Q8YQD7 · COAX_NOSS1
- ProteinType III pantothenate kinase
- GenecoaX
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids276 (go to sequence)
- Protein existenceInferred from homology
- Annotation score3/5
Function
function
Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
Catalytic activity
- (R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H+
Cofactor
K+ (UniProtKB | Rhea| CHEBI:29103 )
Note: A monovalent cation. Ammonium or potassium.
Pathway
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 18-25 | ATP (UniProtKB | ChEBI) | |||
Binding site | 116 | substrate | |||
Binding site | 120-123 | substrate | |||
Active site | 122 | Proton acceptor | |||
Binding site | 142 | K+ (UniProtKB | ChEBI) | |||
Binding site | 145 | ATP (UniProtKB | ChEBI) | |||
Binding site | 200 | substrate | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | cytoplasm | |
Molecular Function | ATP binding | |
Molecular Function | metal ion binding | |
Molecular Function | pantothenate kinase activity | |
Biological Process | coenzyme A biosynthetic process | |
Biological Process | phosphorylation |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameType III pantothenate kinase
- EC number
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageBacteria > Cyanobacteriota > Cyanophyceae > Nostocales > Nostocaceae > Nostoc
Accessions
- Primary accessionQ8YQD7
Proteomes
Subcellular Location
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000270857 | 1-276 | Type III pantothenate kinase | ||
Interaction
Structure
Sequence
- Sequence statusComplete
- Length276
- Mass (Da)30,272
- Last updated2002-03-01 v1
- MD5 ChecksumD242EB0FA372E31E37043C2DDFDB884D
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
BA000019 EMBL· GenBank· DDBJ | BAB75595.1 EMBL· GenBank· DDBJ | Genomic DNA |