Q8W3D0 · PDX12_ORYSJ

Function

function

Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by PDX2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers.

Miscellaneous

Vitamin B6 is an essential quencher of singlet oxygen in plants, that can protect cellular membranes from lipid peroxidation.

Catalytic activity

Pathway

Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site42D-ribose 5-phosphate (UniProtKB | ChEBI)
Active site99Schiff-base intermediate with D-ribose 5-phosphate
Binding site171D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site183D-glyceraldehyde 3-phosphate (UniProtKB | ChEBI)
Binding site232D-ribose 5-phosphate (UniProtKB | ChEBI)
Binding site253-254D-ribose 5-phosphate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Molecular Functionamine-lyase activity
Molecular Functionpyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity
Biological Processamino acid metabolic process
Biological Processpyridoxal phosphate biosynthetic process
Biological Processpyridoxine biosynthetic process

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable pyridoxal 5'-phosphate synthase subunit PDX1.2
  • EC number
  • Short names
    PLP synthase subunit PDX1.2

Gene names

    • Name
      PDX12
    • ORF names
      OJ1136E01.11, OSJNBa0046L02.5
    • Ordered locus names
      Os10g0100700, LOC_Os10g01080

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Nipponbare
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > Liliopsida > Poales > Poaceae > BOP clade > Oryzoideae > Oryzeae > Oryzinae > Oryza > Oryza sativa

Accessions

  • Primary accession
    Q8W3D0
  • Secondary accessions
    • B7E4V8
    • Q7G6W0
    • Q7XHH7

Proteomes

Genome annotation databases

PTM/Processing

Features

Showing features for chain, modified residue (large scale data).

TypeIDPosition(s)SourceDescription
ChainPRO_00002706281-313UniProtProbable pyridoxal 5'-phosphate synthase subunit PDX1.2
Modified residue (large scale data)24PTMeXchangePhosphoserine

Proteomic databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Sequence similarities

Belongs to the PdxS/SNZ family.

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    313
  • Mass (Da)
    33,149
  • Last updated
    2002-03-01 v1
  • Checksum
    62A60E7A039FAAD9
MASDGTDVVALYGGANGLSHKSGSFSVKVGLAQMLRGGVIMDVVTPEQARIAEEAGACAVMALERVPADIRAQGGVARMSDPGLIRDIKRSVTIPVMAKARIGHLVEAQILEAIGVDYVDESEVLTLADDAHHINKNNFRVPFVCGCRDLGEALRRIREGAAMIRTKGEAGTGNVVEAVRHVRSVMGDIRALRSMDDDEVFSYAKRIAAPYDLVMQTKQLGRLPVVQFAAGGVATPADAALMMQLGCDGVFVGSGIFKSGDPALRARAIVQAVTHYSDPKILAEVSSGLGEAMVGINLSDPKIHVERFAARSD

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AC079632
EMBL· GenBank· DDBJ
AAL73561.1
EMBL· GenBank· DDBJ
Genomic DNA
AC108883
EMBL· GenBank· DDBJ
AAM08638.1
EMBL· GenBank· DDBJ
Genomic DNA
DP000086
EMBL· GenBank· DDBJ
AAP51743.1
EMBL· GenBank· DDBJ
Genomic DNA
AP008216
EMBL· GenBank· DDBJ
BAF25924.1
EMBL· GenBank· DDBJ
Genomic DNA
AP014966
EMBL· GenBank· DDBJ
BAT09558.1
EMBL· GenBank· DDBJ
Genomic DNA
AK060323
EMBL· GenBank· DDBJ
BAG87405.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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