Q8WPM9 · Q8WPM9_OIKDI

Function

function

Unusual broad substrate spectrum amino acid:sodium cotransporter that promotes absorption of the D isomers of essential amino acids. Neutral amino acids are the preferred substrates, especially methionine and phenylalanine.

Features

Showing features for binding site.

167450100150200250300350400450500550600650
TypeIDPosition(s)Description
Binding site94Na+ 1 (UniProtKB | ChEBI)
Binding site96Na+ 1 (UniProtKB | ChEBI)
Binding site97Na+ 1 (UniProtKB | ChEBI)
Binding site101Na+ 1 (UniProtKB | ChEBI)
Binding site353Na+ 1 (UniProtKB | ChEBI)
Binding site385Na+ 1 (UniProtKB | ChEBI)
Binding site451Na+ 1 (UniProtKB | ChEBI)

GO annotations

all annotationsall molecular functionvirus receptor activitydna bindingrna bindingcytoskeletal motor activitycatalytic activitygtpase activitystructural molecule activitytransporter activitycytoskeletal protein bindinglipid bindingcyclase activityantioxidant activityoxidoreductase activitytransferase activityhydrolase activitylyase activityisomerase activityligase activityprotein tag activitycargo receptor activityhistone bindingprotein folding chaperonetranslation regulator activitynutrient reservoir activityreceptor ligand activitymolecular transducer activitymolecular adaptor activitytoxin activitycell adhesion mediator activitymolecular function regulator activityvirus coreceptor activitycatalytic activity, acting on a proteincatalytic activity, acting on dnacatalytic activity, acting on rnamolecular carrier activitytranscription regulator activitygeneral transcription initiation factor activitymolecular sensor activitymolecular sequestering activityatp-dependent activityother molecular functionall biological processmitotic cell cyclecytokinesiscytoplasmic translationimmune system processmuscle system processcirculatory system processrenal system processrespiratory system processcarbohydrate metabolic processgeneration of precursor metabolites and energydna replicationdna repairdna recombinationchromatin organizationdna-templated transcriptionregulation of dna-templated transcriptiontrna metabolic processprotein foldingprotein glycosylationamino acid metabolic processmodified amino acid metabolic processlipid metabolic processvitamin metabolic processsulfur compound metabolic processintracellular protein transportnucleocytoplasmic transportautophagyinflammatory responsemitochondrion organizationcytoskeleton organizationmicrotubule-based movementperoxisome organizationlysosome organizationchromosome segregationcell adhesionestablishment or maintenance of cell polarityprogrammed cell deathphotosynthesismrna metabolic processsnrna metabolic processvesicle-mediated transportreproductive processdigestive system processsignalingcell differentiationprotein catabolic processextracellular matrix organizationregulatory ncrna-mediated gene silencingtelomere organizationcell junction organizationwound healingribosome biogenesiscilium organizationanatomical structure developmentcell motilitynervous system processendocrine processprotein maturationtransmembrane transportnucleobase-containing small molecule metabolic processhepaticobiliary system processmembrane organizationprotein-containing complex assemblycell wall organization or biogenesisnitrogen cycle metabolic processprotein localization to plasma membranedefense response to other organismdetoxificationmeiotic nuclear divisionmitotic nuclear divisionmitochondrial gene expressioncarbohydrate derivative metabolic processother biological processall cellular componentnuclear chromosomeextracellular regionextracellular spacecell wallnucleusnuclear envelopenucleoplasmchromosomenucleolusmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuslipid dropletmicrotubule organizing centercytosolribosomecytoskeletonplasma membraneciliumplastidthylakoidexternal encapsulating structureextracellular matrixcytoplasmic vesicleorganelleother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentmembrane
Cellular Componentsynapse
Molecular Functionglycine:sodium symporter activity
Molecular Functionmetal ion binding
Biological Processglycine import across plasma membrane
Biological Processsynaptic transmission, glycinergic

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Transporter

Gene names

    • Name
      BAC001.6

Organism names

Accessions

  • Primary accession
    Q8WPM9

Subcellular Location

Membrane
; Multi-pass membrane protein

Features

Showing features for transmembrane.

TypeIDPosition(s)Description
Transmembrane88-106Helical
Transmembrane118-139Helical
Transmembrane160-183Helical
Transmembrane272-291Helical
Transmembrane298-318Helical
Transmembrane346-367Helical
Transmembrane379-402Helical
Transmembrane438-460Helical
Transmembrane481-508Helical
Transmembrane514-534Helical
Transmembrane555-574Helical
Transmembrane594-614Helical

Keywords

  • Cellular component

PTM/Processing

Features

Showing features for disulfide bond.

TypeIDPosition(s)Description
Disulfide bond203↔212

Keywords

Family & Domains

Sequence similarities

Keywords

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    674
  • Mass (Da)
    75,155
  • Last updated
    2002-03-01 v1
  • Checksum
    9D318B68D64416E6
MAKVKQQGLMNFQVKNELPNRMASAANDSFTEESSSEKVKLTRLREGFNFQTGNLSNSFIFISRDFSTDLSELRSLPGRQSWGNKIEFMLSMVGYAVGLGNIWRFPYLTYKNGGGAFLIPYLICLVLCGLPIFLFEVALGQFCSQGPIKAFNGVPIFKGIGYAMVAVSTIIGCYYNVIISYTLRYLFESFQAFSTGELPWANCDNSWNDEKCMDVGRLNRCRSIQANGTLEVPAMCQLNHTNREAPSQQYFENHILEMSDSIEDVGLPKADLVLYLAISYAILFICLAKGIQSTGKAVYITSTFPYVVLTTLLIVGLTKDGSLNGIKYFLTPEWERLKDMSVWKDAATQIFFSLSASWGGLITLASYNEFDNNIVRDTLIVVLTNSATSIFAGLTIFSYLGFMAHSMGVEVEDVARQGPGLAFIAYPEALTQISTGSIVWSVLFFTMLLMLGLSTMFATMNTIITCCSDAFPQLRKRQASFTAVLCVFLFLLGIPMTTRAGLYILTLFDDFGGSYALLVISVAEMVSICFIYGLDNFCSDIQIMIKRPVGMFWRICWKFVSPVLLTAVFIAVLANWKVSTLGNYVYPNWTNYPAVGLILFSVLFIPLMAIHHVIKKGSIKAACEPTSHWGPLNSENRLNTRYENRKHFTRDPHRFIDYTSSGQTLLSSGASFVS

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF374376
EMBL· GenBank· DDBJ
AAL56437.1
EMBL· GenBank· DDBJ
Genomic DNA

Similar Proteins

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