Q8ZDB1 · FLUC3_YERPE
- ProteinFluoride-specific ion channel FluC 3
- GenefluC3
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids126 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.
Catalytic activity
- fluoride(in) = fluoride(out)This reaction proceeds in the forward direction.
Activity regulation
Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.
Features
Showing features for binding site.
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | fluoride channel activity | |
Molecular Function | fluoride transmembrane transporter activity | |
Molecular Function | metal ion binding | |
Biological Process | cellular detoxification of fluoride | |
Biological Process | fluoride transmembrane transport |
Keywords
- Molecular function
- Biological process
- Ligand
Names & Taxonomy
Protein names
- Recommended nameFluoride-specific ion channel FluC 3
Gene names
Organism names
- Organism
- Strains
- Taxonomic lineageBacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Yersinia
Accessions
- Primary accessionQ8ZDB1
- Secondary accessions
Proteomes
Subcellular Location
UniProt Annotation
GO Annotation
Cell inner membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 7-27 | Helical | ||||
Sequence: MWVGLGGGIGSLLRWWIGLSI | ||||||
Transmembrane | 37-57 | Helical | ||||
Sequence: LGTFLINISGAFVIGYLSILF | ||||||
Transmembrane | 68-87 | Helical | ||||
Sequence: LMNTAVLTGILGGYTTFSSM | ||||||
Transmembrane | 101-121 | Helical | ||||
Sequence: AIAAGYLIISVLVGLAAAAFG |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000110217 | 1-126 | Fluoride-specific ion channel FluC 3 | |||
Sequence: MTAIDVMWVGLGGGIGSLLRWWIGLSIGKVYKGNFPLGTFLINISGAFVIGYLSILFSVDWRDRYGDLMNTAVLTGILGGYTTFSSMQLDAAKLATARGRAIAAGYLIISVLVGLAAAAFGAWLAY |
Proteomic databases
Interaction
Protein-protein interaction databases
Structure
Sequence
- Sequence statusComplete
- Length126
- Mass (Da)13,345
- Last updated2002-03-01 v1
- Checksum871E4217B3F2C707
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AL590842 EMBL· GenBank· DDBJ | CAL21296.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE009952 EMBL· GenBank· DDBJ | AAM84823.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AE017042 EMBL· GenBank· DDBJ | AAS62677.1 EMBL· GenBank· DDBJ | Genomic DNA |