Q8VZ80 · PLT5_ARATH
- ProteinPolyol transporter 5
- GenePLT5
- StatusUniProtKB reviewed (Swiss-Prot)
- Amino acids539 (go to sequence)
- Protein existenceEvidence at protein level
- Annotation score5/5
Function
function
Plasma membrane broad-spectrum sugar-proton symporter. Mediates the uptake of linear polyols such as sorbitol, xylitol, erythritol or glycerol. Can transport the cyclic polyol myo-inositol and different hexoses, pentoses (including ribose), tetroses and sugar alcohols.
Kinetics
KM | SUBSTRATE | pH | TEMPERATURE[C] | NOTES | EVIDENCE | |
---|---|---|---|---|---|---|
0.5 mM | sorbitol | |||||
1.5 mM | glucose | |||||
3.5 mM | myo-inositol | |||||
23.4 mM | glycerol |
Determined at -60 mV (membrane potential) and an extracellular pH of 5.5.
pH Dependence
Optimum extracellular pH is 4.5 for sorbitol as substrate.
GO annotations
all annotations | all molecular function | nucleotide binding | molecular_function | nucleic acid binding | dna binding | chromatin binding | dna-binding transcription factor activity | rna binding | cytoskeletal motor activity | catalytic activity | nuclease activity | signaling receptor binding | structural molecule activity | transporter activity | binding | protein binding | translation factor activity, rna binding | lipid binding | kinase activity | transferase activity | hydrolase activity | oxygen binding | enzyme regulator activity | carbohydrate binding | signaling receptor activity | translation regulator activity | transcription regulator activity | other molecular function | all biological process | carbohydrate metabolic process | generation of precursor metabolites and energy | nucleobase-containing compound metabolic process | dna metabolic process | translation | lipid metabolic process | transport | response to stress | cell cycle | cell communication | signal transduction | cell-cell signaling | multicellular organism development | circadian rhythm | biological_process | metabolic process | catabolic process | biosynthetic process | response to light stimulus | response to external stimulus | tropism | response to biotic stimulus | response to abiotic stimulus | response to endogenous stimulus | embryo development | post-embryonic development | fruit ripening | abscission | pollination | flower development | cellular process | programmed cell death | photosynthesis | cellular component organization | cell growth | protein metabolic process | cellular homeostasis | secondary metabolic process | reproductive process | cell differentiation | protein modification process | growth | epigenetic regulation of gene expression | response to chemical | anatomical structure development | regulation of molecular function | other biological process | all cellular component | cellular_component | extracellular region | cell wall | intracellular anatomical structure | nucleus | nuclear envelope | nucleoplasm | nucleolus | cytoplasm | mitochondrion | lysosome | endosome | vacuole | peroxisome | endoplasmic reticulum | golgi apparatus | cytosol | ribosome | cytoskeleton | plasma membrane | chloroplast | plastid | thylakoid | membrane | external encapsulating structure | other cellular component | |||
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Aspect | Term | |
---|---|---|
Cellular Component | plasma membrane | |
Molecular Function | carbohydrate:proton symporter activity | |
Molecular Function | D-ribose transmembrane transporter activity | |
Molecular Function | D-xylose transmembrane transporter activity | |
Molecular Function | galactose transmembrane transporter activity | |
Molecular Function | glucose transmembrane transporter activity | |
Molecular Function | glycerol transmembrane transporter activity | |
Molecular Function | mannitol transmembrane transporter activity | |
Molecular Function | monosaccharide transmembrane transporter activity | |
Molecular Function | myo-inositol transmembrane transporter activity | |
Molecular Function | sorbitol transmembrane transporter activity | |
Biological Process | lateral root formation |
Keywords
- Biological process
Protein family/group databases
Names & Taxonomy
Protein names
- Recommended namePolyol transporter 5
- Alternative names
Gene names
Organism names
- Strain
- Taxonomic lineageEukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis
Accessions
- Primary accessionQ8VZ80
- Secondary accessions
Proteomes
Organism-specific databases
Genome annotation databases
Subcellular Location
UniProt Annotation
GO Annotation
Cell membrane ; Multi-pass membrane protein
Features
Showing features for transmembrane.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Transmembrane | 37-57 | Helical; Name=1 | ||||
Sequence: FACAILASMTSILLGYDIGVM | ||||||
Transmembrane | 73-93 | Helical; Name=2 | ||||
Sequence: LQIGILAGSLNIYSLIGSCAA | ||||||
Transmembrane | 104-124 | Helical; Name=3 | ||||
Sequence: YTIVLAGAIFFAGAILMGLSP | ||||||
Transmembrane | 127-147 | Helical; Name=4 | ||||
Sequence: AFLMFGRFIAGIGVGYALMIA | ||||||
Transmembrane | 165-185 | Helical; Name=5 | ||||
Sequence: SFPEVFINAGIMLGYVSNLAF | ||||||
Transmembrane | 196-216 | Helical; Name=6 | ||||
Sequence: LMLGIGAVPSVILAIGVLAMP | ||||||
Transmembrane | 296-316 | Helical; Name=7 | ||||
Sequence: IAAIGIHFFQQASGIDAVVLF | ||||||
Transmembrane | 333-353 | Helical; Name=8 | ||||
Sequence: LLATVAVGVVKTSFILVATFL | ||||||
Transmembrane | 364-384 | Helical; Name=9 | ||||
Sequence: LTSVGGMVLSLAALGTSLTII | ||||||
Transmembrane | 391-411 | Helical; Name=10 | ||||
Sequence: VMWAVVVAIATVMTYVATFSI | ||||||
Transmembrane | 433-453 | Helical; Name=11 | ||||
Sequence: GSSMGVVVNRVTSGVISISFL | ||||||
Transmembrane | 463-483 | Helical; Name=12 | ||||
Sequence: GAFYLFGGIATVAWVFFYTFL |
Keywords
- Cellular component
PTM/Processing
Features
Showing features for chain.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Chain | PRO_0000259873 | 1-539 | Polyol transporter 5 | |||
Sequence: MTGATPENRTAPSPPPVKHVPESVLPAKPPKRNNYAFACAILASMTSILLGYDIGVMSGAMIYIKRDLKINDLQIGILAGSLNIYSLIGSCAAGRTSDWIGRRYTIVLAGAIFFAGAILMGLSPNYAFLMFGRFIAGIGVGYALMIAPVYTAEVSPASSRGFLNSFPEVFINAGIMLGYVSNLAFSNLPLKVGWRLMLGIGAVPSVILAIGVLAMPESPRWLVMQGRLGDAKRVLDKTSDSPTEATLRLEDIKHAAGIPADCHDDVVQVSRRNSHGEGVWRELLIRPTPAVRRVMIAAIGIHFFQQASGIDAVVLFSPRIFKTAGLKTDHQQLLATVAVGVVKTSFILVATFLLDRIGRRPLLLTSVGGMVLSLAALGTSLTIIDQSEKKVMWAVVVAIATVMTYVATFSIGAGPITWVYSSEIFPLRLRSQGSSMGVVVNRVTSGVISISFLPMSKAMTTGGAFYLFGGIATVAWVFFYTFLPETQGRMLEDMDELFSGFRWRDSKSKPKGNPEKTVPNPEVEIGSNKQWKEGDTQSS |
Proteomic databases
PTM databases
Expression
Tissue specificity
Highly expressed in roots. Expressed in vascular tissue of leaves, sepals and siliques.
Induction
By wounding and insect feeding.
Gene expression databases
Structure
Family & Domains
Features
Showing features for region, compositional bias.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Region | 1-24 | Disordered | ||||
Sequence: MTGATPENRTAPSPPPVKHVPESV | ||||||
Compositional bias | 9-23 | Pro residues | ||||
Sequence: RTAPSPPPVKHVPES | ||||||
Region | 503-539 | Disordered | ||||
Sequence: WRDSKSKPKGNPEKTVPNPEVEIGSNKQWKEGDTQSS |
Sequence similarities
Keywords
- Domain
Phylogenomic databases
Family and domain databases
Sequence
- Sequence statusComplete
- Length539
- Mass (Da)58,103
- Last updated2006-11-28 v2
- Checksum36B389284E5563A0
Sequence caution
Features
Showing features for compositional bias, sequence conflict.
Type | ID | Position(s) | Description | |||
---|---|---|---|---|---|---|
Compositional bias | 9-23 | Pro residues | ||||
Sequence: RTAPSPPPVKHVPES | ||||||
Sequence conflict | 527 | in Ref. 3; AAL38359/AAM10180 | ||||
Sequence: S → L |
Keywords
- Technical term
Sequence databases
Nucleotide Sequence | Protein Sequence | Molecule Type | Status | |
---|---|---|---|---|
AB026654 EMBL· GenBank· DDBJ | BAB01812.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
CP002686 EMBL· GenBank· DDBJ | AEE76153.1 EMBL· GenBank· DDBJ | Genomic DNA | ||
AY065183 EMBL· GenBank· DDBJ | AAL38359.1 EMBL· GenBank· DDBJ | mRNA | Frameshift | |
AY081618 EMBL· GenBank· DDBJ | AAM10180.1 EMBL· GenBank· DDBJ | mRNA |