Q8VZJ7 · P4H9_ARATH

Function

function

Catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in proline-rich peptide sequences of plant glycoproteins and other proteins. Hydroxyprolines are important constituent of many plant cell wall glycoproteins such as extensins, hydroxyproline-rich glycoproteins, lectins and arabinogalactan proteins.

Catalytic activity

Cofactor

Protein has several cofactor binding sites:
Fe2+ (UniProtKB | Rhea| CHEBI:29033 )

Note: Binds 1 Fe2+ ion per subunit.
L-ascorbate (UniProtKB | Rhea| CHEBI:38290 )

Features

Showing features for binding site.

TypeIDPosition(s)Description
Binding site182Fe cation (UniProtKB | ChEBI)
Binding site184Fe cation (UniProtKB | ChEBI)
Binding site264Fe cation (UniProtKB | ChEBI)
Binding site2742-oxoglutarate (UniProtKB | ChEBI)

GO annotations

AspectTerm
Cellular Componentendoplasmic reticulum membrane
Cellular ComponentGolgi apparatus
Cellular ComponentGolgi medial cisterna
Molecular Functioniron ion binding
Molecular FunctionL-ascorbic acid binding
Molecular Functionprocollagen-proline 4-dioxygenase activity

Keywords

Enzyme and pathway databases

Names & Taxonomy

Protein names

  • Recommended name
    Probable prolyl 4-hydroxylase 9
  • EC number
  • Short names
    AtP4H9

Gene names

    • Name
      P4H9
    • ORF names
      F17I5.100
    • Ordered locus names
      At4g33910

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8VZJ7
  • Secondary accessions
    • O81759

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Features

Showing features for topological domain, transmembrane.

TypeIDPosition(s)Description
Topological domain1-12Cytoplasmic
Transmembrane13-33Helical; Signal-anchor for type II membrane protein
Topological domain34-288Lumenal

Keywords

PTM/Processing

Features

Showing features for chain, glycosylation.

TypeIDPosition(s)Description
ChainPRO_00004293421-288Probable prolyl 4-hydroxylase 9
Glycosylation221N-linked (GlcNAc...) asparagine
Glycosylation255N-linked (GlcNAc...) asparagine

Keywords

Proteomic databases

PTM databases

Expression

Gene expression databases

Interaction

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain.

TypeIDPosition(s)Description
Domain164-283Fe2OG dioxygenase

Sequence similarities

Belongs to the P4HA family.

Keywords

Phylogenomic databases

Family and domain databases

Sequence

  • Sequence status
    Complete
  • Length
    288
  • Mass (Da)
    32,279
  • Last updated
    2002-03-01 v1
  • Checksum
    1A8BEF7A3135A534
MKSRLKSYRRKKLGLATVIVFCSLCFLFGFYGSTLLSQNVPRVKPRLRMLDMVENGEEEASSMPHGVTGEESIGSIPFQVLSWRPRAIYFPNFATAEQCQAIIERAKVNLKPSALALRKGETAENTKGTRTSSGTFISASEESTGALDFVERKIARATMIPRSHGESFNILRYELGQKYDSHYDVFNPTEYGPQSSQRIASFLLYLSDVEEGGETMFPFENGSNMGIGYDYKQCIGLKVKPRKGDGLLFYSVFPNGTIDQTSLHGSCPVTKGEKWVATKWIRDQDQEE

Sequence caution

The sequence CAA19873.1 differs from that shown. Reason: Erroneous gene model prediction
The sequence CAB80108.1 differs from that shown. Reason: Erroneous gene model prediction

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AL031032
EMBL· GenBank· DDBJ
CAA19873.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
AL161584
EMBL· GenBank· DDBJ
CAB80108.1
EMBL· GenBank· DDBJ
Genomic DNA Sequence problems.
CP002687
EMBL· GenBank· DDBJ
AEE86292.1
EMBL· GenBank· DDBJ
Genomic DNA
AY064069
EMBL· GenBank· DDBJ
AAL36425.1
EMBL· GenBank· DDBJ
mRNA
AY096377
EMBL· GenBank· DDBJ
AAM20018.1
EMBL· GenBank· DDBJ
mRNA
AY086254
EMBL· GenBank· DDBJ
AAM64328.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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