Q8W1D5 · CIPKP_ARATH

Function

function

CIPK serine-threonine protein kinases interact with CBL proteins. Binding of a CBL protein to the regulatory NAF domain of CIPK protein lead to the activation of the kinase in a calcium-dependent manner (By similarity).

Catalytic activity

Cofactor

Mn2+ (UniProtKB | Rhea| CHEBI:29035 )

Features

Showing features for binding site, active site.

TypeIDPosition(s)Description
Binding site49-57ATP (UniProtKB | ChEBI)
Binding site72ATP (UniProtKB | ChEBI)
Active site165Proton acceptor

GO annotations

AspectTerm
Molecular FunctionATP binding
Molecular Functionprotein serine kinase activity
Molecular Functionprotein serine/threonine kinase activity
Biological Processdefense response to fungus
Biological Processintracellular potassium ion homeostasis
Biological Processresponse to hypoxia
Biological Processsignal transduction

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    CBL-interacting serine/threonine-protein kinase 25
  • EC number
  • Alternative names
    • SNF1-related kinase 3.25
    • SOS2-like protein kinase PKS25

Gene names

    • Name
      CIPK25
    • Synonyms
      PKS25, SnRK3.25
    • ORF names
      T11H3.120
    • Ordered locus names
      At5g25110

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8W1D5
  • Secondary accessions
    • Q94A54

Proteomes

Organism-specific databases

Genome annotation databases

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00003372251-488CBL-interacting serine/threonine-protein kinase 25
Modified residue187Phosphoserine
Modified residue201Phosphothreonine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, region.

TypeIDPosition(s)Description
Domain43-297Protein kinase
Region183-212Activation loop
Domain336-361NAF
Region365-395PPI

Domain

The activation loop within the kinase domain is the target of phosphorylation/activation by upstream protein kinases. The PPI motif mediates the interaction with the ABI (abscisic acid-insensitive) phosphatases (By similarity).

Sequence similarities

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    488
  • Mass (Da)
    55,563
  • Last updated
    2002-03-01 v1
  • Checksum
    2F406DE095498243
MGSKLKLYPLLNHSSVFHPDSRYQSAPTMEEEQQQLRVLFAKYEMGRLLGKGTFGKVYYGKEITTGESVAIKIINKDQVKREGMMEQIKREISIMRLVRHPNIVELKEVMATKTKIFFIMEYVKGGELFSKIVKGKLKEDSARKYFQQLISAVDFCHSRGVSHRDLKPENLLVDENGDLKVSDFGLSALPEQILQDGLLHTQCGTPAYVAPEVLRKKGYDGAKGDIWSCGIILYVLLAGFLPFQDENLMKMYRKIFKSEFEYPPWFSPESKRLISKLLVVDPNKRISIPAIMRTPWFRKNINSPIEFKIDELEIQNVEDETPTTTATTATTTTTPVSPKFFNAFEFISSMSSGFDLSSLFESKRKLRSMFTSRWSASEIMGKLEGIGKEMNMKVKRTKDFKVKLFGKTEGRKGQIAVTAEVFEVAPEVAVVELCKSAGDTLEYNRLYEEHVRPALEEIVWSWHGDNHNNNIVKSNGNYVSDENSGSDC

Features

Showing features for sequence conflict.

TypeIDPosition(s)Description
Sequence conflict334in Ref. 4; AAN72221/AAK91377

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AF448226
EMBL· GenBank· DDBJ
AAL41008.1
EMBL· GenBank· DDBJ
mRNA
AC005964
EMBL· GenBank· DDBJ
-Genomic DNA No translation available.
CP002688
EMBL· GenBank· DDBJ
AED93402.1
EMBL· GenBank· DDBJ
Genomic DNA
AY050360
EMBL· GenBank· DDBJ
AAK91377.1
EMBL· GenBank· DDBJ
mRNA
BT002209
EMBL· GenBank· DDBJ
AAN72221.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

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