Q90855 · Q90855_CHICK
- ProteinGlutamate receptor
- GeneGluR1
- StatusUniProtKB unreviewed (TrEMBL)
- Organism
- Amino acids902 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score5/5
Function
function
Receptor for glutamate that functions as a ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system.
Features
Showing features for site, binding site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Site | 467 | Interaction with the cone snail toxin Con-ikot-ikot | |||
Binding site | 492 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 494 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 499 | L-glutamate (UniProtKB | ChEBI) | |||
Site | 647 | Crucial to convey clamshell closure to channel opening | |||
Binding site | 668 | L-glutamate (UniProtKB | ChEBI) | |||
Binding site | 669 | L-glutamate (UniProtKB | ChEBI) | |||
Site | 674 | Interaction with the cone snail toxin Con-ikot-ikot | |||
Binding site | 719 | L-glutamate (UniProtKB | ChEBI) | |||
Site | 766 | Interaction with the cone snail toxin Con-ikot-ikot | |||
GO annotations
Keywords
- Molecular function
- Biological process
Names & Taxonomy
Protein names
- Recommended nameGlutamate receptor
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Chordata > Craniata > Vertebrata > Euteleostomi > Archelosauria > Archosauria > Dinosauria > Saurischia > Theropoda > Coelurosauria > Aves > Neognathae > Galloanserae > Galliformes > Phasianidae > Phasianinae > Gallus
Accessions
- Primary accessionQ90855
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Transmembrane | 535-557 | Helical | |||
Transmembrane | 618-640 | Helical | |||
Transmembrane | 808-830 | Helical | |||
Keywords
- Cellular component
PTM/Processing
Features
Showing features for signal, chain, disulfide bond.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Signal | 1-18 | ||||
Chain | PRO_5014312418 | 19-902 | Glutamate receptor | ||
Disulfide bond | 75↔323 | ||||
Disulfide bond | 732↔787 | ||||
Keywords
- PTM
Proteomic databases
Expression
Gene expression databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Domain | 408-783 | Ionotropic glutamate receptor C-terminal | |||
Domain | 418-483 | Ionotropic glutamate receptor L-glutamate and glycine-binding | |||
Sequence similarities
Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family.
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length902
- Mass (Da)101,689
- Last updated1996-11-01 v1
- ChecksumD1487E544D8B4CB4
Computationally mapped potential isoform sequences
There is 1 potential isoform mapped to this entry
Entry | Entry name | Gene name | Length | ||
---|---|---|---|---|---|
A0A1D5PIW7 | A0A1D5PIW7_CHICK | GRIA1 | 902 |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
X89510 EMBL· GenBank· DDBJ | CAA61681.1 EMBL· GenBank· DDBJ | mRNA |