Q8ZLG7 · Q8ZLG7_SALTY
- ProteinAlpha-1,4 glucan phosphorylase
- GeneglgP
- StatusUniProtKB unreviewed (TrEMBL)
- Amino acids815 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis.
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Catalytic activity
- [(1->4)-alpha-D-glucosyl](n) + phosphate = [(1->4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate
[(1→4)-α-D-glucosyl](n) RHEA-COMP:9584 + CHEBI:43474 = [(1→4)-α-D-glucosyl](n-1) RHEA-COMP:9586 + CHEBI:58601
Cofactor
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | glycogen phosphorylase activity | |
Molecular Function | linear malto-oligosaccharide phosphorylase activity | |
Molecular Function | pyridoxal phosphate binding | |
Molecular Function | SHG alpha-glucan phosphorylase activity | |
Biological Process | glycogen catabolic process |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended nameAlpha-1,4 glucan phosphorylase
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionQ8ZLG7
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
PTM/Processing
Features
Showing features for modified residue.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Modified residue | 662 | N6-(pyridoxal phosphate)lysine | ||||
Sequence: K |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length815
- Mass (Da)93,343
- Last updated2002-03-01 v1
- Checksum4464A9CBB044F1C2
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006468 EMBL· GenBank· DDBJ | AAL22394.1 EMBL· GenBank· DDBJ | Genomic DNA |