Q92PB7 · Q92PB7_RHIME
- ProteinPhosphoglycolate phosphatase
- Genegph1
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids227 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Specifically catalyzes the dephosphorylation of 2-phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress.
Catalytic activity
- 2-phosphoglycolate + H2O = glycolate + phosphate
Cofactor
Pathway
Organic acid metabolism; glycolate biosynthesis; glycolate from 2-phosphoglycolate: step 1/1.
Features
Showing features for active site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Active site | 9 | Nucleophile | |||
Binding site | 9 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 11 | Mg2+ (UniProtKB | ChEBI) | |||
Binding site | 171 | Mg2+ (UniProtKB | ChEBI) | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Molecular Function | metal ion binding | |
Molecular Function | phosphoglycolate phosphatase activity | |
Biological Process | carbohydrate metabolic process | |
Biological Process | dephosphorylation | |
Biological Process | DNA repair | |
Biological Process | glycolate biosynthetic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePhosphoglycolate phosphatase
- EC number
- Short namesPGP ; PGPase
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Alphaproteobacteria > Hyphomicrobiales > Rhizobiaceae > Sinorhizobium/Ensifer group > Sinorhizobium
Accessions
- Primary accessionQ92PB7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Structure
Sequence
- Sequence statusComplete
- Length227
- Mass (Da)24,483
- Last updated2001-12-01 v1
- MD5 Checksum6DACBE2FF3C799B8F6E1AFF69950E122
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL591688 EMBL· GenBank· DDBJ | CAC46436.1 EMBL· GenBank· DDBJ | Genomic DNA |