Q91XX1 · Q91XX1_MOUSE

  • Protein
    Protocadherin gamma C3
  • Gene
    Pcdhgc3
  • Status
    UniProtKB unreviewed (TrEMBL)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    3/5

Function

function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.

Features

Showing features for binding site.

1934100200300400500600700800900
TypeIDPosition(s)Description
Binding site39Ca2+ 1 (UniProtKB | ChEBI)
Binding site40Ca2+ 1 (UniProtKB | ChEBI)
Binding site93Ca2+ 1 (UniProtKB | ChEBI)
Binding site95Ca2+ 2 (UniProtKB | ChEBI)
Binding site127Ca2+ 2 (UniProtKB | ChEBI)
Binding site128Ca2+ 2 (UniProtKB | ChEBI)
Binding site129Ca2+ 3 (UniProtKB | ChEBI)
Binding site130Ca2+ 2 (UniProtKB | ChEBI)
Binding site131Ca2+ 3 (UniProtKB | ChEBI)
Binding site146Ca2+ 4 (UniProtKB | ChEBI)
Binding site161Ca2+ 3 (UniProtKB | ChEBI)
Binding site163Ca2+ 3 (UniProtKB | ChEBI)
Binding site167Ca2+ 3 (UniProtKB | ChEBI)
Binding site203Ca2+ 4 (UniProtKB | ChEBI)
Binding site205Ca2+ 5 (UniProtKB | ChEBI)
Binding site218Ca2+ 3 (UniProtKB | ChEBI)
Binding site236Ca2+ 5 (UniProtKB | ChEBI)
Binding site237Ca2+ 5 (UniProtKB | ChEBI)
Binding site238Ca2+ 6 (UniProtKB | ChEBI)
Binding site239Ca2+ 4 (UniProtKB | ChEBI)
Binding site240Ca2+ 6 (UniProtKB | ChEBI)
Binding site255Ca2+ 7 (UniProtKB | ChEBI)
Binding site270Ca2+ 6 (UniProtKB | ChEBI)
Binding site272Ca2+ 6 (UniProtKB | ChEBI)
Binding site276Ca2+ 6 (UniProtKB | ChEBI)
Binding site311Ca2+ 9 (UniProtKB | ChEBI)
Binding site313Ca2+ 9 (UniProtKB | ChEBI)
Binding site326Ca2+ 6 (UniProtKB | ChEBI)
Binding site344Ca2+ 8 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentcell-cell junction
Cellular Componentmembrane
Cellular Componentplasma membrane
Molecular Functioncalcium ion binding
Biological Processcalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
Biological Processcell adhesion
Biological Processhomophilic cell adhesion via plasma membrane adhesion molecules
Biological Processnegative regulation of neuron apoptotic process
Biological Processsynapse organization

Keywords

Names & Taxonomy

Protein names

  • Submitted names
    • Protocadherin gamma C3
    • Protocadherin gamma subfamily C, 3

Gene names

    • Name
      Pcdhgc3

Organism names

  • Taxonomic identifier
  • Organism
  • Strains
    • C57BL/6
    • C57BL/6J
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q91XX1

Proteomes

Organism-specific databases

Subcellular Location

Cell membrane
; Single-pass type I membrane protein
Membrane
; Single-pass type I membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane692-718Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for signal, chain, disulfide bond.

TypeIDPosition(s)Description
Signal1-29
ChainPRO_501509949330-934
Disulfide bond98↔104

Proteomic databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Family & Domains

Features

Showing features for domain, region, compositional bias.

TypeIDPosition(s)Description
Domain29-135Cadherin
Domain136-244Cadherin
Domain245-352Cadherin
Domain353-457Cadherin
Domain458-567Cadherin
Domain580-685Cadherin
Region804-843Disordered
Compositional bias809-843Polar residues
Region904-934Disordered

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    934
  • Mass (Da)
    101,048
  • Last updated
    2001-12-01 v1
  • Checksum
    977C2D856EBE49E6
MVAEARSSGLVSPWRTVGVLLLLAALTEASTIIHYEILEERERGFPVGNVVTDLGLDLGSLSARRLRVVSGASRRFFEVNWETGEMFVNDRLDREELCGTLPSCTVTLELVVENPLELFSAEVVVQDINDNNPSFPTGEMKLEISEALAPGTRFPLESAHDPDVGSNSLQTYELSHNEYFALRVQTREDGTKYAELVLERALDWEREPSVQLVLTALDGGTPARSATLPIRITVLDANDNAPAFNQSLYRARVREDAPPGTRVAQVLATDLDEGLNGEIVYSFGSHNRAGVRELFALDLVTGVLTIKGRLDFEDTKLHEIYIQAKDKGANPEGAHCKVLVEVVDVNDNAPEITVTSVYSPVPEDAPLGTVIALLSVTDLDAGENGLVTCEVPPGLPFSLTSSLKNYFTLKTSAALDRETMPEYNLSITARDSGIPSLSALTTVKVQVSDINDNPPQSSQSSYDVYVEENNLPGVPILNLSVWDPDAPPNARLSFFLLEPGAETGLVSRYFTINRDNGVLTTLVPLDYEDQREFQLTAHINDGGTPVLATNISVNVFVTDRNDNAPQVLYPRPGQSSVEMLPRGTAAGHVVSRVVGWDADAGHNAWLSYSLLGAPNQSLFAVGLHTGQISTARPIQDTDSPRQILTVLISDSGEPLLSTTATLTVSVTEESPEARAEFPSGSAPREQNKNLTFYLLLSLILVSVGFAVTVLGVIIFKVYKWKRSRDLYRAPVSSLYRTPGPSLHADAVRGGLMPPHLYHQVYLTTDSRRSDPLLKKPGAASPLASRQNTLRSCDPVFYRQVLGAESAPPGQQAPPNTDWRFSQAQRPGTSGSQNGDETGTWPNNQFDTEMLQAMILASASEAADGSSTLGGGAGTMGLSARYGPQFTLQHVPDYRQNVYIPGSNATLTNAAGKRDGKAPAGGNGNKKKSGKKEKK

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A0A0A6YWM6A0A0A6YWM6_MOUSEPcdhgc378

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias809-843Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
BC059175
EMBL· GenBank· DDBJ
AAH59175.1
EMBL· GenBank· DDBJ
mRNA
AY013811
EMBL· GenBank· DDBJ
AAK26100.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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