Q91XX6 · Q91XX6_MOUSE

  • Protein
    Protocadherin gamma B4
  • Gene
    Pcdhgb4
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    2/5

Function

function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Features

Showing features for binding site.

1912100200300400500600700800900
TypeIDPosition(s)Description
Binding site39Ca2+ 2 (UniProtKB | ChEBI)
Binding site40Ca2+ 1 (UniProtKB | ChEBI)
Binding site91Ca2+ 1 (UniProtKB | ChEBI)
Binding site93Ca2+ 1 (UniProtKB | ChEBI)
Binding site125Ca2+ 2 (UniProtKB | ChEBI)
Binding site126Ca2+ 2 (UniProtKB | ChEBI)
Binding site127Ca2+ 3 (UniProtKB | ChEBI)
Binding site128Ca2+ 2 (UniProtKB | ChEBI)
Binding site129Ca2+ 3 (UniProtKB | ChEBI)
Binding site144Ca2+ 5 (UniProtKB | ChEBI)
Binding site159Ca2+ 3 (UniProtKB | ChEBI)
Binding site161Ca2+ 2 (UniProtKB | ChEBI)
Binding site165Ca2+ 3 (UniProtKB | ChEBI)
Binding site201Ca2+ 4 (UniProtKB | ChEBI)
Binding site203Ca2+ 5 (UniProtKB | ChEBI)
Binding site216Ca2+ 3 (UniProtKB | ChEBI)
Binding site234Ca2+ 5 (UniProtKB | ChEBI)
Binding site235Ca2+ 5 (UniProtKB | ChEBI)
Binding site236Ca2+ 6 (UniProtKB | ChEBI)
Binding site237Ca2+ 4 (UniProtKB | ChEBI)
Binding site238Ca2+ 6 (UniProtKB | ChEBI)
Binding site253Ca2+ 7 (UniProtKB | ChEBI)
Binding site268Ca2+ 6 (UniProtKB | ChEBI)
Binding site270Ca2+ 6 (UniProtKB | ChEBI)
Binding site274Ca2+ 6 (UniProtKB | ChEBI)
Binding site306Ca2+ 7 (UniProtKB | ChEBI)
Binding site308Ca2+ 8 (UniProtKB | ChEBI)
Binding site321Ca2+ 6 (UniProtKB | ChEBI)
Binding site337Ca2+ 8 (UniProtKB | ChEBI)
Binding site339Ca2+ 9 (UniProtKB | ChEBI)
Binding site340Ca2+ 7 (UniProtKB | ChEBI)
Binding site341Ca2+ 9 (UniProtKB | ChEBI)
Binding site356Ca2+ 10 (UniProtKB | ChEBI)
Binding site371Ca2+ 9 (UniProtKB | ChEBI)
Binding site373Ca2+ 9 (UniProtKB | ChEBI)
Binding site377Ca2+ 9 (UniProtKB | ChEBI)
Binding site409Ca2+ 10 (UniProtKB | ChEBI)
Binding site411Ca2+ 11 (UniProtKB | ChEBI)
Binding site424Ca2+ 9 (UniProtKB | ChEBI)
Binding site442Ca2+ 11 (UniProtKB | ChEBI)
Binding site444Ca2+ 12 (UniProtKB | ChEBI)
Binding site445Ca2+ 10 (UniProtKB | ChEBI)
Binding site446Ca2+ 13 (UniProtKB | ChEBI)
Binding site461Ca2+ 14 (UniProtKB | ChEBI)
Binding site476Ca2+ 13 (UniProtKB | ChEBI)
Binding site478Ca2+ 13 (UniProtKB | ChEBI)
Binding site482Ca2+ 13 (UniProtKB | ChEBI)
Binding site519Ca2+ 14 (UniProtKB | ChEBI)
Binding site521Ca2+ 14 (UniProtKB | ChEBI)
Binding site534Ca2+ 13 (UniProtKB | ChEBI)
Binding site552Ca2+ 15 (UniProtKB | ChEBI)
Binding site553Ca2+ 15 (UniProtKB | ChEBI)
Binding site554Ca2+ 16 (UniProtKB | ChEBI)
Binding site555Ca2+ 15 (UniProtKB | ChEBI)
Binding site556Ca2+ 16 (UniProtKB | ChEBI)
Binding site593Ca2+ 16 (UniProtKB | ChEBI)
Binding site595Ca2+ 16 (UniProtKB | ChEBI)
Binding site599Ca2+ 16 (UniProtKB | ChEBI)
Binding site646Ca2+ 16 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Biological Processhomophilic cell adhesion via plasma membrane adhesion molecules

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Protocadherin gamma B4
    • Protocadherin gamma subfamily B, 4

Gene names

    • Name
      Pcdhgb4

Organism names

  • Taxonomic identifier
  • Organism
  • Strain
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q91XX6

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane688-711Helical

Keywords

PTM/Processing

Features

Showing features for signal, chain, disulfide bond, glycosylation.

TypeIDPosition(s)Description
Signal1-30
ChainPRO_501509949431-912
Disulfide bond96↔102
Glycosylation223N-acetyl-D-glucosamine 1
Glycosylation223N-linked (GlcNAc...) asparagine
Glycosylation417N-acetyl-D-glucosamine 2
Glycosylation417N-linked (GlcNAc...) asparagine
Glycosylation468Mannose 1
Glycosylation468O-linked (Man...) serine
Glycosylation645Mannose 2
Glycosylation653Mannose 2
Glycosylation653O-linked (Man...) serine

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain29-133Cadherin
Domain134-242Cadherin
Domain243-345Cadherin
Domain354-450Cadherin
Domain451-560Cadherin
Domain576-673Cadherin
Region782-821Disordered
Region882-912Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    912
  • Mass (Da)
    99,243
  • Last updated
    2001-12-01 v1
  • Checksum
    BFD952F754578C68
MREGTAERGRGQRRPMLLPFLLPLFCPTLSEQIRYKIPEEMPTGSVVGNLAKDLGFSVQELPTRKLRISSEKPYFSVSSESGELLVSSRLDREQICGKKLMCALEFEAVAENPLNFYHLSVELEDINDHTPKFAHTSFELQISESSKPGTRFILGSAHDADIGTNSLQNYQLSPNDHFSLVNKEKSDGSKYPEMILKTALDREKQKLYHLTLTALDFGHPPLNSTAQIQVLVTDANDNPPVFSQDIYRVSLPENVYPGTTVLRVVATDQDEGVNSEITFSFSEAGQVTQFNLDSNTGEITTLHTLDFEEVKEYSLVLEAKDGGGMIAQCTVEIEVLDENDNVPEVLFQSLPDLIMEDAEPGTYIALLKTRDKDSGRNGEVICKLEGGAPFKILTSSGNTYKLVTDGVLDREQNPEYNITIRATDKGDPPLSSSSSVTLHIGDVNDNAPVFTKVSYLVHVAENNPPGASIAQVSASDPDLGANGQVTYYIIASDLEPESLWSYVTINAQSGVLFAQRAFDHEQLRSFQLTLQARDHGSPTLSANVSMRLLVGDRNDNAPRVLYPTLEPDGSALFDMVPRSAEPGYLVTKVVAVDADSGHNAWLSYHVLQASDPGLFSLGLRTGEVRTARALGDRDSARQRLLVAVRDGGQPPLSATATLHLIFADSLQEVLPDLSDDPLPPDPQSELQFYLVVALALISVLFLLAVILAIALRLRHSSSRKAWGCFQSEVVVPPNYSEGTLPYSYNLCAAEFNSLTCNDQLKSGQDLQFADSAGALFPLCNSNESTSHQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC138701
EMBL· GenBank· DDBJ
AAI38702.1
EMBL· GenBank· DDBJ
mRNA
AY013806
EMBL· GenBank· DDBJ
AAK26095.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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