Q8VYA5 · RSZ33_ARATH

Function

function

Splicing factor involved in constitutive and/or alternative splicing. Regulates the splicing of its own pre-mRNA and the alternative splicing of RS30, RS31 and RS34. Associates the cyclin-dependent kinase G1 (CDKG1) with the spliceosome and recruits it to U1 snRNP to facilitate splicing.

Miscellaneous

The splicing pattern of the pre-mRNA is regulated in a tissue-specific manner and by development, and changes in response to various types of abiotic stresses (PubMed:17319848), but is not affected by the light/dark regimes (PubMed:24763593).

GO annotations

all annotationsall molecular functionnucleotide bindingmolecular_functionnucleic acid bindingdna bindingchromatin bindingdna-binding transcription factor activityrna bindingcytoskeletal motor activitycatalytic activitynuclease activitysignaling receptor bindingstructural molecule activitytransporter activitybindingprotein bindingtranslation factor activity, rna bindinglipid bindingkinase activitytransferase activityhydrolase activityoxygen bindingenzyme regulator activitycarbohydrate bindingsignaling receptor activitytranslation regulator activitytranscription regulator activityother molecular functionall biological processcarbohydrate metabolic processgeneration of precursor metabolites and energynucleobase-containing compound metabolic processdna metabolic processtranslationlipid metabolic processtransportresponse to stresscell cyclecell communicationsignal transductioncell-cell signalingmulticellular organism developmentcircadian rhythmbiological_processmetabolic processcatabolic processbiosynthetic processresponse to light stimulusresponse to external stimulustropismresponse to biotic stimulusresponse to abiotic stimulusresponse to endogenous stimulusembryo developmentpost-embryonic developmentfruit ripeningabscissionpollinationflower developmentcellular processprogrammed cell deathphotosynthesiscellular component organizationcell growthprotein metabolic processcellular homeostasissecondary metabolic processreproductive processcell differentiationprotein modification processgrowthepigenetic regulation of gene expressionresponse to chemicalanatomical structure developmentregulation of molecular functionother biological processall cellular componentcellular_componentextracellular regioncell wallintracellular anatomical structurenucleusnuclear envelopenucleoplasmnucleoluscytoplasmmitochondrionlysosomeendosomevacuoleperoxisomeendoplasmic reticulumgolgi apparatuscytosolribosomecytoskeletonplasma membranechloroplastplastidthylakoidmembraneexternal encapsulating structureother cellular component
Cell color indicative of number of GO terms
AspectTerm
Cellular Componentnuclear speck
Cellular Componentspliceosomal complex
Molecular FunctionmRNA binding
Molecular Functionzinc ion binding
Biological ProcessmRNA splicing, via spliceosome
Biological ProcessRNA splicing
Biological Processspliceosomal complex assembly

Keywords

Names & Taxonomy

Protein names

  • Recommended name
    Serine/arginine-rich splicing factor RS2Z33
  • Alternative names
    • RS-containing zinc finger protein 33 (At-RS2Z33; At-RSZ33; AtRSZ33)

Gene names

    • Name
      RS2Z33
    • Synonyms
      RSZ33
    • ORF names
      F3G5.13
    • Ordered locus names
      At2g37340

Organism names

  • Taxonomic identifier
  • Strain
    • cv. Columbia
  • Taxonomic lineage
    Eukaryota > Viridiplantae > Streptophyta > Embryophyta > Tracheophyta > Spermatophyta > Magnoliopsida > eudicotyledons > Gunneridae > Pentapetalae > rosids > malvids > Brassicales > Brassicaceae > Camelineae > Arabidopsis

Accessions

  • Primary accession
    Q8VYA5
  • Secondary accessions
    • F4IQ37
    • Q67Y02
    • Q9FYA7
    • Q9ZUT2

Proteomes

Organism-specific databases

Genome annotation databases

Subcellular Location

Keywords

PTM/Processing

Features

Showing features for chain, modified residue.

TypeIDPosition(s)Description
ChainPRO_00004169981-290Serine/arginine-rich splicing factor RS2Z33
Modified residue164Phosphoserine
Modified residue166Phosphoserine
Modified residue180Phosphoserine
Modified residue202Phosphoserine
Modified residue204Phosphoserine
Modified residue211Phosphoserine
Modified residue219Phosphoserine
Modified residue226Phosphoserine
Modified residue230Phosphoserine
Modified residue239Phosphoserine
Modified residue245Phosphoserine
Modified residue256Phosphoserine
Modified residue271Phosphoserine
Modified residue283Phosphoserine
Modified residue287Phosphoserine

Post-translational modification

Extensively phosphorylated on serine residues in the RS domain.

Keywords

Proteomic databases

PTM databases

Expression

Tissue specificity

Expressed in roots, flowers, anthers, pollen, ovules, style and developing seeds. Not detected in stems or leaves.

Gene expression databases

Interaction

Subunit

Component of the spliceosome. Interacts with SNRNP35, CDKG1, cyp59, SR33, SR34, RSZ21, RSZ22, SCL28, SCL30, SCL30A, SCL33 and SC35 (PubMed:10593939, PubMed:12176998, PubMed:15987817, PubMed:16497658, PubMed:23404887).
Interacts with MOS14 (PubMed:21738492).

Protein-protein interaction databases

Structure

Family & Domains

Features

Showing features for domain, zinc finger, region, compositional bias.

TypeIDPosition(s)Description
Domain11-81RRM
Zinc finger99-116CCHC-type 1
Zinc finger121-138CCHC-type 2
Region135-290Disordered
Compositional bias179-217Basic and acidic residues
Compositional bias267-282Basic and acidic residues

Sequence similarities

Keywords

Phylogenomic databases

Family and domain databases

Sequence & Isoforms

Align isoforms (3)
  • Sequence status
    Complete

This entry describes 3 isoforms produced by Alternative splicing.

Q8VYA5-1

This isoform has been chosen as the canonical sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

  • Length
    290
  • Mass (Da)
    32,893
  • Last updated
    2002-03-01 v1
  • Checksum
    4B0407A7E106EFA2
MPRYDDRYGNTRLYVGRLSSRTRTRDLERLFSRYGRVRDVDMKRDYAFVEFGDPRDADDARHYLDGRDFDGSRITVEFSRGAPRGSRDFDSRGPPPGAGRCFNCGVDGHWARDCTAGDWKNKCYRCGERGHIERNCKNSPKKLRRSGSYSRSPVRSRSPRRRRSPSRSLSRSRSYSRSRSPVRRRERSVEERSRSPKRMDDSLSPRARDRSPVLDDEGSPKIIDGSPPPSPKLQKEVGSDRDGGSPQDNGRNSVVSPVVGAGGDSSKEDRSPVDDDYEPNRTSPRGSESP

Q8VYA5-2

  • Name
    2
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical
    • 1-49: MPRYDDRYGNTRLYVGRLSSRTRTRDLERLFSRYGRVRDVDMKRDYAFV → MWENTPCMWSLLSSHFRNQ

Q8VYA5-3

  • Name
    3
  • See also
    sequence in UniParc or sequence clusters in UniRef
  • Differences from canonical

Sequence caution

The sequence BX842467 differs from that shown. Reason: Erroneous termination Truncated C-terminus.

Features

Showing features for alternative sequence, sequence conflict, compositional bias.

TypeIDPosition(s)Description
Alternative sequenceVSP_0431131-41in isoform 3
Alternative sequenceVSP_0431121-49in isoform 2
Sequence conflict50in Ref. 6; BAD44429
Sequence conflict139in Ref. 1; CAC03605
Sequence conflict173in Ref. 1; CAC03605
Compositional bias179-217Basic and acidic residues
Compositional bias267-282Basic and acidic residues

Keywords

Sequence databases

Nucleotide SequenceProtein SequenceMolecule TypeStatus
AJ293801
EMBL· GenBank· DDBJ
CAC03605.1
EMBL· GenBank· DDBJ
mRNA
AC005896
EMBL· GenBank· DDBJ
AAC98054.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC09385.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC09386.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
AEC09387.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
ANM63217.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
ANM63218.1
EMBL· GenBank· DDBJ
Genomic DNA
CP002685
EMBL· GenBank· DDBJ
ANM63219.1
EMBL· GenBank· DDBJ
Genomic DNA
AY072315
EMBL· GenBank· DDBJ
AAL61922.1
EMBL· GenBank· DDBJ
mRNA
AY114563
EMBL· GenBank· DDBJ
AAM47882.1
EMBL· GenBank· DDBJ
mRNA
AK176551
EMBL· GenBank· DDBJ
BAD44314.1
EMBL· GenBank· DDBJ
mRNA
BX842463
EMBL· GenBank· DDBJ
-mRNA No translation available.
BX842467
EMBL· GenBank· DDBJ
-mRNA No translation available.
AK176666
EMBL· GenBank· DDBJ
BAD44429.1
EMBL· GenBank· DDBJ
mRNA

Genome annotation databases

Similar Proteins

Disclaimer

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