Q91WU4 · TMCO4_MOUSE

  • Protein
    Transmembrane and coiled-coil domain-containing protein 4
  • Gene
    Tmco4
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at transcript level
  • Annotation score
    2/5

Function

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane

Protein family/group databases

Names & Taxonomy

Protein names

  • Recommended name
    Transmembrane and coiled-coil domain-containing protein 4

Gene names

    • Name
      Tmco4

Organism names

  • Taxonomic identifier
  • Strains
    • C57BL/6J
    • NOD
    • FVB/N
  • Taxonomic lineage
    Eukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus

Accessions

  • Primary accession
    Q91WU4
  • Secondary accessions
    • Q8BIX8
    • Q9D675

Proteomes

Organism-specific databases

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane200-220Helical
Transmembrane228-248Helical
Transmembrane343-363Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003051501-631Transmembrane and coiled-coil domain-containing protein 4

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Miscellaneous

Family & Domains

Features

Showing features for region, coiled coil, compositional bias.

TypeIDPosition(s)Description
Region1-27Disordered
Coiled coil156-183
Compositional bias555-594Polar residues
Region555-595Disordered

Sequence similarities

Belongs to the TMCO4 family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoform

Align isoforms (2)
  • Sequence status
    Complete

This entry describes 2 isoforms produced by Alternative splicing.

Q91WU4-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    631
  • Mass (Da)
    67,945
  • Last updated
    2007-10-02 v2
  • Checksum
    F00E35C1CB7EDE27
MATWNRPHPRQPVAPEPAAEDDSQQPLGRELSEANRFAYAALCGFSLSQLFPEPEQSSFCTEFVTGLVKWLHLSESVLPTIMAFASGLGGEGADIFAQTLLQDPILRDNPSAVSQDLLSFSLKNGHYDARARVLVCHVTSLLQVPMEELDILEEVFLESLKDAKEEESETAEASRKRKEKRRKWKRYLLIGLATVGGGTVIGVTGGLAAPLVAAGAATIIGSAGAAALGSVAGIAVMTSLFGAAGAGLTGYKMKKRVGAIEEFMFLPLTEGRQLHITIAITGWLGSGRYRTFNAPWMALARSQEQYCLAWEAKYLMELGNALETILSGLANMVAQEALKYTVLSGIVAALTWPASLLSVANVIDNPWGVCLHRSAEVGKHLAHILLSRQQGRRPVTLIGFSLGARVIYFCLQEMAQEQDCQGIIEDVVLLGAPVEGDPKHWEPFRNVVSGRIINGYCRGDWLLSFVYRTSSVQLRVAGLQPVLLQDRRMENVDLTSVVNGHLDYAKQMDAILKVVGIRTKPGWREKGLPLAPGSLPQEEPLQTAIVSTDEIILQDGQSQGPASEDSLKTTIPSSASQAQMPAGLNQSTEDSLSTAAAPAEGHLICSHGVGPNPLGCPDCTHGTQESCTELD

Q91WU4-2

Computationally mapped potential isoform sequences

There is 1 potential isoform mapped to this entry

View all
EntryEntry nameGene nameLength
A2ALL4A2ALL4_MOUSETmco456

Features

Showing features for sequence conflict, alternative sequence, compositional bias.

TypeIDPosition(s)Description
Sequence conflict81in Ref. 3; AAH13471
Sequence conflict163in Ref. 3; AAH13471
Alternative sequenceVSP_028243191-246in isoform 2
Alternative sequenceVSP_028244419-421in isoform 2
Alternative sequenceVSP_028245422-631in isoform 2
Sequence conflict524in Ref. 3; AAH13471
Sequence conflict551in Ref. 3; AAH13471
Compositional bias555-594Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AK014571
EMBL· GenBank· DDBJ
BAB29436.1
EMBL· GenBank· DDBJ
mRNA
AK029092
EMBL· GenBank· DDBJ
BAC26291.1
EMBL· GenBank· DDBJ
mRNA
AK054337
EMBL· GenBank· DDBJ
BAC35737.1
EMBL· GenBank· DDBJ
mRNA
AK170619
EMBL· GenBank· DDBJ
BAE41914.1
EMBL· GenBank· DDBJ
mRNA
AK171189
EMBL· GenBank· DDBJ
BAE42299.1
EMBL· GenBank· DDBJ
mRNA
AL805923
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
BC013471
EMBL· GenBank· DDBJ
AAH13471.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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