Q8ZKP8 · LSRE_SALTY
- ProteinPutative epimerase LsrE
- GenelsrE
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids254 (go to sequence)
- Protein existenceEvidence at transcript level
- Annotation score3/5
Function
Cofactor
Note: Binds 1 divalent metal cation per subunit.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Binding site | 50 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Active site | 52 | Proton acceptor | ||||
Sequence: D | ||||||
Binding site | 52 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 81 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: H | ||||||
Binding site | 81 | substrate | ||||
Sequence: H | ||||||
Binding site | 166-169 | substrate | ||||
Sequence: GYGS | ||||||
Active site | 199 | Proton donor | ||||
Sequence: D | ||||||
Binding site | 199 | a divalent metal cation (UniProtKB | ChEBI) | ||||
Sequence: D | ||||||
Binding site | 199-201 | substrate | ||||
Sequence: DGS | ||||||
Binding site | 221-222 | substrate | ||||
Sequence: GS |
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytosol | |
Cellular Component | plasma membrane | |
Molecular Function | D-ribulose-phosphate 3-epimerase activity | |
Molecular Function | metal ion binding | |
Biological Process | carbohydrate metabolic process | |
Biological Process | pentose-phosphate shunt, non-oxidative branch |
Keywords
- Molecular function
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended namePutative epimerase LsrE
- EC number
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Enterobacteriaceae > Salmonella
Accessions
- Primary accessionQ8ZKP8
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Single-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 14-34 | Helical | ||||
Sequence: VALLASYPLSVGILAGQWIAL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000351561 | 1-254 | Putative epimerase LsrE | |||
Sequence: MNSQFAGLTREACVALLASYPLSVGILAGQWIALHRYLQQLEALNQPLLHLDLMDGQFCPQFTVGPWAVGQLPQTFIKDVHLMVADQWTAAQACVKAGAHCITLQAEGDIHLHHTLSWLGQQTVPVIGGEMPVIRGISLCPATPLDVIIPILSDVEVIQLLAVNPGYGSKMRSSDLHERVAQLLCLLGDKREGKIIVIDGSLTQDQLPSLIAQGIDRVVSGSALFRDDRLVENTRSWRAMFKVAGDTTFLPSTA |
Proteomic databases
Expression
Induction
In the absence of AI-2, repressed by LsrR. Induced by AI-2, via release of the LsrR repressor.
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length254
- Mass (Da)27,635
- Last updated2002-03-01 v1
- ChecksumF8272A0A05F15451
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AE006468 EMBL· GenBank· DDBJ | AAL22920.1 EMBL· GenBank· DDBJ | Genomic DNA |