Q8WQL7 · MBK1_CAEEL
- ProteinDual specificity tyrosine-phosphorylation-regulated kinase mbk-1
- Genembk-1
- StatusUniProtKB reviewed (Swiss-Prot)
- Organism
- Amino acids882 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Possible role in the function of olfactory neurons.
Catalytic activity
- L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H+
Cofactor
Features
Showing features for binding site, active site.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Binding site | 334-342 | ATP (UniProtKB | ChEBI) | |||
Binding site | 357 | ATP (UniProtKB | ChEBI) | |||
Active site | 456 | Proton acceptor | |||
GO annotations
Aspect | Term | |
---|---|---|
Cellular Component | nucleus | |
Molecular Function | ATP binding | |
Molecular Function | protein serine kinase activity | |
Molecular Function | protein serine/threonine kinase activity | |
Molecular Function | protein serine/threonine/tyrosine kinase activity | |
Molecular Function | protein tyrosine kinase activity | |
Molecular Function | transcription coactivator activity | |
Biological Process | positive regulation of DNA-templated transcription | |
Biological Process | protein autophosphorylation | |
Biological Process | sensory perception of smell |
Keywords
- Molecular function
- Biological process
- Ligand
Enzyme and pathway databases
Names & Taxonomy
Protein names
- Recommended nameDual specificity tyrosine-phosphorylation-regulated kinase mbk-1
- EC number
- Alternative names
Gene names
Organism names
- Organism
- Strain
- Taxonomic lineageEukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis
Accessions
- Primary accessionQ8WQL7
- Secondary accessions
Proteomes
Organism-specific databases
Subcellular Location
Phenotypes & Variants
Disruption phenotype
No visible phenotype.
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Chain | PRO_0000390715 | 1-882 | Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1 | ||
Proteomic databases
Expression
Tissue specificity
Expressed in all somatic cells.
Developmental stage
First observed during early cell morphogenesis in the embryo, levels increase during later embryonic development and remain at comparable levels throughout larval and adult stages.
Gene expression databases
Interaction
Binary interactions
Type | Entry 1 | Entry 2 | Number of experiments | IntAct | |
---|---|---|---|---|---|
BINARY | Q8WQL7 | gei-18 Q7K7J0 | 3 | EBI-329013, EBI-2315822 |
Protein-protein interaction databases
Structure
Family & Domains
Features
Showing features for region, compositional bias, domain.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Region | 1-45 | Disordered | |||
Region | 62-81 | Disordered | |||
Compositional bias | 212-227 | Basic and acidic residues | |||
Region | 212-239 | Disordered | |||
Compositional bias | 255-305 | Polar residues | |||
Region | 255-308 | Disordered | |||
Domain | 328-649 | Protein kinase | |||
Region | 742-761 | Disordered | |||
Compositional bias | 789-814 | Polar residues | |||
Region | 789-882 | Disordered | |||
Compositional bias | 815-838 | Basic and acidic residues | |||
Compositional bias | 839-868 | Polar residues | |||
Sequence similarities
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length882
- Mass (Da)101,244
- Last updated2002-03-01 v1
- MD5 Checksum2ABCE09B53055E609E9B18FC3C334BCC
Features
Showing features for compositional bias.
Type | ID | Position(s) | Description | ||
---|---|---|---|---|---|
Compositional bias | 212-227 | Basic and acidic residues | |||
Compositional bias | 255-305 | Polar residues | |||
Compositional bias | 789-814 | Polar residues | |||
Compositional bias | 815-838 | Basic and acidic residues | |||
Compositional bias | 839-868 | Polar residues | |||
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AY064464 EMBL· GenBank· DDBJ | AAL40874.1 EMBL· GenBank· DDBJ | mRNA | ||
Z69885 EMBL· GenBank· DDBJ | CAA93756.2 EMBL· GenBank· DDBJ | Genomic DNA |