Refined chromosomal localization of the mismatch repair and hereditary nonpolyposis colorectal cancer genes hMSH2 and hMSH6.Schmutte C., Marinescu R.C., Copeland N.G., Jenkins N.A., Overhauser J., Fishel R.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCCancer Res 58:5023-5026 (1998)Mapped to17
Cloning, expression and genetic mapping of the mouse SH3 domain protein, SH3D2B.Torrey T., Kim W., Morse H.C., Kozak C.A.CategorySequencesSourceMGI: 1353449PubMedEurope PMCMamm Genome 9:74-75 (1998)Mapped to29
Deficient cytokine signaling in mouse embryo fibroblasts with a targeted deletion in the PKR gene: role of IRF-1 and NF-kappaB.Kumar A., Yang Y.L., Flati V., Der S., Kadereit S., Deb A., Haque J., Reis L., Weissmann C., Williams B.R.View abstractCategoryFunctionSourceMGI: 1353449PubMedEurope PMCEMBO J 16:406-416 (1997)Mapped to3
Isolation of the interferon-inducible RNA-dependent protein kinase Pkr promoter and identification of a novel DNA element within the 5'-flanking region of human and mouse Pkr genes.Kuhen K.L., Samuel C.E.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCVirology 227:119-130 (1997)Mapped to3
Mechanism of interferon action sequence of the human interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones.Kuhen K.L., Shen X., Samuel C.E.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCGene 178:191-193 (1996)Cited in1Mapped to3
Structural organization of the human gene (PKR) encoding an interferon- inducible RNA-dependent protein kinase (PKR) and differences from its mouse homolog.Kuhen K.L., Shen X., Carlisle E.R., Richardson A.L., Weier H.-U.G., Tanaka H., Samuel C.E.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCGenomics 36:197-201 (1996)Cited in1Mapped to3
Double-stranded RNA-dependent protein kinase mediates c-Myc suppression induced by type I interferons.Raveh T., Hovanessian A.G., Meurs E.F., Sonenberg N., Kimchi A.View abstractCategoryFunctionSourceMGI: 1353449PubMedEurope PMCJ Biol Chem 271:25479-25484 (1996)Mapped to3
The gene encoding LERK-7 (EPLG7, Epl7), a ligand for the Eph-related receptor tyrosine kinases, maps to human chromosome 5 at band q21 and to mouse chromosome 17.Cerretti D.P., Copeland N.G., Gilbert D.J., Jenkins N.A., Kuefer M.U., Valentine V., Shapiro D.N., Cui X., Morris S.W.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCGenomics 35:376-379 (1996)Mapped to19
Cloning and characterization of mouse CCAAT binding factor.Hoeppner M.A., Gilbert D.J., Copeland N.G., Jenkins N.A., Linzer D.I.H., Wu B.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCNucleic Acids Res. 24:1091-1098 (1996)Cited in1Mapped to12
Mapping of the flaky skin (fsn) mutation on distal mouse chromosome 17.Pelsue S.C., Schweitzer P.A., Beamer W.G., Shultz L.D.CategoriesFunction, SequencesSourceMGI: 1353449PubMedEurope PMCMamm Genome 6:758-758 (1995)Mapped to11
Deficient signaling in mice devoid of double-stranded RNA-dependent protein kinase.Yang Y.L., Reis L.F., Pavlovic J., Aguzzi A., Schafer R., Kumar A., Williams B.R., Aguet M., Weissmann C.View abstractCategoriesFunction, Phenotypes & VariantsSourceMGI: 1353449PubMedEurope PMCEMBO J 14:6095-6106 (1995)Mapped to3
The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.Fishel R., Lescoe M., Rao M., Copeland N.G., Jenkins N.A., Garber J., Kane M.F., Kolodner R.D.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCCell 75:1027-1038 (1993)Cited in1Mapped to14
The eIF-2 alpha protein kinases, regulators of translation in eukaryotes from yeasts to humans.Samuel C.E.CategoryFunctionSourceMGI: 1353449PubMedEurope PMCJ Biol Chem 268:7603-7606 (1993)Mapped to3
Mechanism of interferon action: structure of the mouse PKR gene encoding the interferon-inducible RNA-dependent protein kinase.Tanaka H., Samuel C.E.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCProc. Natl. Acad. Sci. U.S.A. 91:7995-7999 (1994)Cited in1Mapped to2
Localization of the murine homolog of the anaplastic lymphoma kinase (AlK) gene on mouse chromosome 17.Mathew P., Morris S.W., Kane J.R., Shurtleff S.A., Pasquini M., Jenkins N.A., Gilbert D.J., Copeland N.G.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCCytogenet Cell Genet 70:143-144 (1995)Mapped to9
Homeobox genes and connective tissue patterning.Oliver G., Wehr R., Jenkins N.A., Copeland N.G., Cheyette B.N.R., Hartenstein V., Zipursky S.L., Gruss P.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCDevelopment 121:693-705 (1995)Cited in2Mapped to32
Regulation of protein synthesis by heme-regulated eIF-2 alpha kinase.Chen J.J., London I.M.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCTrends Biochem Sci 20:105-108 (1995)Mapped to3
The mouse antiphosphotyrosine immunoreactive kinase, TIK, is indistinguishable from the double-stranded RNA-dependent, interferon- induced protein kinase, PKR.Baier L.J., Shors T., Shors S.T., Jacobs B.L.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCNucleic Acids Res 21:4830-4835 (1993)Mapped to3
Chromosomal assignment of the interferon-inducible double-stranded RNA- dependent protein kinase (PRKR) to human chromosome 2p21-p22 and mouse chromosome 17 E2.Barber G.N., Edelhoff S., Katze M.G., Disteche C.M.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCGenomics 16:765-767 (1993)Mapped to3
PKR: a new name and new roles.Proud C.G.View abstractCategoryFunctionSourceMGI: 1353449PubMedEurope PMCTrends Biochem Sci 20:241-246 (1995)Mapped to14
Sequence of the murine interferon-inducible RNA-dependent protein kinase (PKR) deduced from genomic clones.Tanaka H., Samuel C.E.View abstractCategorySequencesSourceMGI: 1353449PubMedEurope PMCGene 153:283-284 (1995)Cited in1Mapped to2
Interleukin 3 stimulates protein synthesis by regulating double-stranded RNA-dependent protein kinase.Ito T., Jagus R., May W.S.View abstractCategoryPTM / ProcessingSourceMGI: 1353449PubMedEurope PMCProc Natl Acad Sci U S A 91:7455-7459 (1994)Mapped to19
PKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy.Yoshida T., Latt K.Z., Rosenberg A.Z., Santo B.A., Myakala K., Ishimoto Y., Zhao Y., Shrivastav S., Jones B.A.[...], Kopp J.B.View abstractAnnotationPKR activation-induced mitochondrial dysfunction in HIV-transgenic mice with nephropathy.SourceGeneRif: 19106PubMedEurope PMCElife 12:RP91260-RP91260 (2024)Mapped to4
Aberrant RNA sensing in regulatory T cells causes systemic autoimmunity.Luca D., Lee S., Hirota K., Okabe Y., Uehori J., Izawa K., Lanz A.L., Schutte V., Sivri B.[...], Kato H.View abstractSourceMGI: 1353449PubMedEurope PMCSci Adv 10:eadk0820-eadk0820 (2024)Mapped to32
ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.Hu S.B., Heraud-Farlow J., Sun T., Liang Z., Goradia A., Taylor S., Walkley C.R., Li J.B.View abstractAnnotationADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation.CategoryFunctionSourceGeneRif: 19106, MGI: 1353449PubMedEurope PMCMol Cell 83:3869-3884.e7 (2023)Mapped to20