dose-dependent altered root gravitropism associated with an altered PIN2 traffic that impairs the formation of auxin gradients, thus leading to an irregular waves root shape.
Variants
We now provide the "Disease & Variants" viewer in its own tab.
The viewer provides 5 variants from UniProt as well as other sources including ClinVar and dbSNP.
PTM/Processing
Features
Showing features for signal, propeptide, peptide, modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-29 | |||||
Sequence: MSCSLRSGLVIVFCFILLLLSSNVGCASA | ||||||
Propeptide | PRO_0000401449 | 30-70 | ||||
Sequence: ARRLRSHKHHHHKVASLDVFNGGERRRALGGVETGEEVVVM | ||||||
Peptide | PRO_0000401450 | 71-83 | GLV1p | |||
Sequence: DYPQPHRKPPIHN | ||||||
Modified residue | 72 | Sulfotyrosine | ||||
Sequence: Y | ||||||
Modified residue | 80 | Hydroxyproline | ||||
Sequence: P | ||||||
Propeptide | PRO_0000401451 | 84-86 | ||||
Sequence: EKS |
Keywords
- PTM
Proteomic databases
Expression
Tissue specificity
Expressed in stems, hypocotyls, cotyledons, leaves, flowers, shoot apex, siliques, stamens and petals.
Induction
Rapidly induced by auxin.
Developmental stage
Absent from the primary root (PubMed:23370719).
Expressed irregularly throughout the cotyledon and accumulates at the base of the organ (PubMed:23370719).
In leaves, present at a high level in the basal part, close to the main veins, irregularly in the lamina joining these veins, and in separate segments of the leaf margin (PubMed:23370719).
Observed in the stem, the rachis of the inflorescence, and the lower portion of the flower pedicel, especially at its upper side (PubMed:23370719).
In flowers, detected throughout its development at the base of the sepals, in the petals, the filament of the stamens and the gynoecium, and later in siliques (PubMed:23370719).
During seedling gravitropic response, restricted to the epidermis and cortex and enhanced at the lower side of the reoriented hypocotyl (PubMed:22421050).
Expressed irregularly throughout the cotyledon and accumulates at the base of the organ (PubMed:23370719).
In leaves, present at a high level in the basal part, close to the main veins, irregularly in the lamina joining these veins, and in separate segments of the leaf margin (PubMed:23370719).
Observed in the stem, the rachis of the inflorescence, and the lower portion of the flower pedicel, especially at its upper side (PubMed:23370719).
In flowers, detected throughout its development at the base of the sepals, in the petals, the filament of the stamens and the gynoecium, and later in siliques (PubMed:23370719).
During seedling gravitropic response, restricted to the epidermis and cortex and enhanced at the lower side of the reoriented hypocotyl (PubMed:22421050).
Gene expression databases
Structure
Family & Domains
Sequence similarities
Belongs to the RGF family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
- Length86
- Mass (Da)9,541
- Last updated2001-12-01 v1
- ChecksumA37697E69DE9B7F3
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1P8B471 | A0A1P8B471_ARATH | RGF6 | 147 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL161544 EMBL· GenBank· DDBJ | - | Genomic DNA | No translation available. | |
CP002687 EMBL· GenBank· DDBJ | AEE83763.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AF380632 EMBL· GenBank· DDBJ | AAK55713.1 EMBL· GenBank· DDBJ | mRNA | ||
AY054128 EMBL· GenBank· DDBJ | AAL06789.1 EMBL· GenBank· DDBJ | mRNA | ||
AY088419 EMBL· GenBank· DDBJ | AAM65956.1 EMBL· GenBank· DDBJ | mRNA |