Q91VC3 · IF4A3_MOUSE
- ProteinEukaryotic initiation factor 4A-III
- GeneEif4a3
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids411 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Variants
Variant ID(s) | Position(s) | Change | Description | Clinical significance | Provenance | ||
---|---|---|---|---|---|---|---|
rs242066711 | 4 | N>K | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.38) Somatic: No Accession: NC_000077.7:g.119190811G>C Codon: AAC/AAG Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119190811G>C Locations: - p.Asn4Lys (Ensembl:ENSMUST00000026667) - c.12C>G (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs212652137 | 4 | N>T | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: NC_000077.7:g.119190812T>G Codon: AAC/ACC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119190812T>G Locations: - p.Asn4Thr (Ensembl:ENSMUST00000026667) - c.11A>C (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389223140 | 65 | Q>L | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119188679T>A Codon: CAG/CTG Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119188679T>A Locations: - p.Gln65Leu (Ensembl:ENSMUST00000026667) - c.194A>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs251013860 | 94 | V>I | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (1) Somatic: No Accession: NC_000077.7:g.119186922C>T Codon: GTC/ATC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119186922C>T Locations: - p.Val94Ile (Ensembl:ENSMUST00000026667) - c.280G>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389227766 | 149 | D>V | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119185456T>A Codon: GAC/GTC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119185456T>A Locations: - p.Asp149Val (Ensembl:ENSMUST00000026667) - c.446A>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389221427 | 182 | K>N | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: NC_000077.7:g.119185191C>A Codon: AAG/AAT Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119185191C>A Locations: - p.Lys182Asn (Ensembl:ENSMUST00000026667) - c.546G>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389223076 | 205 | Y>N | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119184833A>T Codon: TAC/AAC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119184833A>T Locations: - p.Tyr205Asn (Ensembl:ENSMUST00000026667) - c.613T>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389196616 | 241 | V>M | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119184725C>T Codon: GTG/ATG Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119184725C>T Locations: - p.Val241Met (Ensembl:ENSMUST00000026667) - c.721G>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389217620 | 264 | K>* | EVA | ||||
Consequence: stop gained Somatic: No Accession: NC_000077.7:g.119184462T>A Codon: AAA/TAA Consequence type: stop gained Cytogenetic band: 11q Genomic location: NC_000077.7:g.119184462T>A Locations: - p.Lys264Ter (Ensembl:ENSMUST00000026667) - c.790A>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389196591 | 309 | G>V | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119183702C>A Codon: GGA/GTA Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119183702C>A Locations: - p.Gly309Val (Ensembl:ENSMUST00000026667) - c.926G>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389238055 | 326 | G>V | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119183651C>A Codon: GGT/GTT Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119183651C>A Locations: - p.Gly326Val (Ensembl:ENSMUST00000026667) - c.977G>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389158063 | 328 | S>I | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119183645C>A Codon: AGC/ATC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119183645C>A Locations: - p.Ser328Ile (Ensembl:ENSMUST00000026667) - c.983G>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389185226 | 335 | D>A | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119179782T>G Codon: GAC/GCC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179782T>G Locations: - p.Asp335Ala (Ensembl:ENSMUST00000026667) - c.1004A>C (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389238064 | 364 | R>K | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.02) Somatic: No Accession: NC_000077.7:g.119179695C>T Codon: AGA/AAA Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179695C>T Locations: - p.Arg364Lys (Ensembl:ENSMUST00000026667) - c.1091G>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389211757 | 371 | Y>N | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119179594A>T Codon: TAT/AAT Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179594A>T Locations: - p.Tyr371Asn (Ensembl:ENSMUST00000026667) - c.1111T>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3403038220 | 387 | R>Q | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: NC_000077.7:g.119179545C>T Codon: CGG/CAG Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179545C>T Locations: - p.Arg387Gln (Ensembl:ENSMUST00000026667) - c.1160G>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3402179569 | 389 | L>R | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119179539A>C Codon: CTC/CGC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179539A>C Locations: - p.Leu389Arg (Ensembl:ENSMUST00000026667) - c.1166T>G (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389221506 | 393 | E>D | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0) Somatic: No Accession: NC_000077.7:g.119179526C>G Codon: GAG/GAC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179526C>G Locations: - p.Glu393Asp (Ensembl:ENSMUST00000026667) - c.1179G>C (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389238084 | 394 | Q>* | EVA | ||||
Consequence: stop gained Somatic: No Accession: NC_000077.7:g.119179525G>A Codon: CAG/TAG Consequence type: stop gained Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179525G>A Locations: - p.Gln394Ter (Ensembl:ENSMUST00000026667) - c.1180C>T (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389226215 | 408 | A>T | EVA | ||||
Consequence: missense Predictions: - SIFT: tolerated - low confidence (0.07) Somatic: No Accession: NC_000077.7:g.119179383C>T Codon: GCT/ACT Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179383C>T Locations: - p.Ala408Thr (Ensembl:ENSMUST00000026667) - c.1222G>A (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: | |||||||
rs3389192480 | 410 | L>V | EVA | ||||
Consequence: missense Predictions: - SIFT: deleterious - low confidence (0.01) Somatic: No Accession: NC_000077.7:g.119179377G>C Codon: CTC/GTC Consequence type: missense Cytogenetic band: 11q Genomic location: NC_000077.7:g.119179377G>C Locations: - p.Leu410Val (Ensembl:ENSMUST00000026667) - c.1228C>G (Ensembl:ENSMUST00000026667) Source type: large scale study Cross-references: |