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Q8X176 · PHOA_ASPFU

Function

function

Has both phosphomonoesterase and phosphodiesterase activity. Cleaves a broad range of phosphate esters.

Catalytic activity

Activity regulation

Inhibited by NaF, molybdate and vanadate.

Kinetics

KM SUBSTRATE pH TEMPERATURE[C] NOTES EVIDENCE
1.45 mMp-nitrophenyl phosphate
2.3 mMbis-(p-nitrophenyl) phosphate

pH Dependence

Optimum pH is 4-6. Active from pH 3 to 7.

Features

Showing features for active site.

TypeIDPosition(s)Description
Active site215Proton donor

GO annotations

AspectTerm
Cellular Componentplasma membrane
Cellular Componentside of membrane
Molecular Functionacid phosphatase activity
Biological Processcell wall organization
Biological Processphospholipid catabolic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

Gene names

    • Name
      phoA
    • ORF names
      AFUA_1G03570

Organism names

Accessions

  • Primary accession
    Q8X176
  • Secondary accessions
    • Q4WK63

Proteomes

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for signal, chain, glycosylation, lipidation, propeptide.

Type
IDPosition(s)Description
Signal1-17
ChainPRO_000024556018-419Acid phosphatase
Glycosylation119N-linked (GlcNAc...) asparagine
Glycosylation150N-linked (GlcNAc...) asparagine
Glycosylation177N-linked (GlcNAc...) asparagine
Glycosylation186N-linked (GlcNAc...) asparagine
Glycosylation208N-linked (GlcNAc...) asparagine
Glycosylation217N-linked (GlcNAc...) asparagine
Glycosylation234N-linked (GlcNAc...) asparagine
Glycosylation240N-linked (GlcNAc...) asparagine
Glycosylation315N-linked (GlcNAc...) asparagine
Glycosylation332N-linked (GlcNAc...) asparagine
Glycosylation382N-linked (GlcNAc...) asparagine
Glycosylation405N-linked (GlcNAc...) asparagine
Lipidation419GPI-like-anchor amidated serine
PropeptidePRO_0000245561420-447Removed in mature form

Post-translational modification

The GPI-like anchor contains a phosphoceramide lipid group. The anchor position has not been determined.

Keywords

PTM databases

Expression

Induction

Repressed by phosphate.

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Sequence processing
    The displayed sequence is further processed into a mature form.
  • Length
    447
  • Mass (Da)
    48,988
  • Last updated
    2002-03-01 v1
  • MD5 Checksum
    572FA219DE776A2C3F50CF8511837015
MKPSVATLLATVSLVYAQTATEKEPSLSAIESAAASIQPYSPVSNVEGVAFNRFFQVWLENIDYEDAAADENMKWLASQGILLTNFYAVTHPSEPNYCAAVGGDTFGMDNDNFNQIPANVSTVADLLDTKNIAWGEYQEHLPYPGFQGFNYSNQETYVNDYVRKHNPLVLYDSVTKNSTRLRQIKNFTSFEDDLANKKLPQWAFITPNMTNDAHDTNITFGAKWERSWIAPLLNNSYFMNDTLILLTFDEDGTYSKSNKIFSVLLGGAIPDELKGTQDDTFYTHYSVIASVSANWGLPSLGRWDCGANILEIVANKTGYVNYDVDTTNLRLNETYPGPMSAGEYSKYSPVWPNALTRGDCSAGHGILDIVKETYANTEPTYNYSSPFPYDTASNYNTKVTATKKNVTGTHRSSSSSSPSASSNAAVSAVAPAAGVSGLLLGLALNLL

Sequence caution

The sequence EAL88069.1 differs from that shown. Reason: Erroneous gene model prediction

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict329in Ref. 3; AA sequence

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF462065
EMBL· GenBank· DDBJ
AAL66381.1
EMBL· GenBank· DDBJ
Genomic DNA
AAHF01000007
EMBL· GenBank· DDBJ
EAL88069.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.

Genome annotation databases

Similar Proteins

Disclaimer

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