Q8ZLV8 · Q8ZLV8_SALTY
- Protein2-hydroxy-3-oxopropionate reductase
- GenegarR
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids296 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score3/5
Function
function
Catalyzes the reduction of tatronate semialdehyde to D-glycerate.
Catalytic activity
- (R)-glycerate + NAD+ = 2-hydroxy-3-oxopropanoate + H+ + NADH
Pathway
Carbohydrate acid metabolism; galactarate degradation; D-glycerate from galactarate: step 3/3.
Features
Showing features for binding site, active site.
GO annotations
Aspect | Term | |
---|---|---|
Molecular Function | 2-hydroxy-3-oxopropionate reductase activity | |
Molecular Function | NAD binding | |
Molecular Function | NADP binding | |
Biological Process | galactarate catabolic process | |
Biological Process | glyoxylate metabolic process |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended name2-hydroxy-3-oxopropionate reductase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionQ8ZLV8
Proteomes
PTM/Processing
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for domain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Domain | 4-163 | 6-phosphogluconate dehydrogenase NADP-binding | ||||
Sequence: KVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIADVIAAGAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLASREISDALKAKGVEMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVVHTG | ||||||
Domain | 166-283 | 3-hydroxyisobutyrate dehydrogenase-like NAD-binding | ||||
Sequence: GAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLDAKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGHGNDDHSALA |
Sequence similarities
Belongs to the HIBADH-related family. 2-hydroxy-3-oxopropionate reductase subfamily.
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length296
- Mass (Da)30,729
- Last updated2002-03-01 v1
- ChecksumA62B62F3B91F9DFC
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006468 EMBL· GenBank· DDBJ | AAL22120.1 EMBL· GenBank· DDBJ | Genomic DNA |