Q90Y56 · Q90Y56_DANRE
- ProteinDelta-like protein
- Genejag2b
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids1254 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Putative Notch ligand involved in the mediation of Notch signaling.
GO annotations
all annotations | all molecular function | virus receptor activity | dna binding | rna binding | cytoskeletal motor activity | catalytic activity | gtpase activity | structural molecule activity | transporter activity | cytoskeletal protein binding | lipid binding | cyclase activity | antioxidant activity | oxidoreductase activity | transferase activity | hydrolase activity | lyase activity | isomerase activity | ligase activity | protein tag activity | cargo receptor activity | histone binding | protein folding chaperone | translation regulator activity | nutrient reservoir activity | receptor ligand activity | molecular transducer activity | molecular adaptor activity | toxin activity | cell adhesion mediator activity | molecular function regulator activity | virus coreceptor activity | catalytic activity, acting on a protein | catalytic activity, acting on dna | catalytic activity, acting on rna | molecular carrier activity | transcription regulator activity | general transcription initiation factor activity | molecular sensor activity | molecular sequestering activity | atp-dependent activity | other molecular function | all biological process | mitotic cell cycle | cytokinesis | cytoplasmic translation | immune system process | muscle system process | circulatory system process | renal system process | respiratory system process | carbohydrate metabolic process | generation of precursor metabolites and energy | dna replication | dna repair | dna recombination | chromatin organization | dna-templated transcription | regulation of dna-templated transcription | trna metabolic process | protein folding | protein glycosylation | amino acid metabolic process | modified amino acid metabolic process | lipid metabolic process | vitamin metabolic process | sulfur compound metabolic process | intracellular protein transport | nucleocytoplasmic transport | autophagy | inflammatory response | mitochondrion organization | cytoskeleton organization | microtubule-based movement | peroxisome organization | lysosome organization | chromosome segregation | cell adhesion | establishment or maintenance of cell polarity | programmed cell death | photosynthesis | mrna metabolic process | snrna metabolic process | vesicle-mediated transport | reproductive process | digestive system process | signaling | cell differentiation | protein catabolic process | extracellular matrix organization | regulatory ncrna-mediated gene silencing | telomere organization | cell junction organization | wound healing | ribosome biogenesis | cilium organization | anatomical structure development | cell motility | nervous system process | endocrine process | protein maturation | transmembrane transport | nucleobase-containing small molecule metabolic process | hepaticobiliary system process | membrane organization | protein-containing complex assembly | cell wall organization or biogenesis | nitrogen cycle metabolic process | protein localization to plasma membrane | defense response to other organism | detoxification | meiotic nuclear division | mitotic nuclear division | mitochondrial gene expression | carbohydrate derivative metabolic process | other biological process | all cellular component | nuclear chromosome | extracellular region | extracellular space | cell wall | nucleus | nuclear envelope | nucleoplasm | chromosome | nucleolus | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | lipid droplet | microtubule organizing center | cytosol | ribosome | cytoskeleton | plasma membrane | cilium | plastid | thylakoid | external encapsulating structure | extracellular matrix | cytoplasmic vesicle | organelle | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | membrane | |
Cellular Component | plasma membrane | |
Cellular Component | protein-containing complex | |
Molecular Function | calcium ion binding | |
Molecular Function | Notch binding | |
Biological Process | establishment or maintenance of epithelial cell apical/basal polarity | |
Biological Process | exocrine pancreas development | |
Biological Process | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules | |
Biological Process | intrahepatic bile duct development | |
Biological Process | liver development | |
Biological Process | Notch signaling pathway | |
Biological Process | pancreas development | |
Biological Process | pronephros development | |
Biological Process | spinal cord motor neuron differentiation | |
Biological Process | ventral spinal cord interneuron differentiation |
Keywords
- Molecular function
- Ligand
Names & Taxonomy
Protein names
- Recommended nameDelta-like protein
Gene names
Organism names
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Actinopterygii > Neopterygii > Teleostei > Ostariophysi > Cypriniformes > Danionidae > Danioninae > Danio
Accessions
- Primary accessionQ90Y56
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Membrane ; Single-pass type I membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 1084-1108 | Helical | ||||
Sequence: YLVPVLCVVLCVLWVFCVIVCVWWT |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Signal | 1-26 | |||||
Sequence: MWNCIRIRNWLPIACLLLTMWTKVSQ | ||||||
Chain | PRO_5035035566 | 27-1254 | Delta-like protein | |||
Sequence: SSGYFELQLIAVENVNGELWDGECCDSTRNSQDQRCVRDECDTYFKVCLKEYQSEVTTTGQCTFGSGSTDVLGGNIFSFKTAKNSPSKTSDVGKIIIPFHFAWPRSYTLILEAWDWDNSTQNNGEENLIERHIHASMVNPGDHWQSIRHPGITAHIEYRIRVRCDENYYGSKCNKQCRPRDDYFGHYRCDPSGNIVCLDGWMGEDCRTAICKQGCNLIHGGCAVPGECKCNYGWQGQFCDECLPYPGCLHGTCVMPWQCTCEKNWGGLLCDKDLNYCGTHHPCVNGGTCMNSEPDEYNCACPEGYSGKNCEIAEHACVSNPCANGGTCHEVPTGFECHCPPGWEGPTCAKDMDECASSPCAQGGTCIDLENGFECVCPPQWVGKTCQIDANECMGKPCVNAHSCKNMIGGYHCDCFQGWAGQNCDINLNGCHGQCQNGATCKELVHGGYHCQCPAGFVGLHCEVSRNKCASGPCQNGGRCHVILDSFVCECPSNYAGMLCEVESLSHPNPCEPNPCQNTALCYSLPGDFYCACPEDYEGKTCENRKDHCKMTPCQVIDSCTIAVASNSSDGGVRHINSNVCGPHGRCISQPGGNFTCTCELGFTGTYCHENVNDCVSNPCRNGGTCIDGISSFQCFCPDGWEGDLCSINVNECSRSPCKNGGHCVDLVNDFYCECANGWKGKTCHSRESQCDSSTCSNGGTCYDHGDAFRCACPPGWEGSTCNTAKNSTCASGPCLNGGTCVGGGDTFTCICKDGWEGATCAQNTNDCNPHPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGFRCVCPLGRTGPQCQEFIGIGKTCHYAGLQFPHGSRWEEECNTCQCVNGKVECTKVVCGRKPCLLPGTPGRELHYCPGGRECLEHNFLTCLSPPCHQWGFCSSPETPPTLQTKCEPNSVYLDKSCARITLIFNRDKLPTGTTVENVCSELRYMPATRSLAKDHKLLVLCDLSYKNQDAVEVAISFQHDEQPSHSQIQEAASTIVSTLSKRHNSTVMLAVIEVKVEMPVTSQPVDYLVPVLCVVLCVLWVFCVIVCVWWTRKRRKERERRERVPVEESVNNQWEPLRPVTRPQHKDNRDAQFERTKLMGSPDRTCNSGDDEEDMEEDELELVEEWCGTEGGKHPVQKYSKSAARTKNGLICTTRSTSGSSSPSLKAAYWTGFSPKDNNCKNVNNATAGQEHKEHCV | ||||||
Disulfide bond | 190↔199 | |||||
Sequence: CDENYYGSKC | ||||||
Disulfide bond | 203↔215 | |||||
Sequence: CRPRDDYFGHYRC | ||||||
Disulfide bond | 223↔232 | |||||
Sequence: CLDGWMGEDC | ||||||
Disulfide bond | 327↔336 | |||||
Sequence: CPEGYSGKNC | ||||||
Disulfide bond | 365↔374 | |||||
Sequence: CPPGWEGPTC | ||||||
Disulfide bond | 403↔412 | |||||
Sequence: CPPQWVGKTC | ||||||
Disulfide bond | 441↔450 | |||||
Sequence: CFQGWAGQNC | ||||||
Disulfide bond | 457↔467 | |||||
Sequence: CHGQCQNGATC | ||||||
Disulfide bond | 479↔488 | |||||
Sequence: CPAGFVGLHC | ||||||
Disulfide bond | 517↔526 | |||||
Sequence: CPSNYAGMLC | ||||||
Disulfide bond | 559↔568 | |||||
Sequence: CPEDYEGKTC | ||||||
Disulfide bond | 625↔634 | |||||
Sequence: CELGFTGTYC | ||||||
Disulfide bond | 663↔672 | |||||
Sequence: CPDGWEGDLC | ||||||
Disulfide bond | 701↔710 | |||||
Sequence: CANGWKGKTC | ||||||
Disulfide bond | 739↔748 | |||||
Sequence: CPPGWEGSTC | ||||||
Disulfide bond | 778↔787 | |||||
Sequence: CKDGWEGATC | ||||||
Disulfide bond | 816↔825 | |||||
Sequence: CAPGFAGPDC | ||||||
Disulfide bond | 854↔863 | |||||
Sequence: CPLGRTGPQC |
Keywords
- PTM
Structure
Family & Domains
Features
Showing features for domain, region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 188-232 | DSL | ||||
Sequence: VRCDENYYGSKCNKQCRPRDDYFGHYRCDPSGNIVCLDGWMGEDC | ||||||
Domain | 299-337 | EGF-like | ||||
Sequence: DLNYCGTHHPCVNGGTCMNSEPDEYNCACPEGYSGKNCE | ||||||
Domain | 339-375 | EGF-like | ||||
Sequence: AEHACVSNPCANGGTCHEVPTGFECHCPPGWEGPTCA | ||||||
Domain | 377-413 | EGF-like | ||||
Sequence: DMDECASSPCAQGGTCIDLENGFECVCPPQWVGKTCQ | ||||||
Domain | 415-451 | EGF-like | ||||
Sequence: DANECMGKPCVNAHSCKNMIGGYHCDCFQGWAGQNCD | ||||||
Domain | 453-489 | EGF-like | ||||
Sequence: NLNGCHGQCQNGATCKELVHGGYHCQCPAGFVGLHCE | ||||||
Domain | 491-527 | EGF-like | ||||
Sequence: SRNKCASGPCQNGGRCHVILDSFVCECPSNYAGMLCE | ||||||
Domain | 533-569 | EGF-like | ||||
Sequence: HPNPCEPNPCQNTALCYSLPGDFYCACPEDYEGKTCE | ||||||
Domain | 596-635 | EGF-like | ||||
Sequence: DGGVRHINSNVCGPHGRCISQPGGNFTCTCELGFTGTYCH | ||||||
Domain | 637-673 | EGF-like | ||||
Sequence: NVNDCVSNPCRNGGTCIDGISSFQCFCPDGWEGDLCS | ||||||
Domain | 675-711 | EGF-like | ||||
Sequence: NVNECSRSPCKNGGHCVDLVNDFYCECANGWKGKTCH | ||||||
Domain | 713-749 | EGF-like | ||||
Sequence: RESQCDSSTCSNGGTCYDHGDAFRCACPPGWEGSTCN | ||||||
Domain | 752-788 | EGF-like | ||||
Sequence: KNSTCASGPCLNGGTCVGGGDTFTCICKDGWEGATCA | ||||||
Domain | 790-826 | EGF-like | ||||
Sequence: NTNDCNPHPCYNGGICVDGVNWFRCECAPGFAGPDCR | ||||||
Domain | 828-864 | EGF-like | ||||
Sequence: NIDECQSSPCAYGATCVDEINGFRCVCPLGRTGPQCQ | ||||||
Region | 1135-1170 | Disordered | ||||
Sequence: RPVTRPQHKDNRDAQFERTKLMGSPDRTCNSGDDEE | ||||||
Compositional bias | 1137-1154 | Basic and acidic residues | ||||
Sequence: VTRPQHKDNRDAQFERTK |
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length1,254
- Mass (Da)137,720
- Last updated2001-12-01 v1
- ChecksumAFF70717DF190FEB
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
Q5TZK7 | Q5TZK7_DANRE | jag2b | 1216 |
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 1137-1154 | Basic and acidic residues | ||||
Sequence: VTRPQHKDNRDAQFERTK |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AF229449 EMBL· GenBank· DDBJ | AAL08214.1 EMBL· GenBank· DDBJ | mRNA |