Q8ZDB1 · FLUC3_YERPE

  • Protein
    Fluoride-specific ion channel FluC 3
  • Gene
    fluC3
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Inferred from homology
  • Annotation score
    3/5

Function

function

Fluoride-specific ion channel. Important for reducing fluoride concentration in the cell, thus reducing its toxicity.

Catalytic activity

Activity regulation

Na+ is not transported, but it plays an essential structural role and its presence is essential for fluoride channel function.

Features

Showing features for binding site.

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TypeIDPosition(s)Description
Binding site79Na+ (UniProtKB | ChEBI); structural
Binding site82Na+ (UniProtKB | ChEBI); structural

GO annotations

AspectTerm
Cellular Componentplasma membrane
Molecular Functionfluoride channel activity
Molecular Functionfluoride transmembrane transporter activity
Molecular Functionmetal ion binding
Biological Processcellular detoxification of fluoride
Biological Processfluoride transmembrane transport

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Fluoride-specific ion channel FluC 3

Gene names

    • Name
      fluC3
    • Synonyms
      crcB3
    • Ordered locus names
      YPO2677, y1249, YP_2478

Organism names

  • Taxonomic identifier
  • Strains
    • CO-92 / Biovar Orientalis
    • KIM10+ / Biovar Mediaevalis
    • 91001 / Biovar Mediaevalis
  • Taxonomic lineage
    Bacteria > Pseudomonadota > Gammaproteobacteria > Enterobacterales > Yersiniaceae > Yersinia

Accessions

  • Primary accession
    Q8ZDB1
  • Secondary accessions
    • Q0WDL3

Proteomes

Subcellular Location

Cell inner membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane7-27Helical
Transmembrane37-57Helical
Transmembrane68-87Helical
Transmembrane101-121Helical

Keywords

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00001102171-126Fluoride-specific ion channel FluC 3

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the fluoride channel Fluc/FEX (TC 1.A.43) family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    126
  • Mass (Da)
    13,345
  • Last updated
    2002-03-01 v1
  • Checksum
    871E4217B3F2C707
MTAIDVMWVGLGGGIGSLLRWWIGLSIGKVYKGNFPLGTFLINISGAFVIGYLSILFSVDWRDRYGDLMNTAVLTGILGGYTTFSSMQLDAAKLATARGRAIAAGYLIISVLVGLAAAAFGAWLAY

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL590842
EMBL· GenBank· DDBJ
CAL21296.1
EMBL· GenBank· DDBJ
Genomic DNA
AE009952
EMBL· GenBank· DDBJ
AAM84823.1
EMBL· GenBank· DDBJ
Genomic DNA
AE017042
EMBL· GenBank· DDBJ
AAS62677.1
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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