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Q8WQL7 · MBK1_CAEEL

  • Protein
    Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1
  • Gene
    mbk-1
  • Status
    UniProtKB reviewed (Swiss-Prot)
  • Amino acids
  • Protein existence
    Evidence at protein level
  • Annotation score
    5/5

Function

function

Possible role in the function of olfactory neurons.

Catalytic activity

Cofactor

Mg2+ (UniProtKB | Rhea| CHEBI:18420 )

Features

Showing features for binding site, active site.

Type
IDPosition(s)Description
Binding site334-342ATP (UniProtKB | ChEBI)
Binding site357ATP (UniProtKB | ChEBI)
Active site456Proton acceptor

GO annotations

AspectTerm
Cellular Componentnucleus
Molecular FunctionATP binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Molecular Functionprotein serine/threonine/tyrosine kinase activity
Molecular Functionprotein tyrosine kinase activity
Molecular Functiontranscription coactivator activity
Biological Processpositive regulation of DNA-templated transcription
Biological Processprotein autophosphorylation
Biological Processsensory perception of smell

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1
  • EC number
  • Alternative names
    • Dual specificity Yak1-related kinase mbk-1
    • Minibrain Kinase 1

Gene names

    • Name
      mbk-1
    • ORF names
      T04C10.1

Organism names

  • Taxonomic identifier
  • Strain
    • Bristol N2
  • Taxonomic lineage
    Eukaryota > Metazoa > Ecdysozoa > Nematoda > Chromadorea > Rhabditida > Rhabditina > Rhabditomorpha > Rhabditoidea > Rhabditidae > Peloderinae > Caenorhabditis

Accessions

  • Primary accession
    Q8WQL7
  • Secondary accessions
    • Q22155

Proteomes

Organism-specific databases

Subcellular Location

Keywords

Phenotypes & Variants

Disruption phenotype

No visible phenotype.

PTM/Processing

Features

Showing features for chain.

TypeIDPosition(s)Description
ChainPRO_00003907151-882Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1

Proteomic databases

Expression

Tissue specificity

Expressed in all somatic cells.

Developmental stage

First observed during early cell morphogenesis in the embryo, levels increase during later embryonic development and remain at comparable levels throughout larval and adult stages.

Gene expression databases

    • WBGene00003149Expressed in pharyngeal muscle cell (C elegans) and 4 other cell types or tissues

Interaction

Binary interactions

TypeEntry 1Entry 2Number of experimentsIntAct
BINARY Q8WQL7gei-18 Q7K7J03EBI-329013, EBI-2315822

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for region, compositional bias, domain.

Type
IDPosition(s)Description
Region1-45Disordered
Region62-81Disordered
Compositional bias212-227Basic and acidic residues
Region212-239Disordered
Compositional bias255-305Polar residues
Region255-308Disordered
Domain328-649Protein kinase
Region742-761Disordered
Compositional bias789-814Polar residues
Region789-882Disordered
Compositional bias815-838Basic and acidic residues
Compositional bias839-868Polar residues

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    882
  • Mass (Da)
    101,244
  • Last updated
    2002-03-01 v1
  • MD5 Checksum
    2ABCE09B53055E609E9B18FC3C334BCC
MNTADVPDNLQSWGQQPSSSYSNTQQHSQMTNLPPINHNNLCDTEPMNEDFQLQDVQADELQKQQKQQEQQHIQQQNAQRFIAQSRQPHSNILRFPQPPITSIKTNSHAFYPQQEVTQVRPKKHRVSMTNAEAALTPGMPPEKQAAKKRNIGQFSTDTVPAGIGMIGIPFESTSKPLQIQQFRNPQDAPVRKLTSDLIKTYKAINESFYLRKQVRRDRHKSQDAGKPKGSKDGSGASLTDTFSIHNAIPITSSDNHYQQDAHQNAPPLLDTNAPPTSTMVVPMRTETDLQQQQRQKSSRGGPYNNGYDDQNYDYILKNGEIFDKRYVILSDTPVGKGSFGQVTKAYDTLNKEEVAIKIIKNKKTFFDQAQIEIHLLELTNAHDKDNKYNIVTLKGHFVHRAHLCLVFELLSYNLYDLLKNTSFRGVSLNLARKFAQQLGKTLLFLSSPELSIIHCDLKPENVLLVNAKRSQIRVIDFGSSCQTGHRIYQYIQSRFYRSPEVLLGIAYDTKIDMWSLGCILVEMHTGEPLFAGSSEVDQMMKIVEVLGMPPKEMLDIGPKTHKYFDKTEDGIYYCKKTRDGYRHTYKAPGARKLHEILGVTSGGPGGRRLGEPGHSVEDYSKFKDLIKRMLQFDPKQRISPYYVVRHPFLKQKEERVPSQPPVSHSNLQQQQQLYIQQPSSQMSQVMESPSVGSVYVEDNGMYRQAPGSSANPISVTSSFDEGDAMEVDAGRRRFSAHQQNYHNPNYQYSQPQQQQQQQYQQTQRTQLEQQQKQAQLQQQLQQQQMQQQQQQQQQRQHMPQAQSSSQQHLQSRARPRQQDQNEWRNQFELDDTFQQKQRKVDDSVSNQISRNQFNPQQVSMTHGNVNANNREMEKLDYPNNKL

Features

Showing features for compositional bias.

TypeIDPosition(s)Description
Compositional bias212-227Basic and acidic residues
Compositional bias255-305Polar residues
Compositional bias789-814Polar residues
Compositional bias815-838Basic and acidic residues
Compositional bias839-868Polar residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AY064464
EMBL· GenBank· DDBJ
AAL40874.1
EMBL· GenBank· DDBJ
mRNA
Z69885
EMBL· GenBank· DDBJ
CAA93756.2
EMBL· GenBank· DDBJ
Genomic DNA

Genome annotation databases

Similar Proteins

Disclaimer

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