Q91VF6 · COQA1_MOUSE
- ProteinCollagen alpha-1(XXVI) chain
- GeneCol26a1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids440 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | collagen trimer | |
Cellular Component | endoplasmic reticulum | |
Cellular Component | extracellular matrix | |
Cellular Component | extracellular region | |
Cellular Component | Golgi apparatus | |
Biological Process | positive regulation of cell-substrate adhesion |
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameCollagen alpha-1(XXVI) chain
- Alternative names
Gene names
Organism names
- Organism
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Mammalia > Eutheria > Euarchontoglires > Glires > Rodentia > Myomorpha > Muroidea > Muridae > Murinae > Mus > Mus
Accessions
- Primary accessionQ91VF6
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond, glycosylation.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-20 | |||||
Sequence: MKLVLLLPWACCCLCGSALA | ||||||
Chain | PRO_0000007826 | 21-440 | Collagen alpha-1(XXVI) chain | |||
Sequence: TGFLYPFPAAALQQHGYPEQGAGSPGNGYSSRRHWCHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVSYRTLIRPTYRVSYRTVTALEWRCCPGFTGSNCEEECMNCTRLSDMSERLTTLEAKVLLLEAAEQPSGPDNDLPPPQSTPPTWNEDFLPDAIPIAHPGPRRRRPTGPAGPPGQMGPPGPAGPPGSKGEQGQTGEKGPVGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPGLLPNTPQGVLYSLQTPTDKENGDSQLNPAVVDTVLTGIPGPRGPPGPPGPPGPHGPPGPPGAPGSQGLVDERVVARPSGEPSVKEEEDKASAAEGEGVQQLREALKILAERVLILEHMIGVHDPLASPEGGSGQDAALRANLKMKRGGPRPDGILAALLGPDPAQKSADQAGDRK | ||||||
Disulfide bond | 56↔118 | |||||
Sequence: CHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVSYRTLIRPTYRVSYRTVTALEWRCC | ||||||
Glycosylation | 70 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N | ||||||
Disulfide bond | 83↔89 | |||||
Sequence: CRWPGPC | ||||||
Disulfide bond | 117↔126 | |||||
Sequence: CCPGFTGSNC | ||||||
Glycosylation | 132 | N-linked (GlcNAc...) asparagine | ||||
Sequence: N |
Post-translational modification
Hydroxylated on proline residues.
N-glycosylated.
Keywords
- PTM
Proteomic databases
PTM databases
Expression
Tissue specificity
Specifically expressed in the testis and ovary in adult tissues.
Developmental stage
At 9.5 dpc it is expressed in the somites and in mesenchymal cells of the head and the branchial arches. At 14.5 dpc it is expressed in the surrounding mesenchyme of the kidney and the inner ear. Expression is also observed in the spinal nerves and ganglia, the mesenchyme of the skull, the diaphragm, and the skeletal muscles.
Gene expression databases
Interaction
Subunit
Homotrimer or heterotrimer.
Protein-protein interaction databases
Miscellaneous
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 52-128 | EMI | ||||
Sequence: RRHWCHHTVTRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVSYRTLIRPTYRVSYRTVTALEWRCCPGFTGSNCEE | ||||||
Region | 157-362 | Disordered | ||||
Sequence: EQPSGPDNDLPPPQSTPPTWNEDFLPDAIPIAHPGPRRRRPTGPAGPPGQMGPPGPAGPPGSKGEQGQTGEKGPVGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPGLLPNTPQGVLYSLQTPTDKENGDSQLNPAVVDTVLTGIPGPRGPPGPPGPPGPHGPPGPPGAPGSQGLVDERVVARPSGEPSVKEEEDKASAAEGEG | ||||||
Compositional bias | 196-216 | Pro residues | ||||
Sequence: RPTGPAGPPGQMGPPGPAGPP | ||||||
Domain | 199-267 | Collagen-like 1 | ||||
Sequence: GPAGPPGQMGPPGPAGPPGSKGEQGQTGEKGPVGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPGLL | ||||||
Compositional bias | 233-265 | Pro residues | ||||
Sequence: PPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPG | ||||||
Compositional bias | 270-296 | Polar residues | ||||
Sequence: TPQGVLYSLQTPTDKENGDSQLNPAVV | ||||||
Domain | 302-334 | Collagen-like 2 | ||||
Sequence: GIPGPRGPPGPPGPPGPHGPPGPPGAPGSQGLV | ||||||
Compositional bias | 305-328 | Pro residues | ||||
Sequence: GPRGPPGPPGPPGPHGPPGPPGAP | ||||||
Compositional bias | 342-358 | Basic and acidic residues | ||||
Sequence: PSGEPSVKEEEDKASAA | ||||||
Region | 390-440 | Disordered | ||||
Sequence: LASPEGGSGQDAALRANLKMKRGGPRPDGILAALLGPDPAQKSADQAGDRK |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence & Isoform
- Sequence statusComplete
- Sequence processingThe displayed sequence is further processed into a mature form.
This entry describes 2 isoforms produced by Alternative splicing.
Q91VF6-1
This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
- Name1
- Length440
- Mass (Da)45,810
- Last updated2001-12-01 v1
- Checksum10843475F53A2BB0
Q91VF6-2
- Name2
- NoteMay be due to a competing acceptor splice site.
- Differences from canonical
- 94-95: Missing
Features
Showing features for alternative sequence, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Alternative sequence | VSP_008448 | 94-95 | in isoform 2 | |||
Sequence: Missing | ||||||
Compositional bias | 196-216 | Pro residues | ||||
Sequence: RPTGPAGPPGQMGPPGPAGPP | ||||||
Compositional bias | 233-265 | Pro residues | ||||
Sequence: PPGLLGPPGPRGLPGEMGRPGPPGPPGPAGSPG | ||||||
Compositional bias | 270-296 | Polar residues | ||||
Sequence: TPQGVLYSLQTPTDKENGDSQLNPAVV | ||||||
Compositional bias | 305-328 | Pro residues | ||||
Sequence: GPRGPPGPPGPPGPHGPPGPPGAP | ||||||
Compositional bias | 342-358 | Basic and acidic residues | ||||
Sequence: PSGEPSVKEEEDKASAA |
Keywords
- Coding sequence diversity
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB085837 EMBL· GenBank· DDBJ | BAB96760.1 EMBL· GenBank· DDBJ | mRNA | ||
AJ416092 EMBL· GenBank· DDBJ | CAC94779.1 EMBL· GenBank· DDBJ | mRNA | ||
BC075713 EMBL· GenBank· DDBJ | AAH75713.1 EMBL· GenBank· DDBJ | mRNA |